Author

Gavin Williams

Professor of Chemistry, NC State University - Cited by 2,363 - chemical biology - synthetic biology - natural product biosynthesis - enzyme engineering - chemo-enzymatic synthesis

Biography

Dr. Gavin Williams is an Assistant Professor in the Department of Physiotherapy, University of Melbourne, Victoria, Australia. His research interest includes Speech Science, Hearing Science, etc. He has published more than 39 publications and the articles are informative and got good citations.
Title
Cited by
Year
Engineering polyketide synthases and nonribosomal peptide synthetases
GJ WilliamsCurrent opinion in structural biology 23 (4), 603-612, 2013201
109
2013
Development of transcription factor-based designer macrolide biosensors for metabolic engineering and synthetic biology
CM Kasey, M Zerrad, Y Li, TA Cropp, GJ WilliamsACS synthetic biology 7 (1), 227-239, 2018201
93
2018
Poly Specific trans-Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases
I Koryakina, J McArthur, S Randall, MM Draelos, EM Musiol, ...ACS chemical biology 8 (1), 200-208, 2013201
86
2013
Promiscuity of a modular polyketide synthase towards natural and non-natural extender units
I Koryakina, JB McArthur, MM Draelos, GJ WilliamsOrganic & biomolecular chemistry 11 (27), 4449-4458, 2013201
70
2013
Inversion of extender unit selectivity in the erythromycin polyketide synthase by acyltransferase domain engineering
I Koryakina, C Kasey, JB McArthur, AN Lowell, JA Chemler, S Li, ...ACS chemical biology 12 (1), 114-123, 2017201
68
2017
68
2011
An artificial pathway for isoprenoid biosynthesis decoupled from native hemiterpene metabolism
S Lund, R Hall, GJ WilliamsACS synthetic biology 8 (2), 232-238, 2019201
64
2019
Reprogramming acyl carrier protein interactions of an Acyl-CoA promiscuous trans-acyltransferase
Z Ye, EM Musiol, T Weber, GJ WilliamsChemistry & biology 21 (5), 636-646, 2014201
50
2014
Polyketide bioderivatization using the promiscuous acyltransferase KirCII
EM Musiol-Kroll, F Zubeil, T Schafhauser, T Härtner, A Kulik, J McArthur, ...ACS synthetic biology 6 (3), 421-427, 2017201
48
2017
Transcription factor-based biosensors: a molecular-guided approach for natural product engineering
MM Mitchler, JM Garcia, NE Montero, GJ WilliamsCurrent opinion in biotechnology 69, 172-181, 2021202
47
2021
Engineering the substrate specificity of a modular polyketide synthase for installation of consecutive non-natural extender units
E Kalkreuter, JM CroweTipton, AN Lowell, DH Sherman, GJ WilliamsJournal of the American Chemical Society 1 (5), 1961-1969, 2019201
41
2019
Engineering enzymatic assembly lines for the production of new antimicrobials
E Kalkreuter, GJ WilliamsCurrent opinion in microbiology 45, 140-148, 2018201
37
2018
Harnessing natural product assembly lines: structure, promiscuity, and engineering
CC Ladner, GJ WilliamsJournal of Industrial Microbiology and Biotechnology 43 (2-3), 371-387, 2016201
32
2016
Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli
E Kalkreuter, AM Keeler, AA Malico, KS Bingham, AK Gayen, GJ WilliamsACS synthetic biology 8 (6), 1391-1400, 191
20
2019
Intracellular Light‐Activation of Riboswitch Activity
S Walsh, L Gardner, A Deiters, GJ WilliamsChemBioChem 15 (9), 1346-1351, 2014201
19
2014
Synthetic biology enabling access to designer polyketides
AA Malico, L Nichols, GJ WilliamsCurrent opinion in chemical biology 58, 45-53, 2020202
17
2020
Cheminformatics analysis and modeling with MacrolactoneDB
PPK Zin, GJ Williams, S EkinsScientific Reports 10 (1), 6284, 2020202
15
2020
Synthetic biology, combinatorial biosynthesis, and chemo‑enzymatic synthesis of isoprenoids
AA Malico, MA Calzini, AK Gayen, GJ WilliamsJournal of Industrial Microbiology & Biotechnology: Official Journal of the …, 2020202
15
2020
Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase
E Kalkreuter, KS Bingham, AM Keeler, AN Lowell, JJ Schmidt, ...Nature communications 12 (1), 2193, 2021202
15
2021