Author

David G. Gorenstein

University of Texas USC Houston (retired) - Cited by 14,749 - Proteomics - aptamers - nanomedicine - structural biology - protein structure

Biography

David Gorenstein, Ph.D., joined UTHealth January 1, 2009 as Professor and Deputy Director of the IMM. Dr. Gorenstein. He was most recently the Associate Dean for Research, School of Medicine, the University of Texas Medical Branch at Galveston (UTMB) and the Charles Marc Pomerat Distinguished Professor in the Departments of Biochemistry & Molecular Biology and Neurosciences & Cell Biology. He has nearly 40 years experience in structural biology, drug design, nucleic acid and protein chemistry with over 240 publications. He currently has major translational research programs in proteomics and nanomedicine for both diagnostics and therapeutics, particularly in cancer.
Title
Cited by
Year
Phosphorous-31 NMR: Principles and applications
DG GorensteinAcademic Press, 2012201
598
2012
Encyclopedia of spectroscopy and spectrometry
RA Spragg, IR SpectrometersEncycl Spectrosc Spectrom, 2017334201
334
2017
Aptamers and the next generation of diagnostic reagents
V Thiviyanathan, DG GorensteinPROTEOMICS–Clinical Applications 6 (11-12), 563-573, 2012201
179
2012
RNA nanoparticles harboring annexin A2 aptamer can target ovarian cancer for tumor-specific doxorubicin delivery
F Pi, H Zhang, H Li, V Thiviyanathan, DG Gorenstein, AK Sood, P GuoNanomedicine: Nanotechnology, Biology and Medicine 13 (3), 1183-1193, 2017201
75
2017
Direct observation of the ion-pair dynamics at a protein–DNA interface by NMR spectroscopy
KM Anderson, A Esadze, M Manoharan, R Brüschweiler, DG Gorenstein, ...Journal of the American Chemical Society 135 (9), 3613-3619, 2013201
64
2013
Bone marrow endothelium-targeted therapeutics for metastatic breast cancer
J Mai, Y Huang, C Mu, G Zhang, R Xu, X Guo, X Xia, DE Volk, GL Lokesh, ...Journal of Controlled Release 187, 22-29, 2014201
63
2014
Blocking the adhesion cascade at the premetastatic niche for prevention of breast cancer metastasis
SA Kang, N Hasan, AP Mann, W Zheng, L Zhao, L Morris, W Zhu, ...Molecular Therapy 23 (6), 1044-1054, 2015201
59
2015
Therapeutic targeting of AXL receptor tyrosine kinase inhibits tumor growth and intraperitoneal metastasis in ovarian cancer models
P Kanlikilicer, B Ozpolat, B Aslan, R Bayraktar, N Gurbuz, ...Molecular Therapy-Nucleic Acids 9, 251-262, 2017201
57
2017
Entropic enhancement of protein-DNA affinity by oxygen-to-sulfur substitution in DNA phosphate
L Zandarashvili, D Nguyen, KM Anderson, MA White, DG Gorenstein, ...Biophysical journal 109 (5), 1026-1037, 2015201
54
2015
In vivo targeting of leukemia stem cells by directing parthenolide-loaded nanoparticles to the bone marrow niche
H Zong, S Sen, G Zhang, C Mu, ZF Albayati, DG Gorenstein, X Liu, ...Leukemia 30 (7), 1582-1586, 2016201
51
2016
The effect of soluble E-selectin on tumor progression and metastasis
S Kang, CA Blache, S Bajana, N Hasan, M Kamal, Y Morita, V Gupta, ...BMC cancer 16 (1), 1-13, 2016201
49
2016
A novel DNA aptamer for dual targeting of polymorphonuclear myeloid-derived suppressor cells and tumor cells
H Liu, J Mai, J Shen, J Wolfram, Z Li, G Zhang, R Xu, Y Li, C Mu, Y Zu, X Li, ...Theranostics 8 (1), 31, 2018201
43
2018
X-aptamer selection and validation
GL Lokesh, H Wang, CH Lam, V Thiviyanathan, N Ward, DG Gorenstein, ...RNA Nanostructures: Methods and Protocols, 151-174, 2017201
40
2017
Uterus-targeted liposomes for preterm labor management: studies in pregnant mice
JS Refuerzo, F Leonard, N Bulayeva, D Gorenstein, G Chiossi, ...Scientific reports 6 (1), 34710, 2016201
36
2016
Aggregation behavior of ibuprofen, cholic acid and dodecylphosphocholine micelles
P Prakash, A Sayyed-Ahmad, Y Zhou, DE Volk, DG Gorenstein, E Dial, ...Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (12), 3040-3047, 2012201
34
2012
Morph-X-Select: Morphology-based tissue aptamer selection for ovarian cancer biomarker discovery
H Wang, X Li, DE Volk, GLR Lokesh, MA Elizondo-Riojas, L Li, AM Nick, ...Biotechniques 61 (5), 249-259, 2016201
27
2016
E-selectin targeting PEGylated-thioaptamer prevents breast cancer metastases
Y Morita, M Kamal, SA Kang, R Zhang, GLR Lokesh, V Thiviyanathan, ...Molecular Therapy-Nucleic Acids 5, 2016201
27
2016
Thioaptamers targeting dengue virus type-2 envelope protein domain III
SHA Gandham, DE Volk, GLR Lokesh, M Neerathilingam, DG GorensteinBiochemical and biophysical research communications 453 (3), 309-315, 2014201
22
2014
X-aptamer technology identifies C4A and ApoB in blood as potential markers for schizophrenia
C Walss-Bass, GLR Lokesh, E Dyukova, DG Gorenstein, DL Roberts, ...Complex Psychiatry 5 (1), 52-59, 2019201
21
2019
Safety evaluation of intravenously administered mono-thioated aptamer against E-selectin in mice
SA Kang, B Tsolmon, AP Mann, W Zheng, L Zhao, YD Zhao, DE Volk, ...Toxicology and applied pharmacology 287 (1), 86-92, 2015201
17
2015