Author

Cristina Bottino

University School of Medicine and Istituto G. Gaslini, Genova, Italy - Cited by 30,887 - Human Immunology - natural killer cells - cancer - immunodeficiencies

Biography

The research activity of Cristina Bottino is focused on the analysis of the molecular mechanisms regulating the immune mediated recognition of tumors and virus-infected cells in human. Since 1990 a major object of her research has been the study of the function of Natural Killer cells (NK) in physiological and pathological conditions
Title
Cited by
Year
Mesenchymal stromal cells induce peculiar alternatively activated macrophages capable of dampening both innate and adaptive immune responses
L Chiossone, R Conte, GM Spaggiari, M Serra, C Romei, F Bellora, ...Stem Cells 34 (7), 1909-1921, 2016201
171
2016
Neuroblastoma-derived TGF-β1 modulates the chemokine receptor repertoire of human resting NK cells
R Castriconi, A Dondero, F Bellora, L Moretta, A Castellano, F Locatelli, ...The Journal of Immunology 190 (10), 5321-5328, 2013201
139
2013
Natural killer cells and neuroblastoma: tumor recognition, escape mechanisms, and possible novel immunotherapeutic approaches
C Bottino, A Dondero, F Bellora, L Moretta, F Locatelli, V Pistoia, ...Frontiers in immunology 5, 56, 2014201
117
2014
PD-L1 expression in metastatic neuroblastoma as an additional mechanism for limiting immune surveillance
A Dondero, F Pastorino, M Della Chiesa, MV Corrias, F Morandi, V Pistoia, ...Oncoimmunology 5 (1), e1064578, 2016201
99
2016
Molecular mechanisms directing migration and retention of natural killer cells in human tissues
R Castriconi, P Carrega, A Dondero, F Bellora, B Casu, S Regis, ...Frontiers in immunology 9, 2324, 2018201
95
2018
TLR activation of tumor‐associated macrophages from ovarian cancer patients triggers cytolytic activity of NK cells
F Bellora, R Castriconi, A Dondero, A Pessino, A Nencioni, G Liggieri, ...European journal of immunology 44 (6), 1814-1822, 2014201
85
2014
NK cells, tumor cell transition, and tumor progression in solid malignancies: new hints for NK-based immunotherapy?
C Cantoni, L Huergo-Zapico, M Parodi, M Pedrazzi, MC Mingari, ...Journal of immunology research 2016, 2016201
80
2016
A combined immunodeficiency with severe infections, inflammation, and allergy caused by ARPC1B deficiency
S Volpi, MP Cicalese, P Tuijnenburg, ATJ Tool, E Cuadrado, ...Journal of Allergy and Clinical Immunology 143 (6), 2296-2299, 2019201
73
2019
Human NK cells and NK receptors
F Bellora, R Castriconi, A Dondero, P Carrega, A Mantovani, G Ferlazzo, ...Immunology letters 161 (2), 168-173, 2014201
69
2014
Nidogen-1 is a novel extracellular ligand for the NKp44 activating receptor
S Gaggero, M Bruschi, A Petretto, M Parodi, GD Zotto, C Lavarello, ...Oncoimmunology 7 (9), e1470730, 2018201
67
2018
KIR and KIR ligand polymorphism: a new area for clinical applications?
M Falco, L Moretta, A Moretta, C BottinoTissue Antigens 82 (6), 3-373, 2013201
63
2013
TGF-β1 Downregulates the Expression of CX3CR1 by Inducing miR-27a-5p in Primary Human NK Cells
S Regis, F Caliendo, A Dondero, B Casu, F Romano, F Loiacono, ...Frontiers in Immunology 8, 868, 2017201
57
2017
In vivo generation of decidual natural killer cells from resident hematopoietic progenitors
L Chiossone, P Vacca, P Orecchia, D Croxatto, P Damonte, S Astigiano, ...Haematologica 99 (3), 448, 2014201
52
2014
NK cell function regulation by TGF-β-induced epigenetic mechanisms
S Regis, A Dondero, F Caliendo, C Bottino, R CastriconiFrontiers in Immunology 11, 311, 2020202
51
2020
Imatinib and nilotinib off-target effects on human NK cells, monocytes, and M2 macrophages
F Bellora, A Dondero, MV Corrias, B Casu, S Regis, F Caliendo, A Moretta, ...The Journal of Immunology 199 (4), 1516-1525, 2017201
41
2017
Cell-laden hydrogel as a clinical-relevant 3D model for analyzing neuroblastoma growth, immunophenotype, and susceptibility to therapies
A Marrella, A Dondero, M Aiello, B Casu, D Olive, S Regis, C Bottino, ...Frontiers in immunology 10, 1876, 2019201
33
2019
Oxysterol mixture and, in particular, 27‐hydroxycholesterol drive M2 polarization of human macrophages
B Marengo, F Bellora, R Ricciarelli, C De Ciucis, AL Furfaro, R Leardi, ...BioFactors 42 (1), 80-92, 2016201
29
2016
NK cells and multiple myeloma-associated endothelial cells: molecular interactions and influence of IL-27
A Dondero, B Casu, F Bellora, A Vacca, A De Luisi, MA Frassanito, ...Oncotarget 8 (), 35088, 2017201
21
2017
Diagnosing XLP1 in patients with hemophagocytic lymphohistiocytosis
R Meazza, C Tuberosa, V Cetica, M Falco, S Parolini, S Grieve, ...Journal of allergy and clinical immunology 134 (6), 1381-1387. e7, 2014201
21
2014
Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients
R Meazza, M Falco, S Marcenaro, F Loiacono, P Canevali, F Bellora, ...European Journal of Immunology 47 (6), 1051-1061, 2017201
21
2017

Referred From: https://scholar.google.com/citations?user=wB4fKQcAAAAJ&hl=it

Cited by
Citations 30887
h-index 86
i10-index 160
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