Author

Thomas Lufkin

Bayard and Virginia Clarkson Endowed Chair in Biology, Department of Biology, Clarkson University - Cited by 13,938 - Regenerative Medicine - Embryonic Stem Cells - Skeletal Development - Genomics - Transgenic - Embryology

Biography

Thomas Lufkin working as Professor of Biology at Clarkson University, Newyork, USA. His research is in the novel area of Developmental Genomics and Regenerative Medicine with a focus on the molecular mechanisms controlling vertebral column development and an emphasis on early embryogenesis and embryonic stem cell commitment to specific differentiation pathways. We are working on understanding the gene regulatory networks (GRNs) that govern normal embryonic development of the vertebral column and intervertebral disc (IVD).
Title
Cited by
Year
Uniform, optimal signal processing of mapped deep-sequencing data
V Kumar, M Muratani, NA Rayan, P Kraus, T Lufkin, HH Ng, S PrabhakarNature biotechnology 31 (7), 615-622, 2013201
170
2013
In vivo epigenomic profiling of germ cells reveals germ cell molecular signatures
JH Ng, V Kumar, M Muratani, P Kraus, JC Yeo, LP Yaw, K Xue, T Lufkin, ...Developmental cell 24 (3), 324-333, 2013201
139
2013
Klf2 is an essential factor that sustains ground state pluripotency
JC Yeo, J Jiang, ZY Tan, GR Yim, JH Ng, J Göke, P Kraus, H Liang, ...Cell stem cell 14 (6), 864-872, 2014201
130
2014
Bridging the gap: understanding embryonic intervertebral disc development
V Sivakamasundari, T LufkinCell & developmental biology 1 (2), 2012201
63
2012
Isolation and 3D expansion of multipotent Sox9+ mouse lung progenitors
M Nichane, A Javed, V Sivakamasundari, M Ganesan, LT Ang, P Kraus, ...Nature methods 14 (12), 1205-1212, 2017201
60
2017
A developmental transcriptomic analysis of Pax1 and Pax9 in embryonic intervertebral disc development
V Sivakamasundari, P Kraus, W Sun, X Hu, SL Lim, S Prabhakar, T LufkinBiology open 6 (2), 187-199, 2017201
57
2017
51
2013
Making sense of Dlx1 antisense RNA
P Kraus, V Sivakamasundari, SL Lim, X Xing, L Lipovich, T LufkinDevelopmental biology 376 (2), 224-235, 2013201
47
2013
Comprehensive benchmarking reveals H2BK20 acetylation as a distinctive signature of cell-state-specific enhancers and promoters
V Kumar, NA Rayan, M Muratani, S Lim, B Elanggovan, L Xin, T Lu, ...Genome research 26 (5), 612-623, 2016201
29
2016
Potential biomarkers of the mature intervertebral disc identified at the single cell level
K Li, D Kapper, B Youngs, V Kocsis, S Mondal, P Kraus, T LufkinJournal of Anatomy 234 (1), 16-32, 2019201
29
2019
Implications for a stem cell regenerative medicine based approach to human intervertebral disk degeneration
P Kraus, T LufkinFrontiers in Cell and Developmental Biology 5, 17, 2017201
29
2017
Ontogenic identification and analysis of mesenchymal stromal cell populations during mouse limb and long bone development
G Nusspaumer, S Jaiswal, A Barbero, R Reinhardt, DI Ronen, A Haumer, ...Stem cell reports 9 (4), 1124-1138, 2017201
28
2017
Tetratricopeptide repeat domain 9A negatively regulates estrogen receptor alpha activity
S Shrestha, Y Sun, T Lufkin, P Kraus, Y Or, YA Garcia, N Guy, P Ramos, ...International journal of biological sciences 11 (4), 434, 2015201
22
2015
Pleiotropic functions for transcription factor zscan10
P Kraus, S V, HB Yu, X Xing, SL Lim, T Adler, JAA Pimentel, L Becker, ...PLoS One 9 (8), e104568, 2014201
21
2014
Mouse strain specific gene expression differences for illumina microarray expression profiling in embryos
P Kraus, X Xing, SL Lim, ME Fun, V Sivakamasundari, SP Yap, H Lee, ...BMC research notes 5 (1), 1-17, 2012201
19
2012
Tetratricopeptide repeat domain 9A modulates anxiety-like behavior in female mice
LW Lim, S Shrestha, YZ Or, SZK Tan, HH Chung, Y Sun, CL Lim, ...Scientific reports 6 (1), 37568, 2016201
17
2016
An integrative developmental genomics and systems biology approach to identify an in vivo Sox trio-mediated gene regulatory network in murine embryos
WJ Lee, S Chatterjee, SP Yap, SL Lim, X Xing, P Kraus, W Sun, X Hu, ...BioMed Research International 2017, 2017201
16
2017