Author

Paul-Clark MJ

Senior Lecturer, Nottingham Trent University - Cited by 4,957 - Inflammation - Oxidative Stress - Iron/Heam Metabolism - Infection

Biography

I am a Reader in the School of Physics and Astronomy. On this site you will details of the courses I teach, and information about my research (papers, talks, movies, etc). The focus of my research is to understand how stars form, and what physical conditions are responsible for setting their properties. In the tabs above, you will find an overview of my work to date, as well as news of recent and upcoming papers.
Title
Cited by
Year
Critical role of toll-like receptors and nucleotide oligomerisation domain in the regulation of health and disease
JA Mitchell, MJ Paul-Clark, GW Clarke, SK McMaster, N CartwrightJournal of Endocrinology 193 (3), 323-330, 2007200
181
2007
Antiplatelet actions of statins and fibrates are mediated by PPARs
FY Ali, PCJ Armstrong, ARA Dhanji, AT Tucker, MJ Paul-Clark, JA Mitchell, ...Arteriosclerosis, thrombosis, and vascular biology 29 (5), 706-711, 2009200
138
2009
Aspirin and the in vitro linear relationship between thromboxane A2-mediated platelet aggregation and platelet production of thromboxane A2
PCJ Armstrong, NJ Truss, FY Ali, AA Dhanji, I Vojnovic, ZNM Zain, ...Journal of Thrombosis and Haemostasis 6 (11), 1933-1943, 2008200
75
2008
Selective NOD1 Agonists Cause Shock and Organ Injury/Dysfunction In Vivo
N Cartwright, O Murch, SK McMaster, MJ Paul-Clark, DA van Heel, ...American journal of respiratory and critical care medicine 175 (6), 595-603, 2007200
73
2007
Toll-like receptor 2 is essential for the sensing of oxidants during inflammation
MJ Paul-Clark, SK McMaster, R Sorrentino, S Sriskandan, LK Bailey, ...American journal of respiratory and critical care medicine 179 (4), 299-306, 2009200
73
2009
Innate immunity in human embryonic stem cells: comparison with adult human endothelial cells
G Földes, A Liu, R Badiger, M Paul-Clark, L Moreno, Z Lendvai, JS Wright, ...PloS one 5 (5), e10501, 2010201
69
2010
Differential effects of Gram‐positive versus Gram‐negative bacteria on NOSII and TNFα in macrophages: role of TLRs in synergy between the two
MJ Paul‐Clark, SK Mc Master, E Belcher, R Sorrentino, J Anandarajah, ...British journal of pharmacology 148 (8), 1067-1075, 2006200
62
2006
Intestinal injury and endotoxemia in children undergoing surgery for congenital heart disease
N Pathan, M Burmester, T Adamovic, M Berk, KW Ng, H Betts, D Macrae, ...American journal of respiratory and critical care medicine 184 (11), 1261-1269, 2011201
62
2011
Cigarette smoke inhibits macrophage sensing of Gram‐negative bacteria and lipopolysaccharide: relative roles of nicotine and oxidant stress
SK McMaster, MJ Paul‐Clark, M Walters, M Fleet, J Anandarajah, ...British journal of pharmacology 153 (3), 536-543, 2008200
59
2008
Role of pattern-recognition receptors in cardiovascular health and disease
JA Mitchell, B Ryffel, VFJ Quesniaux, N Cartwright, M Paul-ClarkBiochemical Society Transactions 35 (6), 1449-1452, 2007200
54
2007
Inflammatory transcriptome profiling of human monocytes exposed acutely to cigarette smoke
WR Wright, K Parzych, D Crawford, C Mein, JA Mitchell, MJ Paul-ClarkPLoS One 7 (2), e30120, 2012201
54
2012
Differential role of pannexin-1/ATP/P2X7 axis in IL-1β release by human monocytes
K Parzych, AV Zetterqvist, WR Wright, NS Kirkby, JA Mitchell, ...The FASEB Journal 31 (6), 2439, 2017201
49
2017
Pharmacology and therapeutic potential of pattern recognition receptors
MJ Paul-Clark, PM George, T Gatheral, K Parzych, WR Wright, ...Pharmacology & therapeutics 135 (2), 200-215, 2012201
46
2012
Calcitonin and prednisolone display antagonistic actions on bone and have synergistic effects in experimental arthritis
L Mancini, MJ Paul-Clark, G Rosignoli, R Hannon, JE Martin, I Macintyre, ...The American journal of pathology 170 (3), 1018-1027, 2007200
42
2007
Viral Toll Like Receptor activation of pulmonary vascular smooth muscle cells results in endothelin-1 generation; relevance to pathogenesis of pulmonary arterial hypertension
PM George, R Badiger, D Shao, MR Edwards, SJ Wort, MJ Paul-Clark, ...Biochemical and biophysical research communications 426 (4), 486-491, 2012201
36
2012
The peroxisome proliferator–activated receptor β/δ agonist GW0742 has direct protective effects on right heart hypertrophy
B Kojonazarov, H Luitel, A Sydykov, BK Dahal, MJ Paul-Clark, S Bonvini, ...Pulmonary circulation 3 (4), 926-9, 2013201
35
2013
Pattern recognition receptors and interleukin‐8 mediate effects of Gram‐positive and Gram‐negative bacteria on lung epithelial cell function
R Sorrentino, PM De Souza, S Sriskandan, C Duffin, MJ Paul‐Clark, ...British journal of pharmacology 154 (4), 864-871, 2008200
29
2008
Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll‐like receptor 4 responses in macrophages
L Moreno, SK McMaster, T Gatheral, LK Bailey, LS Harrington, ...British journal of pharmacology 160 (8), 1997-2007, 2010201
27
2010