Author

Ann-Hwee Lee

Regeneron Pharmaceuticals - Cited by 22,195

Biography

Ann-Hwee Lee is a well-known researcher working in the Department of Regeneron Pharmaceuticals and has extended valuable service for many years and has been a recipient of many awards and grants.  
Title
Cited by
Year
ER stress sensor XBP1 controls anti-tumor immunity by disrupting dendritic cell homeostasis
JR Cubillos-Ruiz, PC Silberman, MR Rutkowski, S Chopra, ...Cell 161 (7), 1527-1538, 2015201
660
2015
The transcription factor XBP1 is selectively required for eosinophil differentiation
SE Bettigole, R Lis, S Adoro, AH Lee, LA Spencer, PF Weller, ...Nature immunology 16 (8), 829-837, 2015201
190
2015
IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation
S Sun, G Shi, H Sha, Y Ji, X Han, X Shu, H Ma, T Inoue, B Gao, H Kim, ...Nature cell biology 17 (12), 1546-1555, 2015201
164
2015
Pseudotime ordering of single human β-cells reveals states of insulin production and unfolded protein response
Y Xin, G Dominguez Gutierrez, H Okamoto, J Kim, AH Lee, C Adler, M Ni, ...Diabetes 67 (9), 1783-1794, 2018201
151
2018
Transcriptional activation of Fsp27 by the liver‐enriched transcription factor CREBH promotes lipid droplet growth and hepatic steatosis
X Xu, JG Park, JS So, AH LeeHepatology 61 (3), 857-869, 2015201
96
2015
CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis
JG Park, X Xu, S Cho, KY Hur, MS Lee, S Kersten, AH LeeScientific reports 6 (1), 27938, 2016201
68
2016
Association of physicians’ self-compassion with work engagement, exhaustion, and professional life satisfaction
O Babenko, AD Mosewich, A Lee, S KoppulaMedical Sciences 7 (2), 29, 2019201
61
2019
Sec63 and Xbp1 regulate IRE1α activity and polycystic disease severity
SV Fedeles, JS So, A Shrikhande, SH Lee, AR Gallagher, CE Barkauskas, ...The Journal of clinical investigation 125 (5), 1955-1967, 2015201
46
2015
Essential role of X-box binding protein-1 during endoplasmic reticulum stress in podocytes
H Hassan, X Tian, K Inoue, N Chai, C Liu, K Soda, G Moeckel, A Tufro, ...Journal of the American Society of Nephrology: JASN 27 (4), 1055, 2016201
37
2016
XBP1-KLF9 axis acts as a molecular rheostat to control the transition from adaptive to cytotoxic unfolded protein response
EE Fink, S Moparthy, A Bagati, A Bianchi-Smiraglia, BC Lipchick, ...Cell reports 25 (1), 212-223. e4, 2018201
37
2018
MIST1 links secretion and stress as both target and regulator of the unfolded protein response
DA Hess, KM Strelau, A Karki, M Jiang, AC Azevedo-Pouly, AH Lee, ...Molecular and cellular biology 36 (23), 2931-2944, 2016201
33
2016
IRE1α-dependent decay of CReP/Ppp1r15b mRNA increases eukaryotic initiation factor 2α phosphorylation and suppresses protein synthesis
JS So, S Cho, SH Min, SR Kimball, AH LeeMolecular and cellular biology 35 (16), 2761-2770, 2015201
31
2015
Preemptive A ctivation of the I ntegrated S tress R esponse P rotects M ice F rom D iet‐I nduced O besity and I nsulin R esistance by F ibroblast G rowth F actor 21 I nduction
X Xu, C Krumm, JS So, CJ Bare, C Holman, J Gromada, DE Cohen, ...Hepatology 68 (6), 2167-2181, 2018201
30
2018
The differential expression of cide family members is associated with nafld progression from steatosis to steatohepatitis
A Sans, S Bonnafous, D Rousseau, S Patouraux, CM Canivet, PS Leclere, ...Scientific reports 9 (1), 7501, 2019201
25
2019
XBP-1 and the unfolded protein response (UPR)
LH Glimcher, AH Lee, NN IwakoshiNature immunology 21 (9), 963-965, 2020202
24
2020
Loss of Transcription Factor CREBH Accelerates Diet-Induced Atherosclerosis in Ldlr−/− Mice
JG Park, X Xu, S Cho, AH LeeArteriosclerosis, thrombosis, and vascular biology 36 (9), 1772-1781, 2016201
23
2016
Gene Signature of the Human Pancreatic ε Cell
G Dominguez Gutierrez, J Kim, AH Lee, J Tong, JJ Niu, SM Gray, Y Wei, ...Endocrinology 159 (12), 4023-4032, 181
20
2018
Spliced XBP1 rescues renal interstitial inflammation due to loss of Sec63 in collecting ducts
Y Ishikawa, S Fedeles, A Marlier, C Zhang, AR Gallagher, AH Lee, ...Journal of the American Society of Nephrology: JASN 30 (3), 443, 202
19
2019
Critical role of XBP1 in cancer signalling is regulated by PIN1
U Chae, SJ Park, B Kim, S Wei, JS Min, JH Lee, SH Park, AH Lee, KP Lu, ...Biochemical Journal 473 (17), 2603-2610, 2016201
18
2016
Very low density lipoprotein assembly is required for cAMP-responsive element-binding protein H processing and hepatic apolipoprotein A-IV expression
D Cheng, X Xu, T Simon, E Boudyguina, Z Deng, M VerHague, AH Lee, ...Journal of Biological Chemistry 291 (45), 23793-23803, 2016201
18
2016

Referred From: https://scholar.google.com/citations?user=oJDx7pwAAAAJ&hl=en

Cited by
Citations 22195
h-index 46
i10-index 78
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