Author

Shagufta Shafique

Quaid-i-Azam University, Islamabad - Cited by 197 - Structural Bioinformatics

Biography

He is working in National Center for Bioinformatics, Quaid-i-Azam University, Islamabad, Pakistan. some of his publications are Facile one-pot synthesis, butyrylcholinesterase and α-glucosidase inhibitory activities, structure–activity relationship, molecular docking and DNA–drug binding analysis of Meldrum’s acid derivatives , Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer , Structural characterization of β-catenin and RX-5902 binding to phospho-p68 RNA helicase by molecular dynamics simulation .
Title
Cited by
Year
Comparative in silico analyses of Cannabis sativa, Prunella vulgaris and Withania somnifera compounds elucidating the medicinal properties against rheumatoid arthritis
M Zaka, SA Sehgal, S Shafique, BH AbbasiJournal of Molecular Graphics and Modelling 74, 296-304, 2017201
28
2017
Repurposing FDA approved drugs as JNK3 inhibitor for prevention of neuroinflammation induced by MCAO in rats
Z Zulfiqar, FA Shah, S Shafique, A Alattar, T Ali, AM Alvi, S Rashid, S LiJournal of Inflammation Research, 1185-1205, 2020202
25
2020
Oats: A fodder of winter lean period
AM Haqqani, Z Ali, S Shafique, S Zahid, A BakhshAgridigest (Pakistan), 2003200
25
2003
Molecular modeling and docking analysis of CYP1A1 associated with head and neck cancer to explore its binding regions
SA Sehgal, RA Tahir, S Shafique, M Hassan, S RashidJ Theor Comput Sci 1 (112), 2, 2014201
24
2014
Inhibition of Janus kinases by tyrosine phosphorylation inhibitor, Tyrphostin AG-490
S Rashid, N Bibi, Z Parveen, S ShafiqueJournal of Biomolecular Structure and Dynamics 33 (11), 2368-2379, 2015201
18
2015
Structural basis for Cullins and RING component inhibition: Targeting E3 ubiquitin pathway conductors for cancer therapeutics
S Shafique, W Ali, S Kanwal, S RashidInternational journal of biological macromolecules 106, 532-543, 2018201
14
2018
Blockade of PDGFRβ circumvents resistance to MEK-JAK inhibition via intratumoral CD8+ T-cells infiltration in triple-negative breast cancer
M Kalimutho, D Sinha, D Mittal, S Srihari, D Nanayakkara, S Shafique, ...Journal of Experimental & Clinical Cancer Research 38 (1), 1-18, 2019201
13
2019
Elucidation, functional clustering and structural characterization of βTrCP1 substrates through a molecular dynamics study
S Shafique, S Younis, H Niaz, S RashidMolecular BioSystems 12 (7), 2233-2246, 2016201
11
2016
Antiviral drug acyclovir exhibits antitumor activity via targeting βTrCP1: Molecular docking and dynamics simulation study
S Shafique, S RashidJournal of Molecular Graphics and Modelling 72, 6-105, 2017201
9
2017
In silico identification of putative bifunctional Plk1 inhibitors by integrative virtual screening and structural dynamics approach
S Shafique, N Bibi, S RashidJournal of Theoretical Biology 388, 72-84, 2016201
9
2016
Structural basis of βTrCP1-associated GLI3 processing
S Shafique, S RashidScientific Reports 9 (1), 6865, 2019201
7
2019
Structural characterization of β-catenin and RX-5902 binding to phospho-p68 RNA helicase by molecular dynamics simulation
Structural characterization of β-catenin and RX-5902 binding to phospho-p8 RNA helicase by molecular dynamics simulationW Ali, S Shafique, S RashidProgress in Biophysics and Molecular Biology 140, 79-89, 2018201
6
2018
Facile one-pot synthesis, butyrylcholinesterase and α-glucosidase inhibitory activities, structure–activity relationship, molecular docking and DNA–drug binding analysis of …
H Mehfooz, A Saeed, M Faisal, FA Larik, U Muqadar, S Khatoon, ...Research on Chemical Intermediates 46, 2437-246, 2020202
5
2020
Structural basis for renal cancer by the dynamics of pVHL-dependent JADE1 stabilization and β-catenin regulation
S Shafique, S RashidProgress in Biophysics and Molecular Biology 145, 65-77, 01901
2
2019
E2UbcH5B-derived peptide ligands target HECT E3-E2 binding site and block the Ub-dependent SARS-CoV-2 egression: A computational study
S Zahid, M Gul, S Shafique, S RashidComputers in Biology and Medicine 46, 05660, 2022202
1
2022

Referred From: https://scholar.google.com.pk/citations?user=vfHCKDwAAAAJ&hl=en

Cited by
Citations 197
h-index 9
i10-index 8
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