Author

Robert Dixon Phillips

Professor of Chemistry and of Biochemistry and Molecular Biology - Cited by 8,228 - Bio-organic Chemistry

Biography

Robert Dixon Phillips is working as a Professor of Chemistry and of Biochemistry and Molecular Biology in The University of Georgia, USA. His research interests are chemistry and bio-organic. His publication in google scholar "Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4".
Title
Cited by
Year
Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4
M Venkatesh, S Mukherjee, H Wang, H Li, K Sun, AP Benechet, Z Qiu, ...Immunity 41 (2), 296-310, 2014201
722
2014
The entropic force generated by intrinsically disordered segments tunes protein function
ND Keul, K Oruganty, ET Schaper Bergman, NR Beattie, WE McDonald, ...Nature 563 (7732), 584-588, 2018201
109
2018
Controlling substrate specificity and stereospecificity of alcohol dehydrogenases
CM Nealon, MM Musa, JM Patel, RS PhillipsAcs Catalysis 5 (4), 2100-2114, 2015201
95
2015
Chemistry and diversity of pyridoxal-5′-phosphate dependent enzymes
RS PhillipsBiochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1854 (9), 1167-1174, 2015201
75
2015
Structure and mechanism of kynureninase
RS PhillipsArchives of biochemistry and biophysics 544, 69-74, 2014201
50
2014
Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase mutants with improved racemization activity
MM Musa, JM Patel, CM Nealon, CS Kim, RS Phillips, I KarumeJournal of Molecular Catalysis B: Enzymatic 115, 155-159, 2015201
33
2015
Modulation of enzyme activity in the kynurenine pathway by kynurenine monooxygenase inhibition
RS Phillips, EC Iradukunda, T Hughes, JP BowenFrontiers in molecular biosciences 6, 3, 2019201
31
2019
Ground-state destabilization by Phe-448 and Phe-449 contributes to tyrosine phenol-lyase catalysis
RS Phillips, A Vita, JB Spivey, AP Rudloff, MD Driscoll, S HayACS Catalysis 6 (10), 6770-6779, 2016201
22
2016
Aromatic amino acid metabolism
Q Han, RS Phillips, J LiFrontiers in molecular biosciences 6, 22, 2019201
18
2019
The kynurenine pathway and kynurenine 3-monooxygenase inhibitors
TD Hughes, OF Güner, EC Iradukunda, RS Phillips, JP BowenMolecules 27 (1), 273, 2022202
15
2022
I86A/C295A mutant secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus has broadened substrate specificity for aryl ketones
CM Nealon, TP Welsh, CS Kim, RS PhillipsArchives of biochemistry and biophysics 606, 1-6, 2016201
15
2016
Substrate and inhibitor specificity of kynurenine monooxygenase from Cytophaga hutchinsonii
RS Phillips, AD Anderson, HG Gentry, OF Güner, JP BowenBioorganic & medicinal chemistry letters 27 (8), 1705-1708, 2017201
14
2017
The role of substrate strain in the mechanism of the carbon–carbon lyases
RS Phillips, TV Demidkina, NG FaleevBioorganic chemistry 57, 198-205, 2014201
11
2014
Oxygen reactivity with pyridoxal 5′-phosphate enzymes: biochemical implications and functional relevance
G Bisello, C Longo, G Rossignoli, RS Phillips, M BertoldiAmino Acids 52, 89-15, 2020202
10
2020
New cases that expand the genotypic and phenotypic spectrum of Congenital NAD Deficiency Disorder
JO Szot, A Slavotinek, K Chong, O Brandau, M Nezarati, ...Human mutation 42 (7), 862-876, 2021202
9
2021
The crystal structure of Proteus vulgaris tryptophan indole-lyase complexed with oxindolyl-L-alanine: Implications for the reaction mechanism
RS Phillips, AA Buisman, S Choi, A Hussaini, ZA WoodActa Crystallographica Section D: Structural Biology 74 (), 74-759, 20120
8
2018
Pressure and temperature effects on the formation of aminoacrylate intermediates of tyrosine phenol-lyase demonstrate reaction dynamics
RS Phillips, S Craig, A Kovalevsky, O Gerlits, K Weiss, AI Iorgu, DJ Heyes, ...ACS Catalysis 10 (3), 1692-1703, 2019201
8
2019