Author

Alexandru Almasan

Cleveland Clinic & Case Western Reserve University - Cited by 21,972 - cancer - apoptosis - Bcl-2 - autophagy - DNA repair

Biography

Alexandra Almasan is a well-known researcher working in the Department of Molecular Medicine, School of Medicine and has extended valuable service for many years and has been a recipient of many award and grants.  
Title
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy
DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ...Autophagy 12 (1), 1-222, 20169822201
9822
2016
MCL-1 and BCL-xL-dependent resistance to the BCL-2 inhibitor ABT-199 can be overcome by preventing PI3K/AKT/mTOR activation in lymphoid malignancies
GS Choudhary, S Al-Harbi, S Mazumder, BT Hill, MR Smith, J Bodo, ...Cell death & disease 6 (1), e1593-e1593, 2015201
344
2015
Caspase-3 activation is a critical determinant of genotoxic stress-induced apoptosis
GS Choudhary, S Al-Harbi, A AlmasanApoptosis and Cancer: Methods and Protocols, 1-9, 2015201
260
2015
Targeting BCL-2 in B-cell malignancies and overcoming therapeutic resistance
I Kapoor, J Bodo, BT Hill, ED Hsi, A AlmasanCell death & disease 11 (11), 941, 2020202
117
2020
Autophagy inhibition elicits emergence from metastatic dormancy by inducing and stabilizing Pfkfb3 expression
A La Belle Flynn, BC Calhoun, A Sharma, JC Chang, A Almasan, ...Nature communications 10 (1), 3668, 2019201
104
2019
Autophagic flux determines cell death and survival in response to Apo2L/TRAIL (dulanermin)
K Singh, A Sharma, MC Mir, JA Drazba, WD Heston, C Magi-Galluzzi, ...Molecular cancer 13 (1), 1-11, 2014201
68
2014
Cyclin E/Cdk2-dependent phosphorylation of Mcl-1 determines its stability and cellular sensitivity to BH3 mimetics
GS Choudhary, TT Tat, S Misra, BT Hill, MR Smith, A Almasan, ...Oncotarget 6 (19), 16912, 2015201
64
2015
Combination simvastatin and metformin induces G1-phase cell cycle arrest and Ripk1-and Ripk3-dependent necrosis in C4-2B osseous metastatic castration-resistant prostate cancer …
MA Babcook, RM Sramkoski, H Fujioka, F Daneshgari, A Almasan, ...Cell death & disease 5 (11), e1536-e1536, 2014201
58
2014
USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination
A Sharma, T Alswillah, K Singh, P Chatterjee, B Willard, M Venere, ...Autophagy 14 (11), 1976-1990, 2018201
53
2018
Development of novel anti-Cd20 monoclonal antibodies and modulation in Cd20 levels on cell surface: looking to improve immunotherapy response
V Singh, D Gupta, A AlmasanJournal of cancer science & therapy 7 (11), 347, 2015201
52
2015
Resistance to BTK inhibition by ibrutinib can be overcome by preventing FOXO3a nuclear export and PI3K/AKT activation in B-cell lymphoid malignancies
I Kapoor, Y Li, A Sharma, H Zhu, J Bodo, W Xu, ED Hsi, BT Hill, ...Cell death & disease 10 (12), 924, 2019201
52
2019
miR-377-dependent BCL-xL regulation drives chemotherapeutic resistance in B-cell lymphoid malignancies
S Al-Harbi, GS Choudhary, JS Ebron, BT Hill, N Vivekanathan, AH Ting, ...Molecular cancer 14, 1-17, 2015201
48
2015
The TMPRSS2–ERG gene fusion blocks XRCC4-mediated nonhomologous end-joining repair and radiosensitizes prostate cancer cells to PARP inhibition
P Chatterjee, GS Choudhary, T Alswillah, X Xiong, WD Heston, ...Molecular cancer therapeutics 14 (8), 1896-1906, 2015201
46
2015
Targeting mTORC1–mediated metabolic addiction overcomes fludarabine resistance in malignant B cells
A Sharma, AJ Janocha, BT Hill, MR Smith, SC Erzurum, A AlmasanMolecular Cancer Research 12 (9), 1205-1215, 2014201
36
2014
Inhibiting DNA-PK induces glioma stem cell differentiation and sensitizes glioblastoma to radiation in mice
X Fang, Z Huang, K Zhai, Q Huang, W Tao, L Kim, Q Wu, A Almasan, ...Science Translational Medicine 13 (600), eabc75, 2021202
27
2021
USP14 is a deubiquitinase for Ku70 and critical determinant of non-homologous end joining repair in autophagy and PTEN-deficient cells
A Sharma, T Alswillah, I Kapoor, P Debjani, B Willard, MK Summers, ...Nucleic acids research 48 (2), 736-747, 2020202
26
2020
Development of venetoclax for therapy of lymphoid malignancies
H Zhu, A AlmasanDrug design, development and therapy, 685-694, 2017201
26
2017
Nudix hydrolase NUDT16 regulates 53BP1 protein by reversing 53BP1 ADP-ribosylation
F Zhang, L Lou, B Peng, X Song, O Reizes, A Almasan, Z GongCancer research 80 (5), 999-1010, 2022202
24
2022
Surface levels of CD20 determine anti-CD20 antibodies mediated cell death in vitro
V Singh, D Gupta, R Arora, RP Tripathi, A Almasan, RM MacklisPloS one 9 (11), e111113, 2014201
23
2014
Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (vol 12, pg 1, 2015)
D KliosnkyAutophagy 12 (2), 443-443, 2016201
22
2016

Referred From: https://scholar.google.com/citations?user=T25Wih4AAAAJ&hl=en

Cited by
Citations 21972
h-index 53
i10-index 99
Recommended Journals
Open Access Journals