Author

Guangrui Yang

University of Pennsylvania - Cited by 2,892 - prostaglandin circadian ppar nuclear receptor

Biography

Dr. Guangrui Yang received his MD from the Second Military Medical University and PhD in pathophysiology from Peking University, China. He trained as a postdoctoral fellow at the University of Utah where he revealed important roles of PPARgamma, a prostaglandin J2 receptor and antidiabetic drug target, in the regulation of circadian rhythms. He is currently a Research Assistant Professor of Pharmacology in the Institute for Translational Medicine and Therapeutics (ITMAT) at the University of Pennsylvania. He commences research encompassing both circadian clock and prostaglandin in cardiovascular pharmacology. He serves as an editor and a reviewer for several scientific journals.
Title
Cited by
Year
Circadian clock proteins regulate neuronal redox homeostasis and neurodegeneration
ES Musiek, MM Lim, G Yang, AQ Bauer, L Qi, Y Lee, JH Roh, ...The Journal of clinical investigation 123 (12), 5389-5400, 2013201
413
2013
Timing of expression of the core clock gene Bmal1 influences its effects on aging and survival
G Yang, L Chen, GR Grant, G Paschos, WL Song, ES Musiek, V Lee, ...Science Translational Medicine 8 (324), 324ra16-324ra16, 2016201
265
2016
Vascular PPARγ controls circadian variation in blood pressure and heart rate through Bmal1
N Wang, G Yang, Z Jia, H Zhang, T Aoyagi, S Soodvilai, JD Symons, ...Cell Metabolism 8 (6), 482-491, 2008200
260
2008
Circadian control of innate immunity in macrophages by miR-155 targeting Bmal1
AM Curtis, CT Fagundes, G Yang, EM Palsson-McDermott, P Wochal, ...Proceedings of the National Academy of Sciences 112 (23), 7231-7236, 2015201
259
2015
PPARs integrate the mammalian clock and energy metabolism
L Chen, G YangPPAR research 2014, 2014201
203
2014
Recent advances in circadian rhythms in cardiovascular system
L Chen, G YangFront. Pharmacol 6 (71), 2015201
179
2015
Prostanoids and Inflammatory Pain
L Chen, G Yang, T GrosserProstaglandins & Other Lipid Mediators, 2012201
137
2012
Antihypertensive effects of selective prostaglandin E2 receptor subtype 1 targeting
Y Guan, Y Zhang, J Wu, Z Qi, G Yang, D Dou, Y Gao, L Chen, X Zhang, ...The Journal of clinical investigation 117 (9), 2496-2505, 2007200
116
2007
Systemic PPARγ deletion impairs circadian rhythms of behavior and metabolism
G Yang, Z Jia, T Aoyagi, D McClain, RM Mortensen, T YangPLoS One 7 (8), e38117, 2012201
87
2012
A pilot characterization of the human chronobiome
C Skarke, NF Lahens, SD Rhoades, A Campbell, K Bittinger, A Bailey, ...Scientific reports 7 (1), 17141, 2017201
76
2017
Inactivation of the E-prostanoid 3 receptor attenuates the angiotensin II pressor response via decreasing arterial contractility
L Chen, Y Miao, Y Zhang, D Dou, L Liu, X Tian, G Yang, D Pu, X Zhang, ...Arteriosclerosis, thrombosis, and vascular biology 32 (12), 3024-3032, 2012201
58
2012
New Insights into the PPARγ Agonists for the Treatment of Diabetic Nephropathy
Z Jia, Y Sun, G Yang, A Zhang, S Huang, KM Heiney, Y ZhangPPAR research 2014, 2014201
57
2014
Induction of MIF expression by oxidized LDL via activation of NF-κB in vascular smooth muscle cells
L Chen, G Yang, X Zhang, J Wu, Q Gu, M Wei, J Yang, Y Zhu, Y GuanAtherosclerosis 207 (2), 428-433, 2009200
53
2009
Myeloid cell microsomal prostaglandin E synthase-1 fosters atherogenesis in mice
L Chen, G Yang, J Monslow, L Todd, DP Cormode, J Tang, GR Grant, ...Proceedings of the National Academy of Sciences 111 (18), 6828-6833, 2014201
51
2014
Cell selective cardiovascular biology of microsomal prostaglandin E synthase-1
L Chen, G Yang, X Xu, G Grant, JA Lawson, M Bohlooly-Y, GA FitzGeraldCirculation 127 (2), 233-243, 2013201
46
2013
An Update of Microsomal Prostaglandin E Synthase-1 and PGE2 Receptors in Cardiovascular Health and Diseases
G Yang, L ChenOxidative Medicine and Cellular Longevity 2016, 2016201
36
2016
Knitting up the raveled sleave of care
G Yang, G Paschos, AM Curtis, ES Musiek, SC McLoughlin, ...Science translational medicine 5 (212), 212rv3-212rv3, 2013201
35
2013
Rotenone protects against acetaminophen-induced kidney injury by attenuating oxidative stress and inflammation
H Hua, X Ge, M Wu, C Zhu, L Chen, G Yang, Y Zhang, S Huang, A Zhang, ...Kidney and Blood Pressure Research 43 (4), 1297-1309, 2018201
31
2018
Bmal1 Deletion in Myeloid Cells Attenuates Atherosclerotic Lesion Development and Restrains Abdominal Aortic Aneurysm Formation in Hyperlipidemic Mice
G Yang, J Zhang, T Jiang, J Monslow, S Tang, L Todd, E Puré, L Chen, ...Arteriosclerosis, Thrombosis, and Vascular Biology 40 (6), 1523-1532, 2020202
31
2020
Role of dihydroartemisinin in regulating prostaglandin E2 synthesis cascade and inflammation in endothelial cells
J Yin, W Xia, Y Zhang, G Ding, L Chen, G Yang, S Huang, Z Jia, A ZhangHeart and Vessels 33, 1411-1422, 2018201
24
2018

Referred From: https://scholar.google.co.in/citations?user=2TyV8RwAAAAJ&hl=en

Cited by
Citations 2892
h-index 24
i10-index 38
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