Author

Freitas-Junior LH

Institute of Biomedical Sciences, ICB, University of S

Biography

Dr. Freitas currently working as an eminent Faculty member at Department of Microbiology. He has published numerous research papers and articles in reputed journals and has various other achievements in the related studies. He has extended her valuable service towards the scientific community with his extensive research work. 
Title
Cited by
Year
UV-C (254 nm) lethal doses for SARS-CoV-2
CP Sabino, FP Sellera, DF Sales-Medina, RRG Machado, EL Durigon, ...Photodiagnosis and Photodynamic Therapy 32, 101995, 2020202
73
2020
Ag nanoparticles-based antimicrobial polycotton fabrics to prevent the transmission and spread of SARS-CoV-2
GC Tremiliosi, LGP Simoes, DT Minozzi, RI Santos, DCB Vilela, ...BioRxiv, 2020.06. 26.152520, 2020202
59
2020
Chroman-4-one derivatives targeting pteridine reductase 1 and showing anti-parasitic activity
F Di Pisa, G Landi, L Dello Iacono, C Pozzi, C Borsari, S Ferrari, ...Molecules 22 (3), 426, 2017201
44
2017
A comparative study of warheads for design of cysteine protease inhibitors
DG Silva, JFR Ribeiro, D De Vita, L Cianni, CH Franco, LH Freitas-Junior, ...Bioorganic & medicinal chemistry letters 27 (22), 5031-5035, 2017201
37
2017
Hydrocephalus and arthrogryposis in an immunocompetent mouse model of ZIKA teratogeny: A developmental study
J Xavier-Neto, M Carvalho, BS Pascoalino, AC Cardoso, ÂMS Costa, ...PLoS neglected tropical diseases 11 (2), e0005363, 2017201
37
2017
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections
P Linciano, CB Moraes, LM Alcantara, CH Franco, B Pascoalino, ...European Journal of Medicinal Chemistry 146, 423-434, 2018201
35
2018
Sofosbuvir inhibits yellow fever virus in vitro and in patients with acute liver failure
ÉA Mendes, DRB de Pilger, ACSS Nastri, F de Mello Malta, ...Annals of Hepatology 18 (6), 816-824, 2019201
33
2019
Drug discovery for Chagas disease: impact of different host cell lines on assay performance and hit compound selection
CH Franco, LM Alcântara, E Chatelain, L Freitas-Junior, CB MoraesTropical Medicine and Infectious Disease 4 (2), 82, 2019201
33
2019
From Live Cells to Caenorhabditis elegans: Selective Staining and Quantification of Lipid Structures Using a Fluorescent Hybrid Benzothiadiazole Derivative
AAR Mota, JR Correa, LP de Andrade, JAF Assumpção, ...ACS omega 3 (4), 3874-3881, 2018201
32
2018
Design, synthesis and antitrypanosomal activity of some nitrofurazone 1, 2, 4-triazolic bioisosteric analogues
FT Silva, CH Franco, DC Favaro, LH Freitas-Junior, CB Moraes, ...European Journal of Medicinal Chemistry 121, 553-560, 2016201
32
2016
Computer-aided discovery of two novel chalcone-like compounds active and selective against Leishmania infantum
MN Gomes, LM Alcântara, BJ Neves, CC Melo-Filho, LH Freitas-Junior, ...Bioorganic & medicinal chemistry letters 27 (11), 2459-2464, 2017201
30
2017
Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To Inhibit Trypanosoma brucei Pteridine Reductase in Support of Early-Stage Drug Discovery
P Linciano, A Dawson, I Pöhner, DM Costa, MS Sa, A Cordeiro-da-Silva, ...ACS omega 2 (9), 5666-5683, 2017201
29
2017
Crassiflorone derivatives that inhibit Trypanosoma brucei glyceraldehyde-3-phosphate dehydrogenase (TbGAPDH) and Trypanosoma cruzi trypanothione reductase (TcTR) and display …
E Uliassi, G Fiorani, RL Krauth-Siegel, C Bergamini, R Fato, G Bianchini, ...European Journal of Medicinal Chemistry 141, 138-148, 2017201
26
2017
Non-toxic dimeric peptides derived from the bothropstoxin-I are potent SARS-CoV-2 and papain-like protease inhibitors
MCLC Freire, GD Noske, NV Bitencourt, PRS Sanches, NA Santos-Filho, ...Molecules 26 (16), 4896, 2021202
23
2021
Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening
CC Melo-Filho, RC Braga, EN Muratov, CH Franco, CB Moraes, ...European journal of medicinal chemistry 163, 649-659, 2019201
22
2019
Synthesis and structure-activity relationship of nitrile-based cruzain inhibitors incorporating a trifluoroethylamine-based P2 amide replacement
JC Gomes, L Cianni, J Ribeiro, F dos Reis Rocho, SCM Silva, PHJ Batista, ...Bioorganic & Medicinal Chemistry 27 (22), 115083, 202
19
2019
Discovery of clinically approved drugs capable of inhibiting SARS-CoV-2 in vitro infection using a phenotypic screening strategy and network-analysis to predict …
DF Sales-Medina, LRP Ferreira, LMD Romera, KR Gonçalves, ...BioRxiv, 2020.07. 09.196337, 2020202
18
2020
Accelerating drug discovery efforts for trypanosomatidic infections using an integrated transnational academic drug discovery platform
CB Moraes, G Witt, M Kuzikov, B Ellinger, T Calogeropoulou, KC Prousis, ...SLAS DISCOVERY: Advancing Life Sciences R&D 24 (3), 346-361, 2019201
18
2019
Highly improved antiparasitic activity after introduction of an N-benzylimidazole moiety on protein farnesyltransferase inhibitors
D Bosc, E Mouray, S Cojean, CH Franco, PM Loiseau, LH Freitas-Junior, ...European journal of medicinal chemistry 109, 3-186, 2016201
17
2016
Development of a Focused Library of Triazole‐Linked Privileged‐Structure‐Based Conjugates Leading to the Discovery of Novel Phenotypic Hits against Protozoan Parasitic Infections
E Uliassi, L Piazzi, F Belluti, A Mazzanti, M Kaiser, R Brun, CB Moraes, ...ChemMedChem 13 (7), 678-683, 2018201
16
2018

Referred From: https://scholar.google.ch/citations?user=OPRUxcoAAAAJ&hl=en

Cited by
Citations 6080
h-index 37
i10-index 67
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