Author

Qiang Chen

Professor, Arizona State University - Cited by 5,208 - Molecular Biology - Biochemistry - Vaccine - Therapeutics - Plant Biology

Biography

Qiang “Shawn” Chen is a molecular biologist who specializes in developing novel human therapeutics and vaccines in plants to combat infectious diseases, cancer, and biological warfare agents. His research aims to ameliorate diseases and improve human health, as well as to contribute new knowledge to the basic understanding of how gene expression and protein modification are regulated in plants.
Title
Cited by
Year
Virus-like particles that display Zika virus envelope protein domain III induce potent neutralizing immune responses in mice
M Yang, H Lai, H Sun, Q ChenScientific Reports 7 (1), 7679, 2017201
120
2017
Immunization of Zika virus envelope protein domain III induces specific and neutralizing immune responses against Zika virus
M Yang, M Dent, H Lai, H Sun, Q ChenVaccine 35 (33), 4287-4294, 2017201
98
2017
Plant‐produced Zika virus envelope protein elicits neutralizing immune responses that correlate with protective immunity against Zika virus in mice
M Yang, H Sun, H Lai, J Hurtado, Q ChenPlant biotechnology journal 16 (2), 5-580, 2018201
72
2018
High level production of monoclonal antibodies using an optimized plant expression system
AG Diamos, JGL Hunter, MD Pardhe, SH Rosenthal, H Sun, BC Foster, ...Frontiers in Bioengineering and Biotechnology 7, 472, 2020202
69
2020
Role of contacts in long-range protein conductance
SL Bintian Zhang, Weisi Song, Pei Pang, Huafang Lai, Qiang Chen, Peiming ZhangPNAS, 201967201
67
2019
Plant-produced anti-dengue virus monoclonal antibodies exhibit reduced antibody-dependent enhancement of infection activity
M Dent, J Hurtado, AM Paul, H Sun, H Lai, M Yang, A Esqueda, F Bai, ...Journal of General Virology 97 (12), 3280-3290, 2016201
64
2016
Development of antibody therapeutics against flaviviruses
H Sun, Q Chen, H LaiInternational journal of molecular sciences 19 (1), 54, 2017201
63
2017
In vitro and in vivo efficacy of anti‐chikungunya virus monoclonal antibodies produced in wild‐type and glycoengineered N. benthamiana plants
J Hurtado, D Acharya, H Lai, H Sun, S Kallolimath, H Steinkellner, F Bai, ...Plant Biotechnology Journal, 201951201
51
2019
Highly active engineered IgG3 antibodies against SARS-CoV-2
S Kallolimath, L Sun, Q .....Chen, H SteinkellnerProceedings of the National Academy of Sciences 118 (42), e2107249118, 2021202
44
2021
A plant-produced vaccine protects mice against lethal West Nile virus infection without enhancing Zika or dengue virus infectivity
H Lai, AM Paul, H Sun, J He, M Yang, F Bai, Q ChenVaccine 36 (14), 1846-1852, 2018201
40
2018
Codelivery of improved immune complex and virus-like particle vaccines containing Zika virus envelope domain III synergistically enhances immunogenicity
AG Diamos, MD Pardhe, H Sun, JGL Hunter, T Mor, L Meador, ...Vaccine 38 (18), 3455-3463, 2020202
23
2020
Hydrophobin-Protein A Fusion Protein Produced in Plants Efficiently Purified an Anti-West Nile Virus Monoclonal Antibody from Plant Extracts via Aqueous Two-Phase Separation
C Jugler, J Joensuu, Q ChenInternational Journal of Molecular Sciences 21 (6), 2140, 2020202
17
2020
Molecular Pharming: Applications, Challenges and Emerging Areas
AR Kermode, L JiangJohn Wiley & Sons, 2018201
16
2018
Development of plant-made monoclonal antibodies against viral infections
Q ChenCurrent Opinion in Virology 52, 148-0, 2022202
16
2022
SARS-CoV-2 Spike Protein-Induced Interleukin 6 Signaling Is Blocked by a Plant-Produced Anti-Interleukin 6 Receptor Monoclonal Antibody
C Jugler, H Sun, Q ChenVaccines 9 (11), 65, 2021202
13
2021
Recombinant Therapeutic Molecules Produced in Plants
Q ChenAdvances in Botanical Research 86, 207-244, 2018201
10
2018
A highly expressing, soluble, and stable plant-made IgG fusion vaccine strategy enhances antigen immunogenicity in mice without adjuvant
AG Diamos, MD Pardhe, H Sun, JGL Hunter, J Kilbourne, Q Chen, ...Frontiers in immunology 11, 576012, 2020202
9
2020
Potential for a Plant-Made SARS-CoV-2 Neutralizing Monoclonal Antibody as a Synergetic Cocktail Component
C Jugler, H Sun, F Grill, K Kibler, A Esqueda, H Lai, Y Li, D Lake, Q ChenVaccines 10 (5), 772, 2022202
9
2022
Development and expression of subunit vaccines against viruses in plants
A Esqueda, Q ChenViruses as Therapeutics: Methods and Protocols, 25-3, 2021202
8
2021
Design and expression of a bispecific antibody against dengue and chikungunya virus in plants.
A Esqueda, C Jugler, Q ChenMethods in enzymology 660, 223-238, 2021202
7
2021

Referred From: https://scholar.google.com/citations?user=UJVBYAIAAAAJ&hl=en

Cited by
Citations 5208
h-index 38
i10-index 57
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