Author

Bo Liang

Associate Professor, Emory University School of Medicine - Cited by 2,017 - Biochemistry - Structural biology - RNA biology - Virology - Neurobiology

Biography

Dr. Bo Liang is an Assistant Professor in the Department of Biochemistry at Emory University School of Medicine and the Co-Scientific Director of the Robert P. Apkarian Integrated Electron Microscopy Core (IEMC) at Emory University. Dr. Liang is also the Co-Director of the Biochemistry Departmental Seminar Program. Dr. Liang serves on the Department of Biochemistry Recruitment Committee and the Executive Committee of the Microbiology and Molecular Genetics (MMG) Graduate Program at Emory University.
Title
Cited by
Year
Structure of the L protein of vesicular stomatitis virus from electron cryomicroscopy
B Liang, Z Li, S Jenni, AA Rahmeh, BM Morin, T Grant, N Grigorieff, ...Cell 162 (2), 314-327, 2015201
241
2015
Modulation of neuronal activity by phosphorylation of the K–Cl cotransporter KCC2
KT Kahle, TZ Deeb, M Puskarjov, L Silayeva, B Liang, K Kaila, SJ MossTrends in neurosciences 36 (12), 726-737, 2013201
209
2013
Genetically encoded impairment of neuronal KCC 2 cotransporter function in human idiopathic generalized epilepsy
KT Kahle, ND Merner, P Friedel, L Silayeva, B Liang, A Khanna, Y Shang, ...EMBO reports 15 (7), 766-774, 2014201
175
2014
The basis of a more contagious 501Y. V1 variant of SARS-CoV-2
H Liu, Q Zhang, P Wei, Z Chen, K Aviszus, J Yang, W Downing, C Jiang, ...Cell Research 31 (6), 720-722, 2021202
137
2021
Molecular architecture of the vesicular stomatitis virus RNA polymerase
AA Rahmeh, AD Schenk, EI Danek, PJ Kranzusch, B Liang, T Walz, ...Proceedings of the National Academy of Sciences 107 (46), 20075-20080, 2010201
115
2010
Regulatory domain or CpG site variation in SLC12A5, encoding the chloride transporter KCC2, in human autism and schizophrenia
ND Merner, MR Chandler, C Bourassa, B Liang, AR Khanna, P Dion, ...Frontiers in cellular neuroscience 9, 386, 2015201
94
2015
Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
B Liang, J Zhou, E Kahen, RM Terns, MP Terns, H LiNature structural & molecular biology 16 (7), 740-746, 2009200
83
2009
Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function
J Duan, J Li, GL Chen, Y Ge, J Liu, K Xie, X Peng, W Zhou, J Zhong, ...Science advances 5 (7), eaaw7935, 2019201
74
2019
Substrate RNA positioning in the archaeal H/ACA ribonucleoprotein complex
B Liang, S Xue, RM Terns, MP Terns, H LiNature structural & molecular biology 14 (12), 1189-1195, 2007200
66
2007
Baicalein and baicalin inhibit SARS-CoV-2 RNA-dependent-RNA polymerase
K Zandi, K Musall, A Oo, D Cao, B Liang, P Hassandarvish, S Lan, ...Microorganisms 9 (5), 893, 2021202
64
2021
Critical phosphoprotein elements that regulate polymerase architecture and function in vesicular stomatitis virus
AA Rahmeh, B Morin, AD Schenk, B Liang, BS Heinrich, V Brusic, T Walz, ...Proceedings of the National Academy of Sciences 109 (36), 14628-14633, 2012201
61
2012
Cryo-EM structure of the respiratory syncytial virus RNA polymerase
D Cao, Y Gao, C Roesler, S Rice, P D’Cunha, L Zhuang, J Slack, ...Nature communications 11 (1), 368, 2020202
59
2020
Repurposing nucleoside analogs for human coronaviruses
K Zandi, F Amblard, K Musall, J Downs-Bowen, R Kleinbard, A Oo, D Cao, ...Antimicrobial Agents and Chemotherapy 65 (1), 10.1128/aac. 016-20, 2020202
52
2020
Peripheral motor neuropathy is associated with defective kinase regulation of the KCC3 cotransporter
KT Kahle, B Flores, D Bharucha-Goebel, J Zhang, S Donkervoort, ...Science signaling 9 (439), ra77-ra77, 2016201
48
2016
Structure of the vesicular stomatitis virus L protein in complex with its phosphoprotein cofactor
S Jenni, LM Bloyet, R Diaz-Avalos, B Liang, SPJ Whelan, N Grigorieff, ...Cell Reports 30 (1), 53-60. e5, 2020202
47
2020
An In Vitro RNA Synthesis Assay for Rabies Virus Defines Ribonucleoprotein Interactions Critical for Polymerase Activity
B Morin, B Liang, E Gardner, RA Ross, SPJ WhelanJournal of virology 91 (1), 10.1128/jvi. 01508-16, 2017201
31
2017
The basis of a more contagious 501Y
H Liu, Q Zhang, P Wei, Z Chen, K Aviszus, J Yang, W Downing, ...V1 variant of SARS-COV-2. bioRxiv 2, 2021202
30
2021
Structures of the Mononegavirales Polymerases
B LiangJournal of Virology 94 (22), 10.1128/jvi. 00175-20, 2020202
29
2020
Long-distance placement of substrate RNA by H/ACA proteins
B Liang, EJ Kahen, K Calvin, J Zhou, M Blanco, H LiRna 14 (10), 2086-2094, 2008200
26
2008
Structures of ribonucleoprotein particle modification enzymes
B Liang, H LiQuarterly reviews of biophysics 44 (1), 95-122, 2011201
26
2011