Author

Garigen S

University of Rochester - Cited by 12,530 - proteostasis - proteomics - protein folding - prions - aging

Biography

Dr. Sarah Garigen is an internist in Rochester, New York. She received her medical degree from Jacobs School of Medicine and Biomedical Sciences and has been in practice for 5 years.
Title
Cited by
Year
A data processing pipeline for mammalian proteome dynamics studies using stable isotope metabolic labeling
S Guan, JC Price, SB Prusiner, S Ghaemmaghami, AL BurlingameMolecular & Cellular Proteomics 10 (12), 2011201
127
2011
Global analysis of cellular protein flux quantifies the selectivity of basal autophagy
T Zhang, S Shen, J Qu, S GhaemmaghamiCell reports 14 (10), 2426-2439, 2016201
80
2016
Time-resolved analysis of proteome dynamics by tandem mass tags and stable isotope labeling in cell culture (TMT-SILAC) hyperplexing
KA Welle, T Zhang, JR Hryhorenko, S Shen, J Qu, S GhaemmaghamiMolecular & Cellular Proteomics 15 (12), 3551-3563, 2016201
76
2016
Global analysis of methionine oxidation provides a census of folding stabilities for the human proteome
EJ Walker, JQ Bettinger, KA Welle, JR Hryhorenko, S GhaemmaghamiProceedings of the National Academy of Sciences 116 (13), 6081-6090, 2019201
66
2019
Conformational transformation and selection of synthetic prion strains
S Ghaemmaghami, JC Watts, HO Nguyen, S Hayashi, SJ DeArmond, ...Journal of molecular biology 413 (3), 7-542, 2011201
52
2011
Intracerebral infusion of antisense oligonucleotides into prion-infected mice
KN Friberg, G Hung, E Wancewicz, K Giles, C Black, S Freier, F Bennett, ...Molecular Therapy-Nucleic Acids 1, 2012201
45
2012
Compartment modeling for mammalian protein turnover studies by stable isotope metabolic labeling
S Guan, JC Price, S Ghaemmaghami, SB Prusiner, AL BurlingameAnalytical chemistry 84 (9), 4014-4021, 2012201
44
2012
Redox-mediated regulation of an evolutionarily conserved cross-β structure formed by the TDP43 low complexity domain
Y Lin, X Zhou, M Kato, D Liu, S Ghaemmaghami, BP Tu, SL McKnightProceedings of the National Academy of Sciences 117 (46), 28727-28734, 2020202
39
2020
Quantitative analysis of in vivo methionine oxidation of the human proteome
JQ Bettinger, KA Welle, JR Hryhorenko, S GhaemmaghamiJournal of proteome research 19 (2), 624-633, 2019201
39
2019
Cross-species comparison of proteome turnover kinetics
K Swovick, KA Welle, JR Hryhorenko, A Seluanov, V Gorbunova, ...Molecular & Cellular Proteomics 17 (4), 580-591, 2018201
39
2018
Convergent replication of mouse synthetic prion strains
S Ghaemmaghami, DW Colby, HOB Nguyen, S Hayashi, A Oehler, ...The American journal of pathology 182 (3), 866-874, 2013201
39
2013
Interspecies differences in proteome turnover kinetics are correlated with life spans and energetic demands
K Swovick, D Firsanov, KA Welle, JR Hryhorenko, JP Wise, C George, ...Molecular & Cellular Proteomics 20, 2021202
38
2021
Developmentally regulated H2Av buffering via dynamic sequestration to lipid droplets in Drosophila embryos
MR Johnson, RA Stephenson, S Ghaemmaghami, MA WelteElife 7, e021, 2018201
36
2018
Proteome-wide modulation of degradation dynamics in response to growth arrest
T Zhang, C Wolfe, A Pierle, KA Welle, JR Hryhorenko, S GhaemmaghamiProceedings of the National Academy of Sciences 114 (48), E10329-E10338, 2017201
27
2017
Successes and Challenges in Phenotype-Based Lead Discovery for Prion Diseases: Miniperspective
S Ghaemmaghami, M Russo, AR RensloJournal of Medicinal Chemistry 57 (16), 6919-6929, 2014201
26
2014
Pharmacokinetics of quinacrine efflux from mouse brain via the P-glycoprotein efflux transporter
M Ahn, S Ghaemmaghami, Y Huang, PW Phuan, BCH May, K Giles, ...PloS one 7 (7), e39112, 2012201
26
2012
Antiprion compounds that reduce PrPSc levels in dividing and stationary-phase cells
BM Silber, JR Gever, Z Li, A Gallardo-Godoy, AR Renslo, K Widjaja, ...Bioorganic & medicinal chemistry 21 (24), 7999-8012, 2013201
23
2013
Kinetics of precursor labeling in stable isotope labeling in cell cultures (SILAC) experiments
T Zhang, JC Price, E Nouri-Nigjeh, J Li, MK Hellerstein, J Qu, ...Analytical chemistry 86 (22), 11334-11341, 2014201
18
2014
Biology and genetics of PrP prion strains
S GhaemmaghamiCold Spring Harbor Perspectives in Medicine 7 (8), a026922, 2017201
18
2017
Increased degradation rates in the components of the mitochondrial oxidative phosphorylation chain in the cerebellum of old mice
A Popa-Wagner, RE Sandu, C Cristin, A Uzoni, KA Welle, JR Hryhorenko, ...Frontiers in Aging Neuroscience 10, 32, 2018201
17
2018