Author

Sardar Sindhu

Scientist in Immunology, Dasman Diabetes Institute - Cited by 2,301 - Cellular & Molecular Immunology - Innate Immunity - Metabolic inflammation - Obesity/Type-2 diabetes

Biography

 Sardar Sindhu currently works at Immunology and Innovative Cell Therapy Unit from the Dasman Diabetes Institute (DDI), Kuwait. urpose: Changes in plasma levels of T-cell cytokines may result in inflammatory disorders, including metabolic disease. The changes in circulatory IL-5 levels in obesity and type-2 diabetes (T2D) and their relationship with major Th1 and Th2 cytokines are poorly understood.   
Title
Cited by
Year
Robust antibody levels in both diabetic and non-diabetic individuals after BNT162b2 mRNA COVID-19 vaccination
H Ali, A Alterki, S Sindhu, B Alahmad, M Hammad, S Al-Sabah, ...Frontiers in immunology 12, 752233, 2021202
69
2021
Previous COVID-19 infection and antibody levels after vaccination
H Ali, B Alahmad, AA Al-Shammari, A Alterki, M Hammad, P Cherian, ...Frontiers in public health 9, 778243, 2021202
61
2021
Elevated adipose tissue associated IL-2 expression in obesity correlates with metabolic inflammation and insulin resistance
S Kochumon, A Al Madhoun, F Al-Rashed, R Thomas, S Sindhu, ...Scientific reports 10 (1), 16364, 2020202
40
2020
Repetitive intermittent hyperglycemia drives the M1 polarization and inflammatory responses in THP-1 macrophages through the mechanism involving the TLR4-IRF5 pathway
F Al-Rashed, S Sindhu, H Arefanian, A Al Madhoun, S Kochumon, ...Cells 9 (8), 1892, 2020202
33
2020
ROS/TNF-α Crosstalk Triggers the Expression of IL-8 and MCP-1 in Human Monocytic THP-1 Cells via the NF-κB and ERK1/2 Mediated Signaling
N Akhter, A Wilson, R Thomas, F Al-Rashed, S Kochumon, A Al-Roub, ...International journal of molecular sciences 22 (19), 10519, 2021202
23
2021
Dental pulp stem cells derived from adult human third molar tooth: a brief review
A Al Madhoun, S Sindhu, D Haddad, M Atari, R Ahmad, F Al-MullaFrontiers in Cell and Developmental Biology 9, 717624, 2021202
23
2021
Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells
F Al-Rashed, Z Ahmad, AJ Snider, R Thomas, S Kochumon, M Melhem, ...Scientific Reports 11 (1), 8259, 212
20
2021
Neutral sphingomyelinase‐2 and cardiometabolic diseases
S Sindhu, YH Leung, H Arefanian, SRM Madiraju, F Al‐Mulla, R Ahmad, ...Obesity Reviews 22 (8), e13248, 2021202
15
2021
Short sleep duration and its association with obesity and other metabolic risk factors in Kuwaiti urban adults
F Al-Rashed, S Sindhu, A Al Madhoun, A Alghaith, R Azim, F Al-Mulla, ...Nature and science of sleep, 1225-1241, 2021202
15
2021
Stearic acid and tnf-α co-operatively potentiate mip-1α production in monocytic cells via myd88 independent tlr4/tbk/irf3 signaling pathway
S Kochumon, H Arefanian, R Azim, S Shenouda, T Jacob, N Abu Khalaf, ...Biomedicines 8 (10), 403, 2020202
15
2020
Short chain fatty acid acetate increases tnfα-induced mcp-1 production in monocytic cells via acsl1/mapk/nf-κb axis
A Al-Roub, N Akhter, A Al-Sayyar, A Wilson, R Thomas, S Kochumon, ...International Journal of Molecular Sciences 22 (14), 7683, 2021202
11
2021
Comparative proteomic analysis identifies EphA2 as a specific cell surface marker for Wharton’s jelly-derived mesenchymal stem cells
A Al Madhoun, SK Marafie, D Haddad, M Melhem, M Abu-Farha, H Ali, ...International journal of molecular sciences 21 (17), 6437, 2020202
11
2020
IL-1β and TNFα cooperativity in regulating IL-6 expression in adipocytes depends on CREB binding and H3K14 acetylation
A Al-Roub, A Al Madhoun, N Akhter, R Thomas, L Miranda, T Jacob, ...Cells 10 (11), 3228, 2021202
9
2021
Elevated resting heart rate as a predictor of inflammation and cardiovascular risk in healthy obese individuals
F Al-Rashed, S Sindhu, A Al Madhoun, Z Ahmad, D AlMekhled, R Azim, ...Scientific Reports 11 (1), 13883, 2021202
9
2021
Adipose tissue steroid receptor rna activator 1 (sra1) expression is associated with obesity, insulin resistance, and inflammation
S Kochumon, H Arefanian, S Sindhu, S Shenouda, R Thomas, F Al-Mulla, ...Cells 10 (10), 2602, 2021202
7
2021
Dectin-1 as a potential inflammatory biomarker for metabolic inflammation in adipose tissue of individuals with obesity
A Al Madhoun, S Kochumon, F Al-Rashed, S Sindhu, R Thomas, ...Cells 11 (18), 2879, 2022202
6
2022
Ifn-γ and lps induce synergistic expression of ccl2 in monocytic cells via h3k27 acetylation
N Akhter, S Kochumon, A Hasan, A Wilson, R Nizam, A Al Madhoun, ...Journal of inflammation research, 4291-4302, 2022202
5
2022
Increased adipose tissue expression of IL-23 associates with inflammatory markers in people with high LDL cholesterol
S Kochumon, A Hasan, F Al-Rashed, S Sindhu, R Thomas, T Jacob, ...Cells 11 (19), 3072, 2022202
5
2022
Tnf-α increases ip-10 expression in mcf-7 breast cancer cells via activation of the jnk/c-jun pathways
S Kochumon, A Al-Sayyar, T Jacob, A Hasan, F Al-Mulla, S Sindhu, ...Biomolecules 11 (9), 1355, 2021202
4
2021
Microarray analysis reveals ONC201 mediated differential mechanisms of CHOP gene regulation in metastatic and nonmetastatic colorectal cancer cells
A Al Madhoun, D Haddad, M Al Tarrah, S Jacob, W Al-Ali, R Nizam, ...Scientific Reports 11 (1), 11893, 2021202
4
2021

Referred From: https://scholar.google.com/citations?user=8Q5QJNsAAAAJ

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Citations 2301
h-index 27
i10-index 44
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