Author

Yanming Wang

Department of Biochemistry and Molecular Biology - Cited by 15,781 - histone - histone modifications - epigenetics - transcription - chromatin

Biography

Dr. Yanming Wang is Associate Professor of Radiology Chemistry and Biomedical Engineering at Case Western Reserve University He has received a PhD in Chemistry from the Swiss Federal Institute of Technology in Zurich Dr Wang’s research is focused on the development of molecular probes for imaging guided diagnosis and efficacy evaluation of therapeutic treatments in neurological diseases and cancer. Since 1998, Dr. Wang’s research has been focused on the development of molecular probes for imaging-guided diagnosis and efficacy evaluation of therapeutic treatments in neurological diseases and cancer, which are based on a variety of imaging modalities PET, SPECT, NIRF.
Title
Cited by
Year
Histone hypercitrullination mediates chromatin decondensation and neutrophil extracellular trap formation
Y Wang, M Li, S Stadler, S Correll, P Li, D Wang, R Hayama, L Leonelli, ...Journal of Cell Biology 184 (2), 205-213, 2009200
1372
2009
PAD4 is essential for antibacterial innate immunity mediated by neutrophil extracellular traps
P Li, M Li, MR Lindberg, MJ Kennett, N Xiong, Y WangJournal of Experimental Medicine 207 (9), 1853-1862, 2010201
1308
2010
Human PAD4 regulates histone arginine methylation levels via demethylimination
Y Wang, J Wysocka, J Sayegh, YH Lee, JR Perlin, L Leonelli, ...Science 306 (5694), 279-283, 2004200
1155
2004
Diabetes primes neutrophils to undergo NETosis, which impairs wound healing
SL Wong, M Demers, K Martinod, M Gallant, Y Wang, AB Goldfine, ...Nature medicine 21 (7), 815-819, 2015201
860
2015
Neutrophil extracellular traps promote the development and progression of liver metastases after surgical stress
S Tohme, HO Yazdani, AB Al-Khafaji, AP Chidi, P Loughran, K Mowen, ...Cancer research 76 (6), 1367-1380, 2016201
505
2016
Neutrophil histone modification by peptidylarginine deiminase 4 is critical for deep vein thrombosis in mice
K Martinod, M Demers, TA Fuchs, SL Wong, A Brill, M Gallant, J Hu, ...Proceedings of the National Academy of Sciences 110 (21), 8674-8679, 2013201
488
2013
Statins enhance formation of phagocyte extracellular traps
OA Chow, M von Köckritz-Blickwede, AT Bright, ME Hensler, ...Cell host & microbe 8 (5), 445-454, 2010201
430
2010
PAD4 mediated histone hypercitrullination induces heterochromatin decondensation and chromatin unfolding to form neutrophil extracellular trap-like structures
M Leshner, S Wang, C Lewis, H Zheng, XA Chen, L Santy, Y WangFrontiers in immunology 3, 307, 2012201
408
2012
Damage‐associated molecular pattern–activated neutrophil extracellular trap exacerbates sterile inflammatory liver injury
H Huang, S Tohme, AB Al‐Khafaji, S Tai, P Loughran, L Chen, S Wang, ...Hepatology 62 (2), 600-614, 2015201
375
2015
Peptidylarginine deiminases in citrullination, gene regulation, health and pathogenesis
S Wang, Y WangBiochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1829 (10 …, 2013201
296
2013
Small molecules efficiently reprogram human astroglial cells into functional neurons
L Zhang, JC Yin, H Yeh, NX Ma, G Lee, XA Chen, Y Wang, L Lin, L Chen, ...Cell stem cell 17 (6), 735-747, 2015201
267
2015
Regulation of p53 target gene expression by peptidylarginine deiminase 4
P Li, H Yao, Z Zhang, M Li, Y Luo, PR Thompson, DS Gilmour, Y WangMolecular and cellular biology 28 (15), 4745-4758, 2008200
262
2008
VWF-mediated leukocyte recruitment with chromatin decondensation by PAD4 increases myocardial ischemia/reperfusion injury in mice
AS Savchenko, JI Borissoff, K Martinod, SF De Meyer, M Gallant, ...Blood, The Journal of the American Society of Hematology 123 (1), 141-148, 2014201
242
2014
Priming of neutrophils toward NETosis promotes tumor growth
M Demers, SL Wong, K Martinod, M Gallant, JE Cabral, Y Wang, ...Oncoimmunology 5 (5), e1134073, 6
201
2016
PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock
K Martinod, TA Fuchs, NL Zitomersky, SL Wong, M Demers, M Gallant, ...Blood, The Journal of the American Society of Hematology 125 (12), 1948-1956, 2015201
193
2015
Structural and histone binding ability characterizations of human PWWP domains
H Wu, H Zeng, R Lam, W Tempel, MF Amaya, C Xu, L Dombrovski, W Qiu, ...PloS one 6 (6), e18919, 2011201
186
2011
Histone Arg modifications and p53 regulate the expression of OKL38, a mediator of apoptosis
H Yao, P Li, BJ Venters, S Zheng, PR Thompson, BF Pugh, Y WangJournal of Biological Chemistry 283 (29), 20060-20068, 2008200
178
2008
The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation
L Wu, BM Zee, Y Wang, BA Garcia, Y DouMolecular cell 43 (1), 132-144, 2011201
161
2011
Anticancer peptidylarginine deiminase (PAD) inhibitors regulate the autophagy flux and the mammalian target of rapamycin complex 1 activity
Y Wang, P Li, S Wang, J Hu, XA Chen, J Wu, M Fisher, K Oshaben, ...Journal of Biological Chemistry 287 (31), 25941-25953, 2012201
155
2012
Coordination of PAD4 and HDAC2 in the regulation of p53-target gene expression
P Li, D Wang, H Yao, P Doret, G Hao, Q Shen, H Qiu, X Zhang, Y Wang, ...Oncogene 29 (21), 3153-3162, 2010201
147
2010

Referred From: https://scholar.google.com/citations?user=YuWyvkMAAAAJ&hl=en

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Citations 15781
h-index 44
i10-index 48
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