Author

Delphine Denoyer

Research Fellow, Olivia Newton-John Cancer Research Institute - Cited by 2,936 - Cancer Research - Breast Cancer Metastasis - Translational Research - Metallomics - PET Imaging

Biography

Knowledge of the molecular profile of a tumor not only guides clinical decisions for optimal treatment but can be harnessed also to monitor treatment response objectively. In this respect, theranostic approaches for the diagnosis and treatment of a variety of tumor types are rapidly gaining momentum. By combining diagnostic imaging modalities with therapeutic interventions directed against the same molecular target, theranostics enables selection of patients more likely to respond to a specific therapy and consequently improves the therapeutic/toxicity ratio while avoiding unnecessary treatment
Title
Cited by
Year
Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
J Stagg, U Divisekera, N McLaughlin, J Sharkey, S Pommey, D Denoyer, ...Proceedings of the National Academy of Sciences 107 (4), 1547-1552, 2010201
627
2010
Targeting copper in cancer therapy: ‘Copper That Cancer’
D Denoyer, S Masaldan, S La Fontaine, MA CaterMetallomics 7 (11), 1459-1476, 2015201
569
2015
Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis
S Masaldan, SAS Clatworthy, C Gamell, PM Meggyesy, AT Rigopoulos, ...Redox biology 14, 100-115, 2018201
252
2018
Copper Complexes in Cancer Therapy.
D Denoyer, SAS Clatworthy, MA CaterMetal ions in life sciences 18, 2018201
96
2018
PET imaging of tumours with a 64 Cu labeled macrobicyclic cage amine ligand tethered to Tyr 3-octreotate
BM Paterson, P Roselt, D Denoyer, C Cullinane, D Binns, W Noonan, ...Dalton Transactions 43 (3), 1386-1396, 2014201
88
2014
Integrin‐dependent response to laminin‐511 regulates breast tumor cell invasion and metastasis
N Kusuma, D Denoyer, JA Eble, RP Redvers, BS Parker, R Pelzer, ...International journal of cancer 130 (3), 555-566, 2012201
87
2012
Neoadjuvant neratinib promotes ferroptosis and inhibits brain metastasis in a novel syngeneic model of spontaneous HER2+ ve breast cancer metastasis
A Nagpal, RP Redvers, X Ling, S Ayton, M Fuentes, E Tavancheh, I Diala, ...Breast Cancer Research 21 (1), 1-19, 2019201
85
2019
High-contrast PET of melanoma using 18F-MEL050, a selective probe for melanin with predominantly renal clearance
D Denoyer, I Greguric, P Roselt, OC Neels, N Aide, SR Taylor, A Katsifis, ...Journal of Nuclear Medicine 51 (3), 441-447, 2010201
73
2010
Discovery of [18F]N-(2-(Diethylamino)ethyl)-6-fluoronicotinamide: A Melanoma Positron Emission Tomography Imaging Radiotracer with High Tumor to Body …
I Greguric, SR Taylor, D Denoyer, P Ballantyne, P Berghofer, P Roselt, ...Journal of medicinal chemistry 52 (17), 5299-5302, 2009200
65
2009
[10]-gingerol induces apoptosis and inhibits metastatic dissemination of triple negative breast cancer in vivo
ACBM Martin, AM Fuzer, AB Becceneri, JA da Silva, R Tomasin, ...Oncotarget 8 (42), 72260, 2017201
63
2017
Gallium-68 complex of a macrobicyclic cage amine chelator tethered to two integrin-targeting peptides for diagnostic tumor imaging
MT Ma, OC Neels, D Denoyer, P Roselt, JA Karas, DB Scanlon, JM White, ...Bioconjugate chemistry 22 (10), 2093-2103, 2011201
59
2011
Copper as a target for prostate cancer therapeutics: copper-ionophore pharmacology and altering systemic copper distribution
D Denoyer, HB Pearson, SAS Clatworthy, ZM Smith, PS Francis, ...Oncotarget 7 (24), 37064, 2016201
58
2016
Analysis of 177Lu-DOTA-octreotate therapy–induced DNA damage in peripheral blood lymphocytes of patients with neuroendocrine tumors
D Denoyer, P Lobachevsky, P Jackson, M Thompson, OA Martin, ...Journal of Nuclear Medicine 56 (4), 505-511, 2015201
54
2015
Improved detection of regional melanoma metastasis using 18F-6-fluoro-N-[2-(diethylamino) ethyl] pyridine-3-carboxamide, a melanin-specific PET probe, by perilesional …
D Denoyer, T Potdevin, P Roselt, OC Neels, L Kirby, I Greguric, A Katsifis, ...Journal of Nuclear Medicine 52 (1), 115-122, 2011201
41
2011
Tumour but not stromal expression of β3 integrin is essential, and is required early, for spontaneous dissemination of bone‐metastatic breast cancer
RZ Carter, KC Micocci, A Natoli, RP Redvers, S Paquet‐Fifield, ...The Journal of pathology 235 (5), 760-772, 2015201
39
2015
Bifunctional aptamer–doxorubicin conjugate crosses the blood–brain barrier and selectively delivers its payload to EpCAM-positive tumor cells
J Macdonald, D Denoyer, J Henri, A Jamieson, IJG Burvenich, N Pouliot, ...nucleic acid therapeutics 30 (2), 117-128, 2020202
38
2020
Copper accumulation in senescent cells: Interplay between copper transporters and impaired autophagy
S Masaldan, SAS Clatworthy, C Gamell, ZM Smith, PS Francis, D Denoyer, ...Redox biology 16, 322-331, 2018201
37
2018
Heterogeneous copper concentrations in cancerous human prostate tissues
D Denoyer, SAS Clatworthy, S Masaldan, PM Meggyesy, MA CaterThe Prostate 75 (14), 1510-1517, 2015201
34
2015
Foxp3 expression in macrophages associated with RENCA tumors in mice
C Devaud, CSM Yong, LB John, JA Westwood, CPM Duong, CM House, ...PloS one 9 (9), e108670, 2014201
29
2014
Radiosynthesis and Biological Evaluation of l- and d-S-(3-[18F]Fluoropropyl)homocysteine for Tumor Imaging Using Positron Emission Tomography
T Bourdier, R Shepherd, P Berghofer, T Jackson, CJR Fookes, D Denoyer, ...Journal of medicinal chemistry 54 (6), 1860-1870, 2011201
28
2011

Referred From: https://scholar.google.com/citations?hl=en&user=n68latAAAAAJ

Cited by
Citations 2936
h-index 26
i10-index 40
Open Access Journals