Author

Marcy Hernick

Appalachian College of Pharmacy - Cited by 982

Biography

Dr. Marcy Hernick serves the College an Associate Professor in the Pharmaceutical Sciences Department. Dr. Hernick was raised in upstate New York and received her B.S. in Pharmacy from Albany College of Pharmacy in 1998. She attended graduate school at Purdue University in the Department of Medicinal Chemistry and Molecular Pharmacology working in the laboratory of Dr. Richard Borch. Here her research was focused on the development of phosphoramidate prodrugs as anticancer agents. After finishing her Ph.D. in 2002, 
Title
Cited by
Year
Zinc hydrolases: the mechanisms of zinc-dependent deacetylases
M Hernick, CA FierkeArchives of biochemistry and biophysics 433 (1), 71-84, 2005200
219
2005
The Arabidopsis thaliana Myo-Inositol 1-Phosphate Synthase1 Gene Is Required for Myo-inositol Synthesis and Suppression of Cell Death
JL Donahue, SR Alford, J Torabinejad, RE Kerwin, A Nourbakhsh, ...The Plant Cell 22 (3), 888-903, 2010201
205
2010
UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase functions through a general acid-base catalyst pair mechanism
M Hernick, HA Gennadios, DA Whittington, KM Rusche, DW Christianson, ...Journal of Biological Chemistry 280 (17), 16969-16978, 2005200
66
2005
Design, synthesis, and biological evaluation of indolequinone phosphoramidate prodrugs targeted to DT-diaphorase
M Hernick, C Flader, RF BorchJournal of medicinal chemistry 45 (16), 3540-3548, 2002200
62
2002
Active site metal ion in UDP-3-O-((R)-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) switches between Fe (II) and Zn (II) depending on cellular conditions
SG Gattis, M Hernick, CA FierkeJournal of Biological Chemistry 285 (), 33788-33796, 2010201
44
2010
Activation of Escherichia coli UDP-3-O-[(R)-3-hydroxymyristoyl]-N-acetylglucosamine Deacetylase by Fe2+ Yields a More Efficient Enzyme with Altered Ligand …
M Hernick, SG Gattis, JE Penner-Hahn, CA FierkeBiochemistry 49 (10), 2246-2255, 2010201
40
2010
Mycothiol: a target for potentiation of rifampin and other antibiotics against Mycobacterium tuberculosis
M HernickExpert review of anti-infective therapy 11 (1), 49-67, 2013201
31
2013
Catalytic Mechanism and Molecular Recognition of E. coli UDP-3-O-(R-3-Hydroxymyristoyl)-N-acetylglucosamine Deacetylase Probed by Mutagenesis
M Hernick, CA FierkeBiochemistry 45 (51), 15240-15248, 2006200
31
2006
Catalytic mechanism and molecular recognition of E. coli UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase probed by mutagenesis
M Hernick, CA FierkeBiochemistry 45 (51), 15240-15248, 2006200
31
2006
The activity and cofactor preferences of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside deacetylase (MshB) change depending on environmental conditions
X Huang, E Kocabas, M HernickJournal of Biological Chemistry 286 (23), 20275-20282, 2011201
29
2011
Studies on the mechanisms of activation of indolequinone phosphoramidate prodrugs
M Hernick, RF BorchJournal of medicinal chemistry 46 (1), 148-154, 2003200
27
2003
Residue Ionization in LpxC Directly Observed by 67Zn NMR Spectroscopy
AS Lipton, RW Heck, M Hernick, CA Fierke, PD EllisJournal of the American Chemical Society 130 (38), 171-179, 2008200
26
2008
Test-enhanced learning in an immunology and infectious disease medicinal chemistry/pharmacology course
M HernickAmerican Journal of Pharmaceutical Education 79 (7), 2015201
26
2015
Mechanisms of metal-dependent hydrolases in metabolism
M Hernick, C FierkeComprehensive Natural Products II Chemistry and Biology. Netherlands …, 2010201
23
2010
A fluorescence-based assay for measuring N-acetyl-1-d-myo-inosityl-2-amino-2-deoxy-α-d-glucopyranoside deacetylase activity
X Huang, M HernickAnalytical biochemistry 414 (2), 278-281, 2011201
22
2011
Examination of mechanism of N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-α-D-glucopyranoside deacetylase (MshB) reveals unexpected role for dynamic tyrosine
X Huang, M HernickJournal of Biological Chemistry 287 (13), 10424-10434, 2012201
18
2012
Structure and function of the LmbE-like superfamily
S Viars, J Valentine, M HernickBiomolecules 4 (2), 527-545, 2014201
13
2014
Improving student understanding of lipids concepts in a biochemistry course using test-enhanced learning
S Horn, M HernickChemistry Education Research and Practice 16 (4), 918-928, 2015201
13
2015
Phosphoramide compounds
RF Borch, M Hernick, C FladerUS Patent 6,656,926, 2003200
10
2003
Phosphoramide compounds
RF Borch, M Hernick, C FladerUS Patent 7,304,046, 2007200
8
2007

Referred From: https://scholar.google.com/citations?user=PgSnJlkAAAAJ&hl=en

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Citations 982
h-index 15
i10-index 18
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