Author

Erik Ladomersky

Postdoctoral Fellow, Northwestern University - Cited by 1,611

Biography

I have the privilege to be a Postdoctoral Fellow in the lab of Dr. Derek A. Wainwright at Northwestern University Feinberg School of Medicine. Within this lab, and through my graduate training, I have gained expertise in many techniques including: HPLC.I have pursued research in the areas of Neuro-onco-immunology, designing models to examine the mechanisms by which the aging immune system negatively affects immunotherapeutic efficacy
Title
Cited by
Year
IDO1 in cancer: a Gemini of immune checkpoints
L Zhai, E Ladomersky, A Lenzen, B Nguyen, R Patel, KL Lauing, M Wu, ...Cellular & molecular immunology 15 (5), 447-457, 2018201
254
2018
IDO1 inhibition synergizes with radiation and PD-1 blockade to durably increase survival against advanced glioblastoma
E Ladomersky, L Zhai, A Lenzen, KL Lauing, J Qian, DM Scholtens, ...Clinical cancer research 24 (11), 2559-2573, 2018201
145
2018
Infiltrating T cells increase IDO1 expression in glioblastoma and contribute to decreased patient survival
L Zhai, E Ladomersky, KL Lauing, M Wu, M Genet, G Gritsina, B Győrffy, ...Clinical Cancer Research 23 (21), 6650-6660, 2017201
131
2017
Newly diagnosed glioblastoma: a review on clinical management
RV Lukas, DA Wainwright, E Ladomersky, S Sachdev, AM Sonabend, ...Oncology (Williston Park, NY) 33 (3), 91, 2019201
117
2019
Immunosuppressive IDO in cancer: mechanisms of action, animal models, and targeting strategies
L Zhai, A Bell, E Ladomersky, KL Lauing, L Bollu, JA Sosman, B Zhang, ...Frontiers in immunology, 1185, 2020202
113
2020
ATP7A delivers copper to the lysyl oxidase family of enzymes and promotes tumorigenesis and metastasis
V Shanbhag, K Jasmer-McDonald, S Zhu, AL Martin, N Gudekar, A Khan, ...Proceedings of the National Academy of Sciences 116 (14), 6836-6841, 2019201
98
2019
The coincidence between increasing age, immunosuppression, and the incidence of patients with glioblastoma
E Ladomersky, DM Scholtens, M Kocherginsky, EA Hibler, ET Bartom, ...Frontiers in pharmacology 10, 200, 2019201
93
2019
Advanced age increases immunosuppression in the brain and decreases immunotherapeutic efficacy in subjects with glioblastoma
E Ladomersky, L Zhai, KL Lauing, A Bell, J Xu, M Kocherginsky, B Zhang, ...Clinical Cancer Research 26 (19), 5232-5245, 2020202
54
2020
Tumor cell IDO enhances immune suppression and decreases survival independent of tryptophan metabolism in glioblastoma
L Zhai, A Bell, E Ladomersky, KL Lauing, L Bollu, B Nguyen, M Genet, ...Clinical cancer research 27 (23), 6514-6528, 2021202
37
2021
Glioblastoma as an age-related neurological disorder in adults
M Kim, E Ladomersky, A Mozny, M Kocherginsky, K O’Shea, ZZ Reinstein, ...Neuro-oncology advances 3 (1), vdab125, 2021202
27
2021
A retrospective survival analysis of Glioblastoma patients treated with selective serotonin reuptake inhibitors
S Otto-Meyer, R DeFaccio, C Dussold, E Ladomersky, L Zhai, KL Lauing, ...Brain, Behavior, & Immunity-Health 2, 1000, 2020202
25
2020
The interplay among psychological distress, the immune system, and brain tumor patient outcomes
S Otto-Meyer, J Lumibao, E Kim, E Ladomersky, L Zhai, KL Lauing, ...Current opinion in behavioral sciences 28, 44-50, 2019201
23
2019
Lessons learned from rindopepimut treatment in patients with EGFRvIII-expressing glioblastoma
DC Binder, E Ladomersky, A Lenzen, L Zhai, KL Lauing, SD Otto-Meyer, ...Translational cancer research 7 (Suppl 4), S510, 181
20
2018
Quantification of IDO1 enzyme activity in normal and malignant tissues
L Zhai, E Ladomersky, A Bell, C Dussold, K Cardoza, J Qian, KL Lauing, ...Methods in enzymology 629, 235-256, 2019201
10
2019
Identification and characterization of a novel indoleamine 2, 3-Dioxygenase 1 protein degrader for glioblastoma
LR Bollu, PV Bommi, PJ Monsen, L Zhai, KL Lauing, A Bell, M Kim, ...Journal of Medicinal Chemistry 5 (23), 1542-152, 2022202
6
2022
Immu-01. Novel Rna-Targeting Strategy for Treating T Cell-Driven Immunosuppression in Human Diffuse Intrinsic Pontine Glioma
A Lenzen, KL Lauing, L Zhai, E Ladomersky, P Raman, K Rathi, RR Lulla, ...Neuro-oncology 1 (Supplement_), ii9-ii93, 01901
2
2019
Immu-24. Immunotherapeutic Nanotechnology Targeting Ido1 for Pediatric Diffuse Intrinsic Pontine Glioma
Immu-4. Immunotherapeutic Nanotechnology Targeting Ido1 for Pediatric Diffuse Intrinsic Pontine GliomaA Lenzen, L Cole, KL Lauing, L Zhai, E Ladomersky, RR Lulla, ...Neuro-Oncology 0 (Suppl ), i103, 01801
2
2018
Tumor cell IDO1 increases intratumoral immunosuppressive Tregs independent of enzyme activity
Tumor cell IDO increases intratumoral immunosuppressive Tregs independent of enzyme activityL Zhai, A Bell, J Qian, E Ladomersky, KL Lauing, DA WainwrightThe Journal of Immunology 202 (_Supplement), 37.2-37.2, 20920
1
2019
IMMU-40. Improving outcomes in older adults with glioblastoma by reversing age-related changes of the central nervous system
E Ladomersky, L Zhai, L Bollu, A Bell, K Lauing, R Lukas, D WainwrightNeuro-Oncology 22 (Suppl 2), ii3, 2020202
1
2020