Author

Hirokazu Sugiyama

The University of Tokyo - Cited by 1,474 - Chemical engineering - Process systems engineering - Pharmaceutical manufacturing

Biography

Dr. Hirokazu Sugiyama is a is board-certified Professor by the Aichi Medical University, Nagakute, Japan, renowned researcher and author in the specialty of Department of Nephrology and Rheumatology.
Title
Cited by
Year
Integrated design of biopharmaceutical manufacturing processes: Operation modes and process configurations for monoclonal antibody production
S Badr, K Okamura, N Takahashi, V Ubbenjans, H Shirahata, H SugiyamaComputers & Chemical Engineering 153, 107422, 2021202
18
2021
Superstructure-based process synthesis and economic assessment under uncertainty for solid drug product manufacturing
K Matsunami, F Sternal, K Yaginuma, S Tanabe, H Nakagawa, ...BMC Chemical Engineering 2, 1-16, 2020202
14
2020
Model-based assessment of temperature profiles in slow freezing for human induced pluripotent stem cells
Y Hayashi, I Horiguchi, M Kino-oka, H SugiyamaComputers & Chemical Engineering 144, 107150, 2021202
13
2021
Analysis of the effects of process parameters on start-up operation in continuous wet granulation
K Matsunami, A Ryckaert, M Peeters, S Badr, H Sugiyama, I Nopens, ...Processes 9 (9), 1502, 2021202
11
2021
Control strategy and methods for continuous direct compression processes
Y Suzuki, H Sugiyama, M Kano, R Shimono, G Shimada, R Furukawa, ...Asian Journal of Pharmaceutical Sciences 16 (2), 253-262, 2021202
9
2021
Data-driven anomaly detection and diagnostics for changeover processes in biopharmaceutical drug product manufacturing
A Zeberli, S Badr, C Siegmund, M Mattern, H SugiyamaChemical Engineering Research and Design 167, 53-62, 2021202
8
2021
Cost–benefit analysis of monoclonal antibody cultivation scenarios in terms of life cycle environmental impact and operating cost
E Amasawa, H Kuroda, K Okamura, S Badr, H SugiyamaACS Sustainable Chemistry & Engineering 9 (42), 14012-14021, 2021202
8
2021
Digital models in biotechnology: Towards multi-scale integration and implementation
FSF Hartmann, IA Udugama, GM Seibold, H Sugiyama, KV GernaeyBiotechnology Advances, 108015, 2022202
7
2022
7
2022
A dynamic and probabilistic design space determination method for mesenchymal stem cell cultivation processes
K Hirono, I A. Udugama, Y Hayashi, M Kino-oka, H SugiyamaIndustrial & Engineering Chemistry Research 61 (20), 7009-7019, 2022202
5
2022
Approach to establishment of control strategy for oral solid dosage forms using continuous manufacturing
H Ishimoto, M Kano, H Sugiyama, H Takeuchi, K Terada, A Aoyama, ...Chemical and Pharmaceutical Bulletin 69 (2), 211-217, 2021202
5
2021
Challenges and opportunities for process systems engineering in a changed world
R Gani, X Chen, MR Eden, SS Mansouri, M Martin, IM Mujtaba, ...Computer Aided Chemical Engineering 9, 7-20, 2022202
4
2022
Economic model for lot-size determination in pharmaceutical injectable manufacturing
M Yamada, S Badr, S Fukuda, M Nakaya, Y Yoshioka, H SugiyamaJournal of Pharmaceutical Innovation 16, 38-52, 2021202
4
2021
Model-based comparison of batch and flow syntheses of an active pharmaceutical ingredient using heterogeneous hydrogenation
J Kim, H Yonekura, T Watanabe, S Yoshikawa, H Nakanishi, S Badr, ...Computers & Chemical Engineering 156, 10751, 2022202
4
2022
A systematic techno-economic approach to decide between continuous and batch operation modes for injectable manufacturing
M Yamada, S Badr, IA Udugama, S Fukuda, M Nakaya, Y Yoshioka, ...International Journal of Pharmaceutics 61, 1215, 2022202
3
2022
Agile Process Systems Engineering (PSE) education–2. How to teach to achieve desired outcomes mastery by graduates
DR Lewin, IT Cameron, EM Kondili, G Léonard, SS Mansouri, FG Martins, ...Computer Aided Chemical Engineering 51, 1675-1680, 2022202
3
2022
Design framework and tools for solid drug product manufacturing processes
K Matsunami, S Badr, H SugiyamaOptimization of Pharmaceutical Processes, 9-412, 2022202
3
2022
2
2022
Determination of critical decision points for COVID-19 measures in Japan
J Kim, K Matsunami, K Okamura, S Badr, H SugiyamaScientific Reports 11 (1), 16416, 010
2
2021