Author

Ling He

Johns hopkins School of Medicine - Cited by 4,078 - Metabolism/Signal Transduction

Biography

Dr. Ling He is an associate professor of pediatrics and pharmacology at the Johns Hopkins University School of Medicine. His research focuses on metabolism. Dr. He earned his M.D. from Third Military Medical University in Chongqin, China, and his Ph.D. from the University of Arkansas for Medical Sciences. 
Title
Cited by
Year
Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein
L He, A Sabet, S Djedjos, R Miller, X Sun, MA Hussain, S Radovick, ...Cell 137 (4), 635-646, 2009200
571
2009
Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation
J Wang, D Gallagher, LM DeVito, GI Cancino, D Tsui, L He, GM Keller, ...Cell stem cell 11 (1), 23-35, 2012201
472
2012
Metformin action: concentrations matter
L He, FE WondisfordCell metabolism 21 (2), 159-162, 2015201
409
2015
Metformin improves mitochondrial respiratory activity through activation of AMPK
Y Wang, H An, T Liu, C Qin, H Sesaki, S Guo, S Radovick, M Hussain, ...Cell reports 29 (6), 1511-1523. e5, 2019201
215
2019
Current understanding of metformin effect on the control of hyperglycemia in diabetes
H An, L HeThe Journal of endocrinology 228 (3), R97, 2016201
214
2016
CBP histone acetyltransferase activity regulates embryonic neural differentiation in the normal and Rubinstein-Taybi syndrome brain
J Wang, ICG Weaver, A Gauthier-Fisher, H Wang, L He, J Yeomans, ...Developmental cell 18 (1), 114-125, 2010201
210
2010
Low concentrations of metformin suppress glucose production in hepatocytes through AMP-activated protein kinase (AMPK)*♦
J Cao, S Meng, E Chang, K Beckwith-Fickas, L Xiong, RN Cole, ...Journal of Biological Chemistry 289 (30), 20435-20446, 2014201
188
2014
Metformin activates AMP-activated protein kinase by promoting formation of the αβγ heterotrimeric complex
S Meng, J Cao, Q He, L Xiong, E Chang, S Radovick, FE Wondisford, ...Journal of Biological Chemistry 290 (6), 3793-3802, 2015201
159
2015
Metformin acts on two different molecular pathways to enhance adult neural precursor proliferation/self-renewal and differentiation
M Fatt, K Hsu, L He, F Wondisford, FD Miller, DR Kaplan, J WangStem cell reports 5 (6), 988-995, 2015201
118
2015
Metformin and systemic metabolism
L HeTrends in Pharmacological Sciences 41 (11), 868-881, 2020202
94
2020
A murine neonatal model of necrotizing enterocolitis caused by anemia and red blood cell transfusions
K MohanKumar, K Namachivayam, T Song, B Jake Cha, A Slate, ...Nature communications 10 (1), 3494, 2019201
67
2019
Novel mechanism of Foxo1 phosphorylation in glucagon signaling in control of glucose homeostasis
Y Wu, Q Pan, H Yan, K Zhang, X Guo, Z Xu, W Yang, Y Qi, CA Guo, ...Diabetes 67 (11), 2167-2182, 2018201
63
2018
Insulin-like growth factor 1 mediates negative feedback to somatotroph GH expression via POU1F1/CREB binding protein interactions
CJ Romero, E Pine-Twaddell, DI Sima, RS Miller, L He, F Wondisford, ...Molecular and cellular biology 32 (21), 4258-4269, 2012201
59
2012
Endotoxemia-mediated activation of acetyltransferase P300 impairs insulin signaling in obesity
J Cao, J Peng, H An, Q He, T Boronina, S Guo, MF White, PA Cole, L HeNature Communications 8 (1), 131, 2017201
57
2017
Dose-dependent effects of alcohol on insulin signaling: partial explanation for biphasic alcohol impact on human health
L He, JC Marecki, G Serrero, FA Simmen, MJJ Ronis, TM BadgerMolecular endocrinology 21 (10), 21-2550, 2007200
54
2007
Transcriptional co-activator p300 maintains basal hepatic gluconeogenesis
L He, K Naik, S Meng, J Cao, AR Sidhaye, A Ma, S Radovick, ...Journal of Biological Chemistry 287 (38), 32069-32077, 2012201
49
2012
Control of Foxo1 gene expression by co-activator P300
AR Wondisford, L Xiong, E Chang, S Meng, DJ Meyers, M Li, PA Cole, ...Journal of Biological Chemistry 289 (7), 4326-4333, 2014201
47
2014
Activation of the cAMP-PKA pathway antagonizes metformin suppression of hepatic glucose production
L He, E Chang, J Peng, H An, SM McMillin, S Radovick, CA Stratakis, ...Journal of Biological Chemistry 291 (20), 10562-10570, 2016201
41
2016
PDK4 deficiency suppresses hepatic glucagon signaling by decreasing cAMP levels
BY Park, JH Jeon, Y Go, HJ Ham, JE Kim, EK Yoo, WH Kwon, NH Jeoung, ...Diabetes 67 (10), 2054-2068, 2018201
36
2018
IRS posttranslational modifications in regulating insulin signaling
J Peng, L HeJournal of molecular endocrinology 60 (1), R1-R8, 2018201
35
2018

Referred From: https://scholar.google.com/citations?user=UlKfKKUAAAAJ&hl=en

Cited by
Citations 4078
h-index 28
i10-index 41
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