Author

James Melrose

University of Sydney; University of NSW; Kolling Institute - Cited by 8,344 - stem cells - intervertebral disc - extracellular matrix - cartilage - meniscus

Biography

Dr. James Melrose is currently working as a Senior Researcher at Raymond Purves Bone and Joint Research Laboratory, University of Sydney. Author’s significant publications include “The 7D4, 4C3 and 3B3 (-) Chondroitin Sulphation Motifs are expressed at Sites of Cartilage and Bone Morphogenesis during Foetal Human Knee Joint Development”. Author current research interests include Stem Cells, Intervertebral Disc, Extracellular Matrix.
Title
Cited by
Year
Cancer metastasis: the role of the extracellular matrix and the heparan sulfate proteoglycan perlecan
Z Elgundi, M Papanicolaou, G Major, TR Cox, J Melrose, JM Whitelock, ...Frontiers in oncology 9, 1482, 2020202
95
2020
The glucosinolates: a sulphur glucoside family of mustard anti-tumour and antimicrobial phytochemicals of potential therapeutic application
J MelroseBiomedicines 7 (3), 62, 2019201
57
2019
The inter-α-trypsin inhibitor family: Versatile molecules in biology and pathology
MS Lord, J Melrose, AJ Day, JM WhitelockJournal of Histochemistry & Cytochemistry 68 (12), 907-927, 2020202
49
2020
Keratan sulfate (KS)‐proteoglycans and neuronal regulation in health and disease: the importance of KS‐glycodynamics and interactive capability with neuroregulatory ligands
J MelroseJournal of Neurochemistry 149 (2), 170-194, 2019201
40
2019
Perlecan in pericellular mechanosensory cell-matrix communication, extracellular matrix stabilisation and mechanoregulation of load-bearing connective tissues
F Guilak, AJ Hayes, J MelroseInternational journal of molecular sciences 22 (5), 2716, 2021202
33
2021
Perlecan, a modular instructive proteoglycan with diverse functional properties
J MelroseThe International Journal of Biochemistry & Cell Biology 128, 105849, 2020202
29
2020
Aggrecan, the primary weight-bearing cartilage proteoglycan, has context-dependent, cell-directive properties in embryonic development and neurogenesis: aggrecan glycan side …
AJ Hayes, J MelroseBiomolecules 10 (9), 1244, 2020202
28
2020
Catabolism of fibromodulin in developmental rudiment and pathologic articular cartilage demonstrates novel roles for MMP-13 and ADAMTS-4 in C-terminal processing of SLRPs
CC Shu, CR Flannery, CB Little, J MelroseInternational Journal of Molecular Sciences 20 (3), 579, 2019201
25
2019
The noncollagenous proteins of the intervertebral disc
J Melrose, P GhoshBiology Of Invertebral Disc, 189-7, 2019201
23
2019
Efficacy of administered mesenchymal stem cells in the initiation and co‐ordination of repair processes by resident disc cells in an ovine (Ovis aries) large …
CC Shu, A Dart, R Bell, C Dart, E Clarke, MM Smith, CB Little, J MelroseJOR spine 1 (4), e1037, 2018201
22
2018
Type XI collagen–perlecan–HS interactions stabilise the pericellular matrix of annulus fibrosus cells and chondrocytes providing matrix stabilisation and homeostasis
SM Smith, J MelroseJournal of Molecular Histology 50, 285-294, 2019201
21
2019
Glycosaminoglycan and proteoglycan biotherapeutics in articular cartilage protection and repair strategies: novel approaches to visco‐supplementation in orthobiologics
AJ Hayes, J MelroseAdvanced Therapeutics 2 (8), 1900034, 191
20
2019
Neural tissue homeostasis and repair is regulated via CS and DS proteoglycan motifs
AJ Hayes, J MelroseFrontiers in Cell and Developmental Biology 9, 696640, 2021202
18
2021
The importance of the knee joint meniscal fibrocartilages as stabilizing weight bearing structures providing global protection to human knee-joint tissues
J MelroseCells 8 (4), 324, 2019201
17
2019
Perlecan, a multi-functional, cell-instructive, matrix-stabilizing proteoglycan with roles in tissue development has relevance to connective tissue repair and regeneration
AJ Hayes, BL Farrugia, IJ Biose, GJ Bix, J MelroseFrontiers in Cell and Developmental Biology 10, 856261, 2022202
16
2022
The CNS/PNS extracellular matrix provides instructive guidance cues to neural cells and neuroregulatory proteins in neural development and repair
J Melrose, AJ Hayes, G BixInternational Journal of Molecular Sciences 22 (11), 5583, 2021202
16
2021
3D distribution of perlecan within intervertebral disc chondrons suggests novel regulatory roles for this multifunctional modular heparan sulphate proteoglycan
AJ Hayes, J MelroseEuropean Cells and Materials 41, 73-89, 2021202
14
2021
Electro‐Stimulation, a Promising Therapeutic Treatment Modality for Tissue Repair: Emerging Roles of Sulfated Glycosaminoglycans as Electro‐Regulatory Mediators of Intrinsic …
AJ Hayes, J MelroseAdvanced Therapeutics 3 (11), 2000151, 2020202
14
2020
Perlecan in the natural and cell therapy repair of human adult articular cartilage: can modifications in this proteoglycan be a novel therapeutic approach?
J Garcia, HS McCarthy, JH Kuiper, J Melrose, S RobertsBiomolecules 11 (1), 92, 2021202
12
2021
Mucin-like glycopolymer gels in electrosensory tissues generate cues which direct electrolocation in amphibians and neuronal activation in mammals
J MelroseNeural regeneration research 14 (7), 91, 2019201
11
2019

Referred From: https://scholar.google.com/citations?user=fzBb8KEAAAAJ&hl=en

Cited by
Citations 8344
h-index 47
i10-index 135
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