Author

Mahmoud El Hefnawi

Professor, The National Research Centre, biomedical informatics and chemoinformatics group leader - Cited by 1,691 - gene therapy - machine learning - computer aided drug design - computational biology - biomedical informatics as well as bioinforma

Biography

Dr. Mahmoud El Hefnawi  is currently working at  National Research  Department. Mahmoud El Hefnawi  is research interests includes  National Research  in Drug design.Mahmoud El Hefnawi serving as an editorial member and reviewer of several international reputed journals. Mahmoud El Hefnawi  has successfully completed his Administrative responsibilities. Mahmoud El Hefnawi  has authored of many research articles/books related to Medicine.
Title
Cited by
Year
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa
E Wilkinson, M Giovanetti, H Tegally, JE San, R Lessells, D Cuadros, ...Science 374 (6566), 423-431, 2021202
141
2021
Telaprevir is a potential drug for repurposing against SARS-CoV-2: computational and in vitro studies
A Mahmoud, A Mostafa, AA Al-Karmalawy, A Zidan, HS Abulkhair, ...Heliyon 7 (9), 2021202
52
2021
Performance of machine learning approaches on prediction of esophageal varices for Egyptian chronic hepatitis C patients
SM Abd El-Salam, MM Ezz, S Hashem, W Elakel, R Salama, ...Informatics in Medicine Unlocked 17, 100267, 2019201
44
2019
Evaluation of computational techniques for predicting non-synonymous single nucleotide variants pathogenicity
MS Hassan, AA Shaalan, MI Dessouky, AE Abdelnaiem, M ElHefnawiGenomics 111 (4), 869-882, 2019201
43
2019
The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance
H Tegally, JE San, M Cotten, M Moir, B Tegomoh, G Mboowa, DP Martin, ...Science 378 (6615), eabq5358, 2022202
42
2022
Machine learning prediction models for diagnosing hepatocellular carcinoma with HCV-related chronic liver disease
S Hashem, M ElHefnawi, S Habashy, M El-Adawy, G Esmat, W Elakel, ...Computer methods and programs in biomedicine 196, 105551, 2020202
41
2020
A review study: computational techniques for expecting the impact of non-synonymous single nucleotide variants in human diseases
MS Hassan, AA Shaalan, MI Dessouky, AE Abdelnaiem, M ElHefnawiGene 680, 20-33, 2019201
38
2019
In silico and in vivo evaluation of SARS-CoV-2 predicted epitopes-based candidate vaccine
MM Shehata, SH Mahmoud, M Tarek, AA Al-Karmalawy, A Mahmoud, ...Molecules 26 (20), 6182, 2021202
22
2021
Co-regulatory network of oncosuppressor miRNAs and transcription factors for pathology of human hepatic cancer stem cells (HCSC)
RH Mohamed, N Abu-Shahba, M Mahmoud, AMH Abdelfattah, W Zakaria, ...Scientific reports 9 (1), 5564, 191
20
2019
Systematic auditing is essential to debiasing machine learning in biology
FE Eid, HA Elmarakeby, YA Chan, N Fornelos, M ElHefnawi, ...Communications biology 4 (1), 183, 2021202
15
2021
Effect of tumor suppressor miR-34a loaded on ZSM-5 nanozeolite in hepatocellular carcinoma: In vitro and in vivo approach
Z Salah, EM Abd El Azeem, HF Youssef, AM Gamal-Eldeen, AR Farrag, ...Current Gene Therapy 19 (5), 342-354, 2019201
14
2019
Expression profiling and analysis of some miRNAs in subcutaneous white adipose tissue during development of obesity
EM Youssef, AM Elfiky, N Abu-Shahba, MM ElhefnawiGenes & Nutrition 15 (1), 1-14, 2020202
12
2020
Altered expression of WFS1 and NOTCH2 genes associated with diabetic nephropathy in T2DM patients
SA Sharaf, NA Kantoush, DF Ayoub, AA Ibrahim, AA Abdelaal, RA Aziz, ...Diabetes Research and Clinical Practice 140, 304-313, 2018201
12
2018
MicroRNA-150 down regulation in acute myeloid leukaemia patients and its prognostic implication
DA Abdelhalim, BM Elgamal, MR ElKafoury, NM Hassan, MM Hussein, ...Open access Macedonian journal of medical sciences 6 (), 1993, 2018201
11
2018
Impact of type 2 diabetes mellitus on the immunoregulatory characteristics of adipose tissue-derived mesenchymal stem cells
N Abu-Shahba, M Mahmoud, AM El-Erian, MI Husseiny, G Nour-Eldeen, ...The international journal of biochemistry & cell biology 140, 6072, 2021202
10
2021
The promise of miRNA replacement therapy for hepatocellular carcinoma
M Elhefnawi, Z Salah, B SolimanCurrent Gene Therapy 19 (5), 290-304, 2019201
10
2019
Whole genome sequencing and bioinformatics analysis of two Egyptian genomes
M ElHefnawi, S Jeon, Y Bhak, A ElFiky, A Horaiz, JH Jun, H Kim, J BhakGene 66, 129-134, 20120
8
2018
Targeted delivery of miR-218 via decorated hyperbranched polyamidoamine for liver cancer regression
AM Elfiky, RH Mohamed, FEZ Abd EL-Hakam, MA Yassin, M ElHefnawiInternational Journal of Pharmaceutics 10, 12125, 2021202
6
2021
Integrative assessment of CIP2A overexpression and mutational effects in human malignancies identifies possible deleterious variants
MM Tarek, A Yahia, MM El-Nakib, M ElhefnawiComputers in Biology and Medicine 139, 10498, 2021202
6
2021