Author

Kochat H

Director, University of TENNESSEE Health Science Center - Cited by 237 - manufacturing - chemistry - malyalam literature

Biography

Kochat H is working as a research scholar in BioNumerik Pharmaceuticals in USA. His research interest includes Wide range of publications like Compounds and methods for reducing undesired toxicity of chemotherapeutic agents and Compounds and methods for reducing undesired toxicity of chemotherapeutic agents.
Title
Cited by
Year
New approaches to drug discovery and development: a mechanism-based approach to pharmaceutical research and its application to BNP7787, a novel chemoprotective agent
FH Hausheer, H Kochat, AR Parker, D Ding, S Yao, SE Hamilton, ...Cancer chemotherapy and pharmacology 52, 3-15, 2003200
41
2003
Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of gamma-glutamyl transpeptidase
FH Hausheer, D Shanmugarajah, BD Leverett, X Chen, Q Huang, ...Cancer chemotherapy and pharmacology 65, 941-951, 2010201
23
2010
Mechanistic study of BNP7787-mediated cisplatin nephroprotection: modulation of human aminopeptidase N
FH Hausheer, AR Parker, PN Petluru, KW Jair, S Chen, Q Huang, X Chen, ...Cancer chemotherapy and pharmacology 67, 381-391, 111
20
2011
Monoazole ligand platinum analogs
Z Xiao, H Kochat, FH HausheerUS Patent 7,759,488, 2010201
17
2010
Analysis of BNP7787 thiol-disulfide exchange reactions in phosphate buffer and human plasma using microscale electrochemical high performance liquid chromatography
D Shanmugarajah, D Ding, Q Huang, X Chen, H Kochat, PN Petluru, ...Journal of Chromatography B 877 (10), 857-866, 2009200
16
2009
BNP7787-Mediated Modulation of Paclitaxel- and Cisplatin-Induced Aberrant Microtubule Protein Polymerization In vitro
AR Parker, PN Petluru, M Wu, M Zhao, H Kochat, FH HausheerMolecular cancer therapeutics 9 (9), 2558-2567, 2010201
12
2010
Cysteine specific targeting of the functionally distinct peroxiredoxin and glutaredoxin proteins by the investigational disulfide BNP7787
AR Parker, PN Petluru, VL Nienaber, J Badger, BD Leverett, K Jair, ...Molecules 20 (3), 4928-4950, 2015201
11
2015
11
2003
Process for synthesizing antifolates
Z Xiao, H KochatUS Patent App. /627,485, 2004200
10
2004
Process for coupling amino acids to an antifolate scaffold
H Kochat, Y WuUS Patent App. /4,660, 2003200
10
2003
Accumulation of BNP7787 in human renal proximal tubule cells
Accumulation of BNP8 in human renal proximal tubule cellsFH Hausheer, D Ding, D Shanmugarajah, BD Leverett, Q Huang, X Chen, ...Journal of pharmaceutical sciences 100 (9), 39-3984, 2011201
7
2011
C7-substituted camptothecin analogs
C-substituted camptothecin analogsK Narkunan, X Chen, H Kochat, F HausheerUS Patent ,68,496, 2010201
7
2010
Karenitecins: further developments with BNP1350, a novel, highly lipophilic, lactone stable camptothecin
F Hausheer, M Zhao, H Kochat, D Seetharamolo, D Murali, D Reddy, ...Proc Am Assoc Cancer Res 41, 213, 2000200
6
2000
Novel covalent modification of human anaplastic lymphoma kinase (ALK) and potentiation of crizotinib-mediated inhibition of ALK activity by BNP7787
AR Parker, PN Petluru, VL Nienaber, M Zhao, PY Ayala, J Badger, ...OncoTargets and therapy, 375-383, 2015201
6
2015
Stabilization of the Karenitecin® lactone by alpha-1 acid glycoprotein
S Yao, P Petluru, A Parker, D Ding, X Chen, Q Huang, H Kochat, ...Cancer Chemotherapy and Pharmacology 75, 719-728, 2015201
6
2015
BNP7787: A Novel chemoprotecting agent for platinum and taxane toxicity
F Hausheer, H Kochat, D Reddy, M Zhao, P Seetharamulu, S Yao, ...Proc Am Assoc Cancer Res 41, 769-770, 2000200
5
2000
Process for synthesizing L-γ-methylene glutamic acid and analogs
H Kochat, X Chen, Y Wu, Q Huang, J Wang, V GeruszUS Patent 6,977,311, 20020
5
2005
Comprehensive Comparative Study Using Ab Initio Computational Approaches on the Structures of Cisplatin, Oxaliplatin and BNP3029 (A Novel Substituted Cyano Ligand-based …
Comprehensive Comparative Study Using Ab Initio Computational Approaches on the Structures of Cisplatin, Oxaliplatin and BNP029 (A Novel Substituted Cyano Ligand-based …PNV Pavankumar, PY Ayala, AR Parker, M Zhao, K Jair, X Chen, ...J Phys Chem Biophys 4 (16), 2161-098.100016, 2014201
3
2014
Process for making camptothecin derivatives
Y Wu, K Narkunan, J Wang, H KochatUS Patent 7,00,24, 2006200
3
2006