Author

Rashash A

Associate Professor, School of Biomedical Sciences, The University of Queensland - Cited by 4,481 - Ion Channels (ASIC/Nav) - Pharmacology - venom peptide - Structure-Activity - Mechanism of action..

Biography

Rashash A  working in the Department of Scientific Training and Continuous Studies, National Authority for Remote Sensing and Space Sciences, Cairo, Egypt. He has published more than 30 articles, In the field of Geography, Natural Disasters, Earth Science, Climatic conditions,  Natural Hazards  
Title
Cited by
Year
The concise guide to pharmacology 2019/20: Ion channels
SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ...British journal of pharmacology 176, S142-S228, 2019201
318
2019
Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a
IR Chassagnon, CA McCarthy, YKY Chin, SS Pineda, A Keramidas, ...Proceedings of the National Academy of Sciences 114 (14), 3750-3755, 2017201
177
2017
The concise guide to pharmacology 2021/22: Ion channels
SPH Alexander, A Mathie, JA Peters, EL Veale, J Striessnig, E Kelly, ...British Journal of Pharmacology 178, S157-S245, 2021202
162
2021
Production of recombinant disulfide-rich venom peptides for structural and functional analysis via expression in the periplasm of E. coli
JK Klint, S Senff, NJ Saez, R Seshadri, HY Lau, NS Bende, EAB Undheim, ...PloS one 8 (5), e63865, 2013201
160
2013
Mutations in the voltage-gated potassium channel gene KCNH1 cause Temple-Baraitser syndrome and epilepsy
C Simons, LD Rash, J Crawford, L Ma, B Cristofori-Armstrong, D Miller, ...Nature genetics 47 (1), 73-77, 2015201
132
2015
NaV1. 7 as a pain target–from gene to pharmacology
I Vetter, JR Deuis, A Mueller, MR Israel, H Starobova, A Zhang, LD Rash, ...Pharmacology & therapeutics 172, 73-100, 2017201
123
2017
Inhibition of voltage‐gated Na+ currents in sensory neurones by the sea anemone toxin APETx2
MG Blanchard, LD Rash, S KellenbergerBritish journal of pharmacology 165 (7), 2167-2177, 2012201
102
2012
Acid-sensing ion channel (ASIC) structure and function: Insights from spider, snake and sea anemone venoms
B Cristofori-Armstrong, LD RashNeuropharmacology 127, 173-184, 2017201
85
2017
Chemical synthesis, 3D structure, and ASIC binding site of the toxin mambalgin‐2
CI Schroeder, LD Rash, X Vila‐Farrés, KJ Rosengren, M Mobli, GF King, ...Angewandte Chemie International Edition 53 (4), 1017-1020, 2014201
76
2014
Acid-sensing ion channel pharmacology, past, present, and future…
LD RashAdvances in Pharmacology 79, 35-66, 2017201
59
2017
PcTx1 affords neuroprotection in a conscious model of stroke in hypertensive rats via selective inhibition of ASIC1a
CA McCarthy, LD Rash, IR Chassagnon, GF King, RE WiddopNeuropharmacology 99, 650-657, 2015201
59
2015
Understanding the molecular basis of toxin promiscuity: The analgesic sea anemone peptide APETx2 interacts with acid-sensing ion channel 3 and hERG channels via overlapping …
JE Jensen, B Cristofori-Armstrong, R Anangi, KJ Rosengren, CHY Lau, ...Journal of Medicinal Chemistry 57 (21), 9195-9203, 2014201
49
2014
Inhibition of acid‐sensing ion channels by diminazene and APETx2 evoke partial and highly variable antihyperalgesia in a rat model of inflammatory pain
JYP Lee, NJ Saez, B Cristofori‐Armstrong, R Anangi, GF King, MT Smith, ...British Journal of Pharmacology 175 (12), 2204-2218, 2018201
48
2018
Defining the role of post-synaptic α-neurotoxins in paralysis due to snake envenoming in humans
A Silva, B Cristofori-Armstrong, LD Rash, WC Hodgson, GK IsbisterCellular and molecular life sciences 75, 4465-4478, 2018201
40
2018
Molecular dynamics and functional studies define a hot spot of crystal contacts essential for PcTx1 inhibition of acid‐sensing ion channel 1a
NJ Saez, E Deplazes, B Cristofori‐Armstrong, IR Chassagnon, X Lin, ...British journal of pharmacology 172 (20), 4985-4995, 2015201
39
2015
The structure, dynamics and selectivity profile of a NaV1.7 potency-optimised huwentoxin-IV variant
S Rahnama, JR Deuis, FC Cardoso, V Ramanujam, RJ Lewis, LD Rash, ...PLoS one 12 (3), e0173551, 2017201
36
2017
Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3
JE Jensen, M Mobli, A Brust, PF Alewood, GF King, LD RashMarine Drugs 10 (7), 1511-1527, 2012201
34
2012
Modulation of ion channels by cysteine-rich peptides: from sequence to structure
M Mobli, EAB Undheim, LD RashAdvances in Pharmacology 79, 199-223, 2017201
31
2017
Discovery and molecular interaction studies of a highly stable, tarantula peptide modulator of acid-sensing ion channel 1
SY Er, B Cristofori-Armstrong, P Escoubas, LD RashNeuropharmacology 127, 185-195, 2017201
31
2017