Author

Philip J Gregory

Associate Professor, Centre for Cancer Biology, University of South Australia - Cited by 12,375 - microRNAs - gene expression - cancer metastasis - EMT - alternative splicing

Biography

Associate Professor Philip Gregory Head, Gene Regulation in Cancer Laboratory Centre for Cancer Biology: An Alliance between the University of South Australia and SA Pathology. Research scientist interested in the complexity of the transcriptome, the mechanisms regulating it, and how it influences cell transitions involved in cancer progression.
Title
Cited by
Year
The RNA binding protein quaking regulates formation of circRNAs
SJ Conn, KA Pillman, J Toubia, VM Conn, M Salmanidis, CA Phillips, ...Cell 160 (6), 1125-1134, 2015201
2015
A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition
CP Bracken, PA Gregory, N Kolesnikoff, AG Bert, J Wang, MF Shannon, ...Cancer research 68 (19), 7846-7854, 2008200
2008
An autocrine TGF-β/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
PA Gregory, CP Bracken, E Smith, AG Bert, JA Wright, S Roslan, M Morris, ...Molecular biology of the cell 22 (10), 1686-1698, 2011201
640
2011
MicroRNAs as regulators of epithelial-mesenchymal transition
PA Gregory, CP Bracken, AG Bert, GJ GoodallCell cycle 7 (20), 3112-3117, 2008200
604
2008
Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression
DL Gibbons, W Lin, CJ Creighton, ZH Rizvi, PA Gregory, GJ Goodall, ...Genes & development 23 (18), 2140-2151, 2009200
539
2009
The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200–dependent pathway in mice
Y Yang, YH Ahn, DL Gibbons, Y Zang, W Lin, N Thilaganathan, ...The Journal of clinical investigation 121 (4), 1373-1385, 2011201
223
2011
Epigenetic modulation of the miR-200 family is associated with transition to a breast cancer stem-cell-like state
YY Lim, JA Wright, JL Attema, PA Gregory, AG Bert, E Smith, D Thomas, ...Journal of cell science 126 (10), 2256-2266, 2013201
220
2013
ZEB1 drives prometastatic actin cytoskeletal remodeling by downregulating miR-34a expression
YH Ahn, DL Gibbons, D Chakravarti, CJ Creighton, ZH Rizvi, HP Adams, ...The Journal of clinical investigation 122 (9), 3170-3183, 2012201
179
2012
Mutant p53 drives invasion in breast tumors through up-regulation of miR-155
PM Neilsen, JE Noll, S Mattiske, CP Bracken, PA Gregory, RB Schulz, ...Oncogene 32 (24), 2992-3000, 2013201
173
2013
MiRNA-205 modulates cellular invasion and migration via regulating zinc finger E-box binding homeobox 2 expression in esophageal squamous cell carcinoma cells
K Matsushima, H Isomoto, N Yamaguchi, N Inoue, H Machida, ...Journal of translational medicine 9, 1-12, 2011201
167
2011
The role of microRNAs in metastasis and epithelial-mesenchymal transition
CP Bracken, PA Gregory, Y Khew-Goodall, GJ GoodallCellular and Molecular Life Sciences 66, 1682-1699, 2009200
158
2009
Genome‐wide identification of miR‐200 targets reveals a regulatory network controlling cell invasion
CP Bracken, X Li, JA Wright, DM Lawrence, KA Pillman, M Salmanidis, ...The EMBO journal 33 (18), 2040-2056, 2014201
143
2014
Mechanisms of vitamin D3 metabolite repression of IgE-dependent mast cell activation
KH Yip, N Kolesnikoff, C Yu, N Hauschild, H Taing, L Biggs, D Goltzman, ...Journal of Allergy and Clinical Immunology 133 (5), 1356-4. e14, 2014201
136
2014
MiR-200 can repress breast cancer metastasis through ZEB1-independent but moesin-dependent pathways
X Li, S Roslan, CN Johnstone, JA Wright, CP Bracken, M Anderson, ...Oncogene 33 (31), 4077-4088, 2014201
129
2014
MicroRNA-194 promotes prostate cancer metastasis by inhibiting SOCS2
R Das, PA Gregory, RC Fernandes, I Denis, Q Wang, SL Townley, ...Cancer research 77 (4), 1021-1034, 2017201
107
2017
A ZEB1-miR-375-YAP1 pathway regulates epithelial plasticity in prostate cancer
LA Selth, R Das, SL Townley, I Coutinho, AR Hanson, MM Centenera, ...Oncogene 36 (1), 24-34, 2017201
104
2017
The microRNA-200 family regulates epithelial to mesenchymal transition
EL Paterson, N Kolesnikoff, PA Gregory, AG Bert, Y Khew-Goodall, ...The Scientific World Journal 8, 901-904, 2008200
95
2008
Combinatorial targeting by microRNAs co-ordinates post-transcriptional control of EMT
J Cursons, KA Pillman, KG Scheer, PA Gregory, M Foroutan, ...Cell systems 7 (1), 77-91. e7, 2018201
88
2018
miR‐200/375 control epithelial plasticity‐associated alternative splicing by repressing the RNA‐binding protein Quaking
KA Pillman, CA Phillips, S Roslan, J Toubia, BK Dredge, AG Bert, R Lumb, ...The EMBO journal 37 (13), e99016, 2018201
74
2018