Author

Christopher A. Tate

Programme Leader, MRC Laboratory of Molecular Biology, Cambridge - Cited by 18,016 - Membrane proteins

Biography

Christopher A. Tate, Department of Geography, University of Idaho, Moscow.  He  has published more than 30 articles, In the field of Environment, Geospatial Science, Natural Disasters,Earth Sciences, Geographic Information System. 
Title
Cited by
Year
Mini G protein probes for active G protein–coupled receptors (GPCRs) in live cells
Q Wan, N Okashah, A Inoue, R Nehmé, B Carpenter, CG Tate, ...Journal of Biological Chemistry 293 (19), 7466-7473, 2018201
221
2018
Cryo-EM structure of the adenosine A2A receptor coupled to an engineered heterotrimeric G protein
J García-Nafría, Y Lee, X Bai, B Carpenter, CG Tateelife 7, e35946, 2018201
217
2018
PtdIns (4, 5) P2 stabilizes active states of GPCRs and enhances selectivity of G-protein coupling
HY Yen, KK Hoi, I Liko, G Hedger, MR Horrell, W Song, D Wu, P Heine, ...Nature 559 (7714), 423-427, 2018201
216
2018
Impact of GPCR structures on drug discovery
M Congreve, C de Graaf, NA Swain, CG TateCell 181 (1), 81-91, 2020202
205
2020
Cryo-EM structure of the serotonin 5-HT1B receptor coupled to heterotrimeric Go
J García-Nafría, R Nehmé, PC Edwards, CG TateNature 558 (7711), 620-623, 2018201
197
2018
Molecular basis of β-arrestin coupling to formoterol-bound β1-adrenoceptor
Y Lee, T Warne, R Nehmé, S Pandey, H Dwivedi-Agnihotri, M Chaturvedi, ...Nature 583 (7818), 862-866, 2020202
152
2020
Cryo-EM structures of GPCRs coupled to Gs, Gi and Go
J García-Nafría, CG TateMolecular and cellular endocrinology 488, 1-13, 2019201
115
2019
Cryo-electron microscopy: moving beyond X-ray crystal structures for drug receptors and drug development
J García-Nafría, CG TateAnnual review of pharmacology and toxicology 60, 51-71, 2020202
99
2020
Insight into partial agonism by observing multiple equilibria for ligand-bound and Gs-mimetic nanobody-bound β1-adrenergic receptor
AS Solt, MJ Bostock, B Shrestha, P Kumar, T Warne, CG Tate, ...Nature communications 8 (1), 1795, 2017201
96
2017
Molecular basis for high-affinity agonist binding in GPCRs
T Warne, PC Edwards, AS Doré, AGW Leslie, CG TateScience 364 (6442), 775-778, 2019201
90
2019
Active state structures of G protein-coupled receptors highlight the similarities and differences in the G protein and arrestin coupling interfaces
B Carpenter, CG TateCurrent opinion in structural biology 45, 124-132, 2017201
74
2017
Crystal structure of rhodopsin in complex with a mini-Go sheds light on the principles of G protein selectivity
CJ Tsai, F Pamula, R Nehmé, J Mühle, T Weinert, T Flock, P Nogly, ...Science advances 4 (9), eaat7052, 2018201
66
2018
Structure of the class D GPCR Ste2 dimer coupled to two G proteins
V Velazhahan, N Ma, G Pándy-Szekeres, AJ Kooistra, Y Lee, DE Gloriam, ...Nature 589 (7840), 148-153, 2021202
60
2021
The molecular control of calcitonin receptor signaling
E Dal Maso, A Glukhova, Y Zhu, J Garcia-Nafria, CG Tate, S Atanasio, ...ACS Pharmacology & Translational Science 2 (1), 31-51, 2019201
40
2019
Structure determination of GPCRs: cryo-EM compared with X-ray crystallography
J García-Nafría, CG TateBiochemical Society Transactions 49 (5), 2345-2355, 2021202
38
2021
How do branched detergents stabilize GPCRs in micelles?
S Lee, S Ghosh, S Jana, N Robertson, CG Tate, N VaidehiBiochemistry 59 (23), 2125-2134, 2020202
31
2020
Dynamic role of the G protein in stabilizing the active state of the adenosine A2A receptor
S Lee, AK Nivedha, CG Tate, N VaidehiStructure (4), 703-712. e3, 2019201
27
2019
Identification of an alternating-access dynamics mutant of EmrE with impaired transport
C Wu, SA Wynne, NE Thomas, EM Uhlemann, CG Tate, ...Journal of molecular biology 431 (15), 2777-2789, 2019201
17
2019
Machine learning for prioritization of thermostabilizing mutations for G-protein coupled receptors
S Muk, S Ghosh, S Achuthan, X Chen, XJ Yao, M Sandhu, MC Griffor, ...Biophysical journal 117 (11), 2228-2239, 2019201
13
2019
Expression, purification and crystallisation of the adenosine A2A receptor bound to an engineered mini G protein
B Carpenter, CG TateBio-protocol 7 (8), e2234-e2234, 2017201
11
2017

Referred From: https://scholar.google.com/citations?hl=en&user=-Kt1Q0UAAAAJ

Cited by
Citations 18016
h-index 65
i10-index 118
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