Author

Alexander Kleger

Unknown affiliation - Cited by 5,606

Biography

I am a clinical senior physician in Station M1A Ulm University Hospital in August 2013, I hold a Specialist certification in internal medicine and gastroenterology in August 2013 done habilitation in internal medicine “Stem cell differentiation and cellular reprogramming as clinically relevant model systems” form 2013 appointed as head Pankreatologie and coordinator "AG pancreas", University of Ulm. Awarded as Rising Star Award, “Pancreatic cancer and stem cells”, UEG 2018 and rewarded with Top Abstract Price for United European Gastroenterology, € 10,000 by the United European Gastroenterology Travel Award for submitted abstract.
Title
Cited by
Year
Spike residue 403 affects binding of coronavirus spikes to human ACE2
F Zech, D Schniertshauer, C Jung, A Herrmann, A Cordsmeier, Q Xie, ...Nature Communications 12 (1), 6855, 2021202
17
2021
Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation
S Heller, Z Li, Q Lin, R Geusz, M Breunig, M Hohwieler, X Zhang, GG Nair, ...Communications biology 4 (1), 1298, 2021202
13
2021
Perioperative or only adjuvant gemcitabine plus nab-paclitaxel for resectable pancreatic cancer (NEONAX)—a randomized phase II trial of the AIO pancreatic cancer group
T Seufferlein, W Uhl, M Kornmann, H Algül, H Friess, A König, M Ghadimi, ...Annals of Oncology 34 (1), 91-100, 2023202
12
2023
Differentiation of human pluripotent stem cells into pancreatic duct-like organoids
M Breunig, J Merkle, MK Melzer, S Heller, T Seufferlein, M Meier, ...STAR protocols 2 (4), 100913, 2021202
12
2021
Organoids at the PUB: the porcine urinary bladder serves as a pancreatic niche for advanced cancer modeling
MK Melzer, M Breunig, F Arnold, F Wezel, A Azoitei, E Roger, J Krüger, ...Advanced Healthcare Materials 11 (11), 2102345, 2022202
7
2022
Homologous recombination deficiency is inversely correlated with microsatellite instability and identifies immunologically cold tumors in most cancer types
J Budczies, K Kluck, S Beck, I Ourailidis, M Allgäuer, M Menzel, D Kazdal, ...The Journal of Pathology: Clinical Research 8 (4), 371-382, 2022202
6
2022
High temporal resolution proteome and phosphoproteome profiling of stem cell-derived hepatocyte development
J Krumm, K Sekine, P Samaras, A Brazovskaja, M Breunig, R Yasui, ...Cell reports 38 (13), 2022202
6
2022
COVID-19 and diabetes—where are we now?
R Groß, A KlegerNature Metabolism (12), 1611-1613, 2022202
4
2022
Impaired regulation of PMCA activity by defective CFTR expression promotes epithelial cell damage in alcoholic pancreatitis and hepatitis
T Madácsy, Á Varga, N Papp, B Tél, P Pallagi, V Szabó, A Kiss, J Fanczal, ...Cellular and Molecular Life Sciences 79 (5), 265, 2022202
4
2022
Highly efficient cardiac differentiation and maintenance by thrombin-coagulated fibrin hydrogels enriched with decellularized porcine heart extracellular matrix
F Navaee, P Renaud, A Kleger, T BraschlerInternational Journal of Molecular Sciences 2 (3), 282, 2023202
4
2023
The selective 5-HT1A agonist SR57746A protects intestinal epithelial cells and enteric glia cells and promotes mucosal recovery in experimental colitis
J Walldorf, M Porzner, M Neumann, G Joodi, JH Niess, G von Boyen, ...Inflammatory Bowel Diseases 28 (), 42-4, 2022202
3
2022
A Three-Dimensional Engineered Cardiac In Vitro Model: Controlled Alignment of Cardiomyocytes in 3D Microphysiological Systems
F Navaee, N Khornian, D Longet, S Heub, S Boder-Pasche, G Weder, ...Cells 1 (4), 576, 030
2
2023
Functional IKK/NF-κB signaling in pancreatic stellate cells is essential to prevent autoimmune pancreatitis
LK Chan, M Tsesmelis, M Gerstenlauer, F Leithäuser, A Kleger, LD Frick, ...Communications Biology 5 (1), 509, 0
2
2022
Functional genomic screening in human pluripotent stem cells reveals new roadblocks in early pancreatic endoderm formation
J Krüger, M Breunig, LP Pasquini, M Morawe, A Groß, F Arnold, R Russell, ...Cells 11 (3), 58, 0
2
2022
Protocol to use de-epithelialized porcine urinary bladder as a tissue scaffold for propagation of pancreatic cells
MK Melzer, M Breunig, P Lopatta, M Hohwieler, S Merz, A Azoitei, ...STAR protocols 3 (4), 101869, 0
2
2022
State-matched organoid models to fight pancreatic cancer
MK Melzer, E Roger, A KlegerTrends in Cancer, 2022202
1
2022
Abstract B035: CXCL12/CXCR4 signaling enhances and sustains migrating cancer stem cells via BMI1 in pancreatic ductal adenocarcinomas
Abstract B035: CXCL2/CXCR4 signaling enhances and sustains migrating cancer stem cells via BMI in pancreatic ductal adenocarcinomasK Tiwary, A Lahusen, S Inaas, S Hauff, K Walter, A Kleger, T Seufferlein, ...Cancer Research 83 (2_Supplement_2), B035-B035, 2023202
1
2023