Author

Giuseppina Simone

Dirigente di Ricerca - Istituto di Biostrutture e Bioimmagini-CNR - Cited by 10,634 - Structural Biology

Biography

Giuseppina Simone is from Center for Advanced Biomaterials for Health CareItalian Institute, Italy. Recently he published an article in the Journal of Glycomics and Lipidomics.
Title
Cited by
Year
Carbonic anhydrase inhibitors targeting metabolism and tumor microenvironment
A Angeli, F Carta, A Nocentini, JY Winum, R Zalubovskis, A Akdemir, ...Metabolites 10 (10), 412, 2020202
103
2020
Exploring structural properties of potent human carbonic anhydrase inhibitors bearing a 4-(cycloalkylamino-1-carbonyl) benzenesulfonamide moiety
MR Buemi, A Di Fiore, L De Luca, A Angeli, F Mancuso, S Ferro, SM Monti, ...European journal of medicinal chemistry 163, 443-452, 2019201
36
2019
Human carbonic anhydrases and post-translational modifications: a hidden world possibly affecting protein properties and functions
A Di Fiore, CT Supuran, A Scaloni, G De SimoneJournal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1450-1461, 2020202
19
2020
Biochemical and structural insights into carbonic anhydrase XII/Fab6A10 complex
V Alterio, M Kellner, D Esposito, F Liesche-Starnecker, S Bua, ...Journal of Molecular Biology 431 (24), 4910-4921, 202
19
2019
Biochemical and structural characterisation of a protozoan beta-carbonic anhydrase from Trichomonas vaginalis
LJ Urbański, A Di Fiore, L Azizi, VP Hytönen, M Kuuslahti, M Buonanno, ...Journal of Enzyme Inhibition and Medicinal Chemistry 35 (1), 1292-1299, 2020202
18
2020
Phenyl (thio) phosphon (amid) ate benzenesulfonamides as potent and selective inhibitors of human carbonic anhydrases II and VII counteract allodynia in a mouse model of …
A Nocentini, V Alterio, S Bua, L Micheli, D Esposito, M Buonanno, ...Journal of Medicinal Chemistry 63 (10), 5185-5200, 2020202
16
2020
Weight loss facilitates reduction of left ventricular mass in obese hypertensive patients: The Campania Salute Network
MT Lønnebakken, C Mancusi, MA Losi, E Gerdts, R Izzo, MV Manzi, ...Nutrition, Metabolism and Cardiovascular Diseases 29 (2), 185-190, 2019201
16
2019
Inhibition of carbonic anhydrases IX/XII by SLC-0111 boosts cisplatin effects in hampering head and neck squamous carcinoma cell growth and invasion
A Sarnella, Y Ferrara, L Auletta, S Albanese, L Cerchia, V Alterio, ...Journal of Experimental & Clinical Cancer Research 41 (1), 122, 2022202
14
2022
A novel inhibitor of carbonic anhydrases prevents hypoxia-induced TNBC cell plasticity
A Sarnella, G D’avino, BS Hill, V Alterio, JY Winum, CT Supuran, ...International Journal of Molecular Sciences 21 (21), 8405, 2020202
14
2020
Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase …
E Langella, V Alterio, K D’Ambrosio, R Cadoni, JY Winum, CT Supuran, ...Journal of enzyme inhibition and medicinal chemistry 34 (1), 1498-1505, 2019201
10
2019
Intrinsically disordered features of carbonic anhydrase IX proteoglycan-like domain
E Langella, M Buonanno, G De Simone, SM MontiCellular and Molecular Life Sciences 78, 205-2067, 2021202
9
2021
Looking toward the Rim of the Active Site Cavity of Druggable Human Carbonic Anhydrase Isoforms
F Mancuso, A Di Fiore, L De Luca, A Angeli, SM Monti, G De Simone, ...ACS Medicinal Chemistry Letters 11 (5), 1000-1005, 2020202
8
2020
Inhibition of the newly discovered β‑carbonic anhydrase from the protozoan pathogen Trichomonas vaginalis with inorganic anions and small molecules
LJ Urbański, A Angeli, VP Hytönen, A Di Fiore, S Parkkila, G De Simone, ...Journal of Inorganic Biochemistry 213, 111274, 2020202
8
2020
Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach
G De Simone, A Di Fiore, E Truppo, E Langella, D Vullo, CT Supuran, ...Journal of Enzyme Inhibition and Medicinal Chemistry 34 (1), 1506-1510, 2019201
7
2019
Post-translational modifications in tumor-associated carbonic anhydrases
A Di Fiore, CT Supuran, A Scaloni, G De SimoneAmino Acids 54 (4), 543-558, 2022202
6
2022
The amazing world of IDPs in human diseases
SM Monti, G De Simone, E LangellaBiomolecules 11 (2), 333, 2021202
6
2021
Biochemical, structural, and computational studies of a γ-carbonic anhydrase from the pathogenic bacterium Burkholderia pseudomallei
A Di Fiore, V De Luca, E Langella, A Nocentini, M Buonanno, SM Monti, ...Computational and Structural Biotechnology Journal 20, 418-4194, 2022202
5
2022
Benzyl alcohol inhibits carbonic anhydrases by anchoring to the zinc coordinated water molecule
G De Simone, S Bua, CT Supuran, V AlterioBiochemical and Biophysical Research Communications 48, 217-221, 2021202
5
2021
Zeta-carbonic anhydrases show CS2 hydrolase activity: A new metabolic carbon acquisition pathway in diatoms?
V Alterio, E Langella, M Buonanno, D Esposito, A Nocentini, E Berrino, ...Computational and Structural Biotechnology Journal 19, 3427-3436, 2021202
5
2021
α-CAs from photosynthetic organisms
E Langella, A Di Fiore, V Alterio, SM Monti, G De Simone, K D’AmbrosioInternational Journal of Molecular Sciences 23 (19), 1204, 2022202
5
2022