Author

George S Vassiliou

Professor of Haematological Medicine, University of Cambridge & Cambridge Stem Cell Institute - Cited by 16,298 - Haematology - Leukaemia - Clonal Haematopoiesis

Biography

George Vassiliou is Professor of Haematological Medicine at the University of Cambridge, Cancer Research UK Senior Fellow and Consultant Haematologist at Cambridge University Hospitals. He studied Medicine at the Royal London Hospital and trained as a Haematologist in London and Cambridge. He obtained his PhD from the University of Cambridge in 2005 and went on to investigate the pathogenesis of acute myeloid leukaemia as a Cancer Research UK Clinician Scientist in Allan Bradley’s lab at the Wellcome Sanger Institute.  
Title
Cited by
Year
Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia
E Yankova, W Blackaby, M Albertella, J Rak, E De Braekeleer, ...Nature 593 (7860), 597-601, 2021202
392
2021
METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation
EA Orellana, Q Liu, E Yankova, M Pirouz, E De Braekeleer, W Zhang, ...Molecular cell 81 (16), 3323-3338. e14, 2021202
118
2021
Clonal dynamics of haematopoiesis across the human lifespan
E Mitchell, M Spencer Chapman, N Williams, KJ Dawson, N Mende, ...Nature 606 (7913), 343-350, 2022202
117
2022
The longitudinal dynamics and natural history of clonal haematopoiesis
MA Fabre, JG de Almeida, E Fiorillo, E Mitchell, A Damaskou, J Rak, ...Nature 606 (7913), 335-342, 2022202
97
2022
Genome-wide analyses of 200,453 individuals yield new insights into the causes and consequences of clonal hematopoiesis
SP Kar, PM Quiros, M Gu, T Jiang, J Mitchell, R Langdon, V Iyer, ...Nature Genetics 54 (8), 1155-1166, 2022202
63
2022
The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice
Y Yura, E Miura-Yura, Y Katanasaka, KD Min, N Chavkin, AH Polizio, ...Circulation research 129 (6), 684-698, 2021202
32
2021
KAT7 is a genetic vulnerability of acute myeloid leukemias driven by MLL rearrangements
YZ Au, M Gu, E De Braekeleer, M Gozdecka, D Aspris, Y Tarumoto, ...Leukemia 35 (4), 1012-1022, 2021202
23
2021
Clinical relevance of clonal hematopoiesis in persons aged≥ 80 years
M Rossi, M Meggendorfer, M Zampini, M Tettamanti, E Riva, E Travaglino, ...Blood, The Journal of the American Society of Hematology 138 (21), 2093-2105, 2021202
19
2021
TET2 and DNMT3A Mutations Exert Divergent Effects on DNA Repair and Sensitivity of Leukemia Cells to PARP Inhibitors
S Maifrede, BV Le, M Nieborowska-Skorska, K Golovine, K Sullivan-Reed, ...Cancer research 81 (19), 5089-5101, 2021202
17
2021
Venetoclax synergizes with gilteritinib in FLT3 wild-type high-risk acute myeloid leukemia by suppressing MCL-1
M Janssen, C Schmidt, PM Bruch, MF Blank, C Rohde, A Waclawiczek, ...Blood, The Journal of the American Society of Hematology 140 (24), 2594-2610, 2022202
15
2022
Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression
H Yun, N Narayan, S Vohra, G Giotopoulos, A Mupo, P Madrigal, D Sasca, ...Nature genetics 53 (10), 43-55, 2021202
14
2021
Early detection of T-cell lymphoma with T follicular helper phenotype by RHOA mutation analysis
R Dobson, PY Du, L Rásó-Barnett, WQ Yao, Z Chen, C Casa, ...Haematologica 107 (2), 489, 2022202
12
2022
Controlled masking and targeted release of redox-cycling ortho-quinones via a C–C bond-cleaving 1,6-elimination
L Dunsmore, CD Navo, J Becher, EG de Montes, A Guerreiro, E Hoyt, ...Nature Chemistry 14 (7), 754-765, 2022202
11
2022
A macaque clonal hematopoiesis model demonstrates expansion of TET2-disrupted clones and utility for testing interventions
TH Shin, Y Zhou, S Chen, S Cordes, MZ Grice, X Fan, BC Lee, ...Blood, The Journal of the American Society of Hematology 140 (16), 1774-178, 2022202
9
2022
STAT1 is essential for HSC function and maintains MHCIIhi stem cells that resist myeloablation and neoplastic expansion
J Li, MJ Williams, HJ Park, HP Bastos, X Wang, D Prins, NK Wilson, ...Blood, The Journal of the American Society of Hematology 140 (14), 1592-1606, 2022202
8
2022
SETBP1 overexpression acts in the place of class-defining mutations to drive FLT3-ITD–mutant AML
S Pacharne, OM Dovey, JL Cooper, M Gu, MJ Friedrich, SS Rajan, ...Blood advances 5 (9), 2412-2425, 2021202
8
2021
Clonal hematopoiesis is not significantly associated with Covid-19 disease severity
Y Zhou, R Shalhoub, SN Rogers, S Yu, M Gu, MA Fabre, PM Quiros, ...Blood, The Journal of the American Society of Hematology 140 (14), 160-16, 2022202
5
2022
Computational analysis of peripheral blood smears detects disease-associated cytomorphologies
JG de Almeida, E Gudgin, M Besser, WG Dunn, J Cooper, T Haferlach, ...medRxiv, 2022.04. 19.2227757, 2022202
3
2022
The CADM1 tumor suppressor gene is a major candidate gene in MDS with deletion of the long arm of chromosome 11
M Lafage-Pochitaloff, B Gerby, V Baccini, L Largeaud, V Fregona, ...Blood Advances 6 (2), 86-98, 2022202
3
2022
Npm1 haploinsufficiency in collaboration with MEIS1 is sufficient to induce AML in mice
A Muranyi, T Ammer, A Kechter, VPS Rawat, A Sinha, ...Blood Advances 7 (3), 351-364, 030
2
2023

Referred From: https://scholar.google.co.uk/citations?user=Zk0-VNQAAAAJ&hl=en

Cited by
Citations 16298
h-index 54
i10-index 102
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