Author

Stephen A. Spector

Distinguished Professor of Pediatrics - Cited by 56,190 - HIV - AIDS - autophagy - pharmacogenetics - continental ancestry

Biography

Dr. Spector, a world leader in HIV research for more than 25 years, is Distinguished Professor of Pediatrics, the Chief of the Division of Pediatric Infectious Diseases and Director of the UCSD Mother-Child-Adolescent HIV Program. His research has used molecular and Immunologic approaches to study host-virus interactions of human cytomegalovirus (CMV) and human immunodeficiency virus type-1 (HIV-1) with a particular emphasis developing novel approaches for the detection, treatment and eradication of persistent viruses. Current CMV related research is examining the role of CMV in endothelial cell inflammation and the development of cardiovascular diseases.
Title
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...autophagy 17 (1), 1-382, 202112154202
12154
2021
Efficacy and safety of the mRNA-1273 SARS-CoV-2 vaccine
LR Baden, HM El Sahly, B Essink, K Kotloff, S Frey, R Novak, D Diemert, ...New England journal of medicine 384 (5), 403-416, 2021202
8465
2021
Immune correlates analysis of the mRNA-1273 COVID-19 vaccine efficacy clinical trial
PB Gilbert, DC Montefiori, AB McDermott, Y Fong, D Benkeser, W Deng, ...Science 375 (6576), 43-50, 2022202
720
2022
Vitamin D status and risk of incident tuberculosis disease: A nested case-control study, systematic review, and individual-participant data meta-analysis
O Aibana, CC Huang, S Aboud, A Arnedo-Pena, MC Becerra, ...PLoS medicine 16 (9), e1002907, 2019201
120
2019
SARS-CoV-2, SARS-CoV-1, and HIV-1 derived ssRNA sequences activate the NLRP3 inflammasome in human macrophages through a non-classical pathway
GR Campbell, RK To, J Hanna, SA SpectorIscience 24 (4), 2021202
85
2021
Human immunodeficiency virus Type‐1 single‐stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia
P Rawat, C Teodorof‐Diedrich, SA SpectorGlia 67 (5), 802-824, 2019201
55
2019
TREM-1 protects HIV-1-infected macrophages from apoptosis through maintenance of mitochondrial function
GR Campbell, RK To, SA SpectorMBio 10 (6), 10.1128/mbio. 02638-19, 2019201
35
2019
Selective cell death of latently HIV-infected CD4+ T cells mediated by autosis inducing nanopeptides
G Zhang, BT Luk, X Wei, GR Campbell, RH Fang, L Zhang, SA SpectorCell death & disease 10 (6), 419, 2019201
34
2019
Human papillomavirus antibody levels and quadrivalent vaccine clinical effectiveness in perinatally human immunodeficiency virus–infected and exposed, uninfected youth
AB Moscicki, B Karalius, K Tassiopoulos, TJ Yao, DL Jacobson, K Patel, ...Clinical Infectious Diseases 69 (7), 1183-1191, 2019201
31
2019
CD4+ T Cell-Mimicking Nanoparticles Broadly Neutralize HIV-1 and Suppress Viral Replication through Autophagy
G Zhang, GR Campbell, Q Zhang, E Maule, J Hanna, W Gao, L Zhang, ...MBio 11 (5), 10.1128/mbio. 00903-20, 2020202
30
2020
Live-attenuated vaccines prevent respiratory syncytial virus–associated illness in young children
RA Karron, JE Atwell, EJ McFarland, CK Cunningham, P Muresan, ...American journal of respiratory and critical care medicine 203 (5), 594-603, 2021202
27
2021
SMAC mimetics induce autophagy-dependent apoptosis of HIV-1-infected macrophages
GR Campbell, RK To, G Zhang, SA SpectorCell death & disease 11 (7), 590, 2020202
21
2020
Live respiratory syncytial virus attenuated by M2-2 deletion and stabilized temperature sensitivity mutation 1030s is a promising vaccine candidate in children
EJ McFarland, RA Karron, P Muresan, CK Cunningham, J Libous, ...The Journal of infectious diseases 221 (4), 534-543, 2020202
19
2020
Quantitative human immunodeficiency virus (HIV)-1 antibodies correlate with plasma HIV-1 RNA and cell-associated DNA levels in children on antiretroviral therapy
M McManus, J Henderson, A Gautam, R Brody, ER Weiss, D Persaud, ...Clinical Infectious Diseases 68 (10), 25-32, 2019201
17
2019
Safety and efficacy at 240 weeks of different raltegravir formulations in children with HIV-1: a phase 1/2 open label, non-randomised, multicentre trial
S Nachman, C Alvero, H Teppler, B Homony, AJ Rodgers, BL Graham, ...The Lancet HIV 5 (12), e715-e722, 2018201
17
2018
Human immunodeficiency virus type 1 and methamphetamine-mediated mitochondrial damage and neuronal degeneration in human neurons
C Teodorof-Diedrich, SA SpectorJournal of virology 94 (20), 10.1128/jvi. 00924-20, 2020202
16
2020
Pharmacokinetics and safety of early nevirapine-based antiretroviral therapy for neonates at high risk for perinatal HIV infection: a phase 1/2 proof of concept study
TD Ruel, EV Capparelli, C Tierney, BS Nelson, A Coletti, Y Bryson, ...The Lancet HIV 8 (3), e9-e157, 2021202
14
2021
DIABLO/SMAC mimetics selectively kill HIV-1-infected resting memory CD4+ T cells: a potential role in a cure strategy for HIV-1 infection
GR Campbell, SA SpectorAutophagy 15 (4), 744-746, 2019201
13
2019
Healthcare transition outcomes among young adults with perinatally acquired human immunodeficiency virus infection in the United States
K Tassiopoulos, Y Huo, K Patel, D Kacanek, S Allison, S Siminski, ...Clinical infectious diseases 71 (1), 3-141, 2020202
13
2020
Raltegravir (RAL) in neonates: Dosing, pharmacokinetics (PK), and safety in HIV-1 exposed neonates at risk of infection (IMPAACT P1110)
DF Clarke, EP Acosta, M Cababasay, J Wang, A Chain, H Teppler, ...Journal of acquired immune deficiency syndromes (1999) 84 (1), 70, 2020202
13
2020

Referred From: https://scholar.google.com/citations?hl=en&user=gsn89csAAAAJ

Cited by
Citations 56190
h-index 92
i10-index 343
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