Author

Bhaskar Ghoshal

ohio state university - Cited by 16,241 - cancer biology - hepatocellular cancer - microrna - dna methylation

Biography

A female patient, aged about 85 years, presented with a huge abdominal swelling which was bulging with coughing. An infra-umbilical scar was noticed. It was diagnosed as a case of strangulated of incisional hernia. There was evident necrosed skin at the middle of the swelling with contents exposed
Title
Cited by
Year
ERK activation globally downregulates miRNAs through phosphorylating exportin-5
HL Sun, R Cui, JK Zhou, K Teng, YH Hsiao, K Nakanishi, M Fassan, Z Luo, ...Cancer cell 30 (5), 723-736, 2016201
129
2016
Blocking the CCL2–CCR2 axis using CCL2-neutralizing antibody is an effective therapy for hepatocellular cancer in a mouse model
KY Teng, J Han, X Zhang, SH Hsu, S He, NA Wani, JM Barajas, ...Molecular cancer therapeutics 16 (2), 312-322, 2017201
114
2017
Mouse models of acute and chronic hepacivirus infection
E Billerbeck, R Wolfisberg, U Fahnøe, JW Xiao, C Quirk, JM Luna, ...Science 357 (6347), 204-208, 2017201
106
2017
Recent developments and therapeutic strategies against hepatocellular carcinoma
M Yarchoan, P Agarwal, A Villanueva, S Rao, LA Dawson, T Karasic, ...Cancer research 79 (17), 4326-4330, 2019201
105
2019
Argonaute CLIP defines a deregulated miR-122-bound transcriptome that correlates with patient survival in human liver cancer
JM Luna, JM Barajas, K Teng, HL Sun, MJ Moore, CM Rice, RB Darnell, ...Molecular cell 67 (3), 400-410. e7, 2017201
73
2017
The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer
JM Barajas, R Reyes, MJ Guerrero, ST Jacob, T Motiwala, K GhoshalScientific Reports 8 (1), 9105, 2018201
66
2018
Sorafenib and 2-deoxyglucose synergistically inhibit proliferation of both sorafenib-sensitive and-resistant HCC cells by inhibiting ATP production
R Reyes, NA Wani, K Ghoshal, ST Jacob, T MotiwalaGene Expression The Journal of Liver Research 17 (2), 129-140, 2017201
50
2017
Extracellular mRNA detected by molecular beacons in tethered lipoplex nanoparticles for diagnosis of human hepatocellular carcinoma
X Wang, KJ Kwak, Z Yang, A Zhang, X Zhang, R Sullivan, D Lin, RL Lee, ...PloS one 13 (6), e0198552, 2018201
47
2018
miRNA-122 protects mice and human hepatocytes from acetaminophen toxicity by regulating cytochrome P450 family 1 subfamily A member 2 and family 2 subfamily E member 1 expression
V Chowdhary, K Teng, S Thakral, B Zhang, C Lin, N Wani, ...The American journal of pathology 187 (12), 2758-2774, 2017201
40
2017
Regulation of hepatic glutamine metabolism by miR-122
D Sengupta, T Cassel, K Teng, M Aljuhani, VK Chowdhary, P Hu, ...Molecular metabolism 34, 174-186, 2020202
31
2020
Reprogramming of glucose metabolism by zerumbone suppresses hepatocarcinogenesis
NA Wani, B Zhang, K Teng, JM Barajas, T Motiwala, P Hu, L Yu, ...Molecular Cancer Research 16 (2), 256-268, 2018201
30
2018
Hypoxia-inducible factor–1α–dependent induction of miR122 enhances hepatic ischemia tolerance
C Ju, M Wang, E Tak, B Kim, C Emontzpohl, Y Yang, X Yuan, H Kutay, ...The Journal of Clinical Investigation 131 (7), 2021202
28
2021
A comprehensive analysis of argonaute-CLIP data identifies novel, conserved and species-specific targets of miR-21 in human liver and hepatocellular carcinoma
AB Koenig, JM Barajas, MJ Guerrero, K GhoshalInternational journal of molecular sciences 19 (3), 851, 2018201
26
2018
Transcriptomics-based drug repurposing approach identifies novel drugs against sorafenib-resistant hepatocellular carcinoma
K Regan-Fendt, D Li, R Reyes, L Yu, NA Wani, P Hu, ST Jacob, ...Cancers 12 (10), 2730, 2020202
22
2020
Ibrutinib Potentiates Antihepatocarcinogenic Efficacy of Sorafenib by Targeting EGFR in Tumor Cells and BTK in Immune Cells in the Stroma
CH Lin, KH Elkholy, NA Wani, D Li, P Hu, JM Barajas, L Yu, X Zhang, ...Molecular cancer therapeutics (2), 384-396, 2020202
19
2020
METTL3 regulates liver homeostasis, hepatocyte ploidy, and circadian rhythm–controlled gene expression in mice
JM Barajas, CH Lin, HL Sun, F Alencastro, AC Zhu, M Aljuhani, L Navari, ...The American Journal of Pathology 192 (1), 56-71, 2022202
18
2022
Intra-tumoral delivery of IL-27 using adeno-associated virus stimulates anti-tumor immunity and enhances the efficacy of immunotherapy
A Hu, M Ding, J Zhu, JQ Liu, X Pan, K Ghoshal, XF BaiFrontiers in Cell and Developmental Biology 8, 210, 2020202
16
2020
Down-regulation of micro-RNA-1 (miR-1) in lung cancer. Suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1.
MW Nasser, J Datta, G Nuovo, H Kutay, T Motiwala, S Majumder, B Wang, ...The Journal of Biological Chemistry 23 (33), 1245, 2018201
9
2018
Role of b cell lymphoma 2 in the regulation of liver fibrosis in mir-122 knockout mice
KY Teng, JM Barajas, P Hu, ST Jacob, K GhoshalBiology 9 (7), 157, 2020202
8
2020