Author

Derin B Keskin

Dana Farber Cancer Institute - Cited by 11,430 - Immuno-oncology

Biography

Derin B Keskin  is a well-known researcher working in Department of Internal Medicine, University Hospital Merkur and has extended valuable service for many years and has been a recipient of many awards and grants.
Title
Cited by
Year
Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma
Z Hu, DE Leet, RL Allesøe, G Oliveira, S Li, AM Luoma, J Liu, J Forman, ...Nature medicine 27 (3), 515-525, 2021202
220
2021
Phenotype, specificity and avidity of antitumour CD8+ T cells in melanoma
G Oliveira, K Stromhaug, S Klaeger, T Kula, DT Frederick, PM Le, ...Nature 596 (7870), 119-125, 2021202
190
2021
Progressive immune dysfunction with advancing disease stage in renal cell carcinoma
DA Braun, K Street, KP Burke, DL Cookmeyer, T Denize, CB Pedersen, ...Cancer Cell 39 (5), 632-648. e8, 2021202
178
2021
Applying high-dimensional single-cell technologies to the analysis of cancer immunotherapy
SH Gohil, JB Iorgulescu, DA Braun, DB Keskin, KJ LivakNature Reviews Clinical Oncology 18 (4), 244-256, 2021202
116
2021
Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer
T Ouspenskaia, T Law, KR Clauser, S Klaeger, S Sarkizova, F Aguet, B Li, ...Nature biotechnology 40 (2), 209-217, 2022202
86
2022
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs
S Weingarten-Gabbay, S Klaeger, S Sarkizova, LR Pearlman, DY Chen, ...Cell 184 (15), 3962-3980. e17, 2021202
76
2021
Landscape of helper and regulatory antitumour CD4+ T cells in melanoma
G Oliveira, K Stromhaug, N Cieri, JB Iorgulescu, S Klaeger, JO Wolff, ...Nature 605 (7910), 532-538, 2022202
43
2022
Optimized liquid and gas phase fractionation increases HLA-peptidome coverage for primary cell and tissue samples
S Klaeger, A Apffel, KR Clauser, S Sarkizova, G Oliveira, S Rachimi, ...Molecular & Cellular Proteomics 20, 2021202
24
2021
TANTIGEN 2.0: a knowledge base of tumor T cell antigens and epitopes
G Zhang, L Chitkushev, LR Olsen, DB Keskin, V BrusicBMC bioinformatics 22, 1-8, 2021202
24
2021
SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs
S Weingarten-Gabbay, S Klaeger, S Sarkizova, LR Pearlman, DY Chen, ...bioRxiv, 2020.10. 02.324145, 2020202
21
2020
Mapping the evolution of T cell states during response and resistance to adoptive cellular therapy
P Bachireddy, E Azizi, C Burdziak, VN Nguyen, CS Ennis, K Maurer, ...Cell reports 37 (6), 212
20
2021
Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect
P Bachireddy, C Ennis, VN Nguyen, SH Gohil, K Clement, SA Shukla, ...Science translational medicine 12 (561), eabb7661, 2020202
13
2020
Single-cell mRNA Profiles in PBMC
L Yang, Y Zhang, N Mitic, DB Keskin, GL Zhang, L Chitkushev, V Brusic2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM …, 2020202
12
2020
Artificial neural network system for cell classification using single cell RNA expression
X Lin, J Zhong, M Lyu, S Lin, DB Keskin, G Zhang, V Brusic, ...2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM …, 2020202
9
2020
Robust anti‐tumor T cell response with efficient Intratumoral infiltration by nanodisc cancer immunotherapy
R Kuai, PB Singh, X Sun, C Xu, A Hassani Najafabadi, L Scheetz, W Yuan, ...Advanced Therapeutics 3 (), 200004, 2020202
9
2020
Optimizing CpG spatial distribution with DNA origami for Th1-polarized therapeutic vaccination
YC Zeng, OJ Young, CM Wintersinger, FM Anastassacos, JI MacDonald, ...BioRxiv, 2022.06. 0.495340, 2022202
8
2022
Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma
PC Lee, S Klaeger, PM Le, K Korthauer, J Cheng, ...The Journal of clinical investigation 132 (13), 2022202
8
2022
Classification of PBMC cell types using scRNAseq, ANN, and incremental learning
J Zhong, RA Shaikh, WU Haoguo, LIN Xin, CAO Zhiwei, LT Chitkushev, ...2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM …, 2020202
6
2020
Classification of single cell types during leukemia therapy using artificial neural networks
LYU Minjie, M Radenkovic, DB Keskin, V Brusic2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM …, 2020202
6
2020
Improved T-cell immunity following neoadjuvant chemotherapy in ovarian cancer
M Liu, N Tayob, L Penter, ML Sellars, A Tarren, V Chea, I Carulli, T Huang, ...Clinical Cancer Research 28 (1), 336-3366, 2022202
5
2022