Author

Timothy M Palmer

Professor of Cardiovascular Biology, Hull York Medical School, University of Hull - Cited by 4,844 - Molecular Pharmacology - Cell Signalling

Biography

Graduated with BSc(Hons) in Biochemistry in 1987, the University of Manchester PhD in Biochemistry, 1991, University of Glasgow 1997-2014: Lecturer (1997-2004), worked as a Senior Lecturer (2004-2008) and Reader (2008-2014) in University of Glasgow, Scotland, UK 1991-1997: Postdoctoral Research Associate and American Heart Association Research Fellow, Duke University Medical Centre, Durham, North Carolina, USA 2015 – present: Honorary Senior Research Fellow, Institute of Cardiovascular & Medical Sciences, University of Glasgow, Scotland, UK.  
Title
Cited by
Year
Exploiting the anti-inflammatory effects of AMP-activated protein kinase activation
IP Salt, TM PalmerExpert opinion on investigational drugs 21 (8), 1155-1167, 2012201
142
2012
Anti-Inflammatory and Immunosuppressive Effects of the A2A Adenosine Receptor
GR Milne, TM PalmerThe Scientific World Journal 11, 320-339, 2011201
131
2011
Targeting SOCS proteins to control JAK-STAT signalling in disease
GA Durham, JJL Williams, MT Nasim, TM PalmerTrends in pharmacological sciences 40 (5), 298-308, 2019201
110
2019
Regulation of cell survival by sphingosine-1-phosphate receptor S1P1 via reciprocal ERK-dependent suppression of Bim and PI-3-kinase/protein kinase C-mediated upregulation of Mcl-1
C Rutherford, S Childs, J Ohotski, L McGlynn, M Riddick, S MacFarlane, ...Cell death & disease 4 (11), e927-e927, 2013201
88
2013
Activation of AMP-activated protein kinase rapidly suppresses multiple pro-inflammatory pathways in adipocytes including IL-1 receptor-associated kinase-4 phosphorylation
SJ Mancini, AD White, S Bijland, C Rutherford, D Graham, EA Richter, ...Molecular and cellular endocrinology 440, 44-56, 2017201
87
2017
The future of EPAC-targeted therapies: agonism versus antagonism
E Parnell, TM Palmer, SJ YarwoodTrends in pharmacological sciences 36 (4), 203-214, 2015201
86
2015
Identification of myeloid cells in the human enthesis as the main source of local IL-23 production
C Bridgewood, A Watad, T Russell, TM Palmer, H Marzo-Ortega, A Khan, ...Annals of the rheumatic diseases 78 (7), 929-933, 2019201
82
2019
Phosphorylation of Janus kinase 1 (JAK1) by AMP-activated protein kinase (AMPK) links energy sensing to anti-inflammatory signaling
C Rutherford, C Speirs, JJL Williams, MA Ewart, SJ Mancini, SA Hawley, ...Science signaling 9 (453), ra109-ra109, 2016201
80
2016
β1-Adrenergic Receptor and Sphingosine-1-Phosphate Receptor 1 (S1PR1) Reciprocal Downregulation Influences Cardiac Hypertrophic Response and …
A Cannavo, G Rengo, D Liccardo, G Pagano, C Zincarelli, MC De Angelis, ...Circulation 128 (15), 1612-1622, 2013201
76
2013
Regulation of the inflammatory response of vascular endothelial cells by EPAC1
E Parnell, BO Smith, TM Palmer, A Terrin, M Zaccolo, SJ YarwoodBritish journal of pharmacology 166 (2), 434-446, 2012201
67
2012
Protein kinase C phosphorylates AMP-activated protein kinase α1 Ser487
HR Heathcote, SJ Mancini, A Strembitska, K Jamal, JA Reihill, TM Palmer, ...Biochemical journal 473 (24), 4681-4697, 2016201
58
2016
Extracellular adenosine sensing—a metabolic cell death priming mechanism downstream of p53
JS Long, D Crighton, J O’Prey, G MacKay, L Zheng, TM Palmer, E Gottlieb, ...Molecular cell 50 (3), 394-406, 2013201
55
2013
Cavin-1: caveolae-dependent signalling and cardiovascular disease
JJL Williams, TM PalmerBiochemical Society Transactions 42 (2), 284-288, 2014201
48
2014
41
2014
Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability
JJL Williams, N Alotaiq, W Mullen, R Burchmore, L Liu, GS Baillie, ...Nature communications 9 (1), 168, 2018201
30
2018
Linking energy sensing to suppression of JAK-STAT signalling: a potential route for repurposing AMPK activators?
C Speirs, JJL Williams, K Riches, IP Salt, TM PalmerPharmacological Research 128, 88-100, 2018201
30
2018
Unbiased identification of substrates for the Epac1-inducible E3 ubiquitin ligase component SOCS-3
JJL Williams, TM PalmerBiochemical society transactions 40 (1), 5-8, 2012201
21
2012