Author

Dmitri Simberg

University of Colorado Anschutz Medical Campus - Cited by 5,271 - Drug delivery - immune recognition of nanoparticles - lipid and iron oxide nanoparticles

Biography

 Dmitri Simberg has been working in the Moores UCSD Cancer Center, in University of California which is located in USA one of the publications are Has the Time for In silico Design of Nanomedicines Finally Arrived?
Title
Cited by
Year
Immunoglobulin deposition on biomolecule corona determines complement opsonization efficiency of preclinical and clinical nanoparticles
VP Vu, GB Gifford, F Chen, H Benasutti, G Wang, EV Groman, ...Nature nanotechnology 14 (3), 260-268, 2019201
187
2019
Roadmap and strategy for overcoming infusion reactions to nanomedicines
J Szebeni, D Simberg, Á González-Fernández, Y Barenholz, ...Nature nanotechnology 13 (12), 1100-1108, 2018201
138
2018
The interplay between blood proteins, complement, and macrophages on nanomedicine performance and responses
SM Moghimi, D Simberg, T Skotland, A Yaghmur, AC HunterJournal of Pharmacology and Experimental Therapeutics 370 (3), 581-592, 2019201
51
2019
Nanoparticle transport pathways into tumors
SM Moghimi, D SimbergJournal of Nanoparticle Research 20 (6), 169, 2018201
51
2018
Complement activation by drug carriers and particulate pharmaceuticals: Principles, challenges and opportunities
SM Moghimi, D Simberg, E Papini, ZS FarhangraziAdvanced drug delivery reviews 157, 83-95, 2020202
35
2020
Preclinical applications of multi-platform imaging in animal models of cancer
NJ Serkova, K Glunde, CR Haney, M Farhoud, A De Lille, EF Redente, ...Cancer research 81 (5), 1189-1200, 2021202
26
2021
Translational gaps in animal models of human infusion reactions to nanomedicines
SM Moghimi, D SimbergNanomedicine 13 (9), 973-975, 2018201
23
2018
Complement therapeutics meets nanomedicine: overcoming human complement activation and leukocyte uptake of nanomedicines with soluble domains of CD55
G Gifford, VP Vu, NK Banda, VM Holers, G Wang, EV Groman, D Backos, ...Journal of Controlled Release 302, 181-189, 2019201
21
2019
Feraheme (ferumoxytol) is recognized by proinflammatory and anti-inflammatory macrophages via scavenger receptor type AI/II
G Wang, NJ Serkova, EV Groman, RI Scheinman, D SimbergMolecular pharmaceutics 16 (10), 4274-4281, 2019201
21
2019
Complement opsonization of nanoparticles: Differences between humans and preclinical species
Y Li, G Wang, L Griffin, NK Banda, LM Saba, EV Groman, R Scheinman, ...Journal of Controlled Release 338, 548-556, 2021202
17
2021
Targeted intracellular delivery of trastuzumab using designer phage lambda nanoparticles alters cellular programs in human breast cancer cells
A Catala, M Dzieciatkowska, G Wang, A Gutierrez-Hartmann, D Simberg, ...ACS nano 15 (7), 11789-11805, 2021202
14
2021
Pharmacokinetic analysis reveals limitations and opportunities for nanomedicine targeting of endothelial and extravascular compartments of tumours
MJ Benchimol, D Bourne, SM Moghimi, D SimbergJournal of drug targeting 27 (5-6), 690-698, 2019201
13
2019
Lipid nanoparticle formulation of niclosamide (nano NCM) effectively inhibits SARS-CoV-2 replication in vitro
G Wang, H Gaikwad, MK McCarthy, M Gonzalez-Juarrero, Y Li, ...Precision nanomedicine 4 (1), 724, 2021202
10
2021
Liposomal extravasation and accumulation in tumors as studied by fluorescence microscopy and imaging depend on the fluorescent label
G Wang, M Zannikou, L Lofchy, Y Li, H Gaikwad, IV Balyasnikova, ...ACS nano 15 (7), 11880-11890, 2021202
10
2021
Complement inhibitors block complement C3 opsonization and improve targeting selectivity of nanoparticles in blood
H Gaikwad, Y Li, G Gifford, E Groman, NK Banda, L Saba, R Scheinman, ...Bioconjugate chemistry 31 (7), 1844-1856, 2020202
10
2020
Accelerated blood clearance of antibodies by nanosized click antidotes
WJ Smith, G Wang, H Gaikwad, VP Vu, E Groman, DWA Bourne, ...ACS nano 12 (12), 12523-12532, 2018201
10
2018
Dendrimer end-terminal motif-dependent evasion of human complement and complement activation through IgM hitchhiking
LP Wu, M Ficker, JB Christensen, D Simberg, PN Trohopoulos, ...Nature communications 12 (1), 4858, 2021202
9
2021
Pro-inflammatory concerns with lipid nanoparticles
SM Moghimi, D SimbergMolecular Therapy 30 (6), 2109-2110, 2022202
8
2022