Author

George D Geromichalos

Aristotle University of Thessaloniki, Chemistry Dept - Cited by 2,404 - Drug design - anticancer - molecular modeling

Biography

Dr. George Geromichalos is currently head in Cell Culture Molecular Modeling & Drug Design Dept. of Symeonidion Research Center, Theagenion Cancer Hospital at Thessaloniki, Greece.  He  received Ph.D. degree in Biochemistry and Quantum Chemistry in 2003 from Faculty of Chemistry, Aristotle University of Thessaloniki.  His  areas of research include research & development of new drugs with improved toxicity pattern, increased anticancer activity and better selectivity, through modifying the structure of known functional molecules, study of signal transduction pathways and their relation to cytotoxicity or apoptosis.  He has authored and co-authored over 44 peer-reviewed journal articles and over 190 conference papers. 
Title
Cited by
Year
Saffron as a source of novel acetylcholinesterase inhibitors: molecular docking and in vitro enzymatic studies
GD Geromichalos, FN Lamari, MA Papandreou, DT Trafalis, M Margarity, ...Journal of agricultural and food chemistry 60 (24), 6131-6138, 2012201
165
2012
Novel cinnamic acid derivatives as antioxidant and anticancer agents: Design, synthesis and modeling studies
E Pontiki, D Hadjipavlou-Litina, K Litinas, G GeromichalosMolecules 19 (7), 9655-9674, 2014201
139
2014
Anticarcinogenic activity of polyphenolic extracts from grape stems against breast, colon, renal and thyroid cancer cells
D Sahpazidou, GD Geromichalos, D Stagos, A Apostolou, ...Toxicology letters 230 (2), 218-224, 2014201
131
2014
Synthesis, structural characterization and biological studies of the triphenyltin (IV) complex with 2-thiobarbituric acid
VI Balas, II Verginadis, GD Geromichalos, N Kourkoumelis, L Male, ...European journal of medicinal chemistry 46 (7), 2835-2844, 2011201
96
2011
Cobalt (II) complexes with the quinolone antimicrobial drug oxolinic acid: structure and biological perspectives
EP Irgi, GD Geromichalos, S Balala, J Kljun, S Kalogiannis, ...RSC Advances 5 (46), 36353-36367, 2015201
55
2015
A novel silver iodide metalo-drug: Experimental and computational modelling assessment of its interaction with intracellular DNA, lipoxygenase and glutathione
CN Banti, L Kyros, GD Geromichalos, N Kourkoumelis, M Kubicki, ...European journal of medicinal chemistry 77, 388-399, 2014201
46
2014
Preparation and pharmacochemical evaluation of mixed ligand copper (II) complexes with triethanolamine and thiophenyl-2 saturated carboxylic acids
Z Boulsourani, GD Geromichalos, K Repana, E Yiannaki, V Psycharis, ...Journal of Inorganic Biochemistry 105 (6), 839-849, 2011201
42
2011
Safranal, a Crocus sativus L constituent suppresses the growth of K-562 cells of chronic myelogenous leukemia. In silico and in vitro study
GD Geromichalos, T Papadopoulos, D Sahpazidou, Z SinakosFood and chemical toxicology 74, 45-50, 2014201
39
2014
Overview on the current status of virtual high-throughput screening and combinatorial chemistry approaches in multi-target anticancer drug discovery; Part I
GD Geromichalos, CE Alifieris, EG Geromichalou, DT TrafalisJ buon 21 (4), 764-79, 2016201
34
2016
Palladium (II) complexes with salicylaldehyde ligands: Synthesis, characterization, structure, in vitro and in silico study of the interaction with calf-thymus DNA and albumins
A Zianna, GD Geromichalos, AG Hatzidimitriou, E Coutouli-Argyropoulou, ...Journal of inorganic biochemistry 194, 85-96, 2019201
34
2019
A palladium (II) complex with the Schiff base 4-chloro-2-(N-ethyliminomethyl)-phenol: Synthesis, structural characterization, and in vitro and in silico biological activity studies
A Zianna, GD Geromichalos, A Pekou, AG Hatzidimitriou, ...Journal of Inorganic Biochemistry 199, 110792, 2019201
30
2019
Effect of cobalt (II) complexes with dipyridylamine and salicylaldehydes on cultured tumor and non-tumor cells: Synthesis, crystal structure investigations and biological activity
M Lalia-Kantouri, M Gdaniec, T Choli-Papadopoulou, A Badounas, ...Journal of inorganic biochemistry 117, 25-34, 2012201
29
2012
Structural and in vitro biological studies of organotin (IV) precursors; selective inhibitory activity against human breast cancer cells, positive to estrogen receptors
VI Balas, CN Banti, N Kourkoumelis, SK Hadjikakou, GD Geromichalos, ...Australian Journal of Chemistry 65 (12), 1625-1637, 2012201
28
2012
In vitro and in silico study of the biological activity of manganese (III) inverse-[9-MC-3]-metallacrowns and manganese (II) complexes with the anti-inflammatory drugs …
GD Geromichalos, A Tarushi, K Lafazanis, AA Pantazaki, ...Journal of inorganic biochemistry 187, 41-55, 2018201
23
2018
Interaction of ZnO nanostructures with proteins: In vitro fibrillation/antifibrillation studies and in silico molecular docking simulations
K Giannousi, G Geromichalos, D Kakolyri, S Mourdikoudis, ...ACS Chemical Neuroscience 11 (3), 436-444, 2020202
23
2020
Manganese coordination compounds of mefenamic acid: In vitro screening and in silico prediction of biological activity
A Tarushi, GD Geromichalos, DP Kessissoglou, G PsomasJournal of Inorganic Biochemistry 190, 1-14, 2019201
23
2019
Rational design and structure–activity relationship studies of quercetin–amino acid hybrids targeting the anti-apoptotic protein Bcl-xL
TF Kellici, MV Chatziathanasiadou, MS Lee, N Sayyad, EG Geromichalou, ...Organic & biomolecular chemistry 15 (37), 7956-7976, 2017201
22
2017
Oleuropein is a natural inhibitor of PAI-1-mediated proliferation in human ER-/PR-breast cancer cells
EE Tzekaki, G Geromichalos, SN Lavrentiadou, MP Tsantarliotou, ...Breast Cancer Research and Treatment 186, 305-316, 212
20
2021
Synthesis, structure elucidation and biological evaluation of triple bridged dinuclear copper (II) complexes as anticancer and antioxidant/anti-inflammatory agents
Z Boulsourani, S Katsamakas, GD Geromichalos, V Psycharis, ...Materials Science and Engineering: C 76, 1026-1040, 171
20
2017
A step-ladder manganese (iii) metallacrown hosting mefenamic acid and a manganese (ii)–mefanamato complex: synthesis, characterization and cytotoxic activity
A Tarushi, GD Geromichalos, K Lafazanis, CP Raptopoulou, V Psycharis, ...New Journal of Chemistry 42 (9), 6955-6967, 202
18
2018

Referred From: https://scholar.google.gr/citations?user=yOKR33cAAAAJ&hl=en

Cited by
Citations 2404
h-index 25
i10-index 47
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