Author

Satish Kumar Nandakumar

Albert Einstein College of Medicine - Cited by 1,248 - Hematopoiesis - GWAS - Leukemia

Biography

Dr. Nandakumar received his PhD in biomedical sciences from the University of Tennessee Health Science Center in 2014. He received training in hematopoiesis and the development of gene delivery methods into hematopoietic stem cells using lentiviral vectors. During his graduate research he studied the role of transcription factor GATA2 in mouse hematopoietic stem cells, as well as myeloid leukemia. Dr. Nandakumar is currently a postdoctoral researcher at Boston Children’s Hospital in affiliation with Harvard Medical School. He uses human genetic studies, called genome wide association studies (GWAS), to identify genes and gene variants affecting production of human blood cells
Title
Cited by
Year
Inherited causes of clonal haematopoiesis in 97,691 whole genomes
AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, EL Bao, SM Zekavat, ...Nature 586 (7831), 763-768, 2020202
328
2020
Systematic functional dissection of common genetic variation affecting red blood cell traits
JC Ulirsch, SK Nandakumar, L Wang, FC Giani, X Zhang, P Rogov, ...Cell 165 (6), 1530-1545, 2016201
294
2016
Advances in understanding erythropoiesis: evolving perspectives
SK Nandakumar, JC Ulirsch, VG SankaranBritish journal of haematology 173 (2), 206-218, 2016201
155
2016
Transcriptional states and chromatin accessibility underlying human erythropoiesis
LS Ludwig, CA Lareau, EL Bao, SK Nandakumar, C Muus, JC Ulirsch, ...Cell reports 27 (11), 3228-3240. e7, 2019201
122
2019
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
EL Bao, SK Nandakumar, X Liao, AG Bick, J Karjalainen, M Tabaka, ...Nature 586 (7831), 769-775, 2020202
89
2020
Low-level GATA2 overexpression promotes myeloid progenitor self-renewal and blocks lymphoid differentiation in mice
SK Nandakumar, K Johnson, SL Throm, TI Pestina, G Neale, DA PersonsExperimental hematology 43 (7), 565-577. e10, 2015201
53
2015
Nfix is a novel regulator of murine hematopoietic stem and progenitor cell survival
P Holmfeldt, J Pardieck, AC Saulsberry, SK Nandakumar, D Finkelstein, ...Blood, The Journal of the American Society of Hematology 122 (17), 2987-2996, 2013201
42
2013
Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms
MH Guo, SK Nandakumar, JC Ulirsch, SM Zekavat, JD Buenrostro, ...Proceedings of the National Academy of Sciences 114 (3), E327-E336, 2017201
39
2017
Infantile myelofibrosis and myeloproliferation with CDC42 dysfunction
JM Verboon, D Mahmut, AR Kim, M Nakamura, NJ Abdulhay, ...Journal of clinical immunology 40, 554-566, 2020202
26
2020
Inherited causes of clonal hematopoiesis of indeterminate potential in TOPMed whole genomes
AG Bick, JS Weinstock, SK Nandakumar, CP Fulco, MJ Leventhal, EL Bao, ...BioRxiv, 782748, 2019201
21
2019
Common variants in signaling transcription-factor-binding sites drive phenotypic variability in red blood cell traits
A Choudhuri, E Trompouki, BJ Abraham, LM Colli, KH Kock, W Mallard, ...Nature genetics 52 (12), 1333-1345,
20
2020
A unified model of human hemoglobin switching through single-cell genome editing
Y Shen, JM Verboon, Y Zhang, N Liu, YJ Kim, S Marglous, ...Nature communications 12 (1), 4991, 2021202
18
2021
Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis
SK Nandakumar, SK McFarland, LM Mateyka, CA Lareau, JC Ulirsch, ...Elife 8, e44080, 2019201
15
2019
In the blood: connecting variant to function in human hematopoiesis
SK Nandakumar, X Liao, VG SankaranTrends in Genetics 36 (8), 563-576, 2020202
11
2020
A genetic disorder reveals a hematopoietic stem cell regulatory network co-opted in leukemia
RA Voit, L Tao, F Yu, LD Cato, B Cohen, TJ Fleming, M Antoszewski, ...Nature Immunology 24 (1), 6-83, 2023202
9
2023
Shared and distinct genetic etiologies for different types of clonal hematopoiesis
DW Brown, LD Cato, Y Zhao, SK Nandakumar, EL Bao, EJ Gardner, ...BioRxiv, 2022.03. 14.483644, 2022202
5
2022
Genetic predisposition to myeloproliferative neoplasms implicates hematopoietic stem cell biology
EL Bao, SK Nandakumar, X Liao, A Bick, J Karjalainen, M Tabaka, OI Gan, ...bioRxiv, 790626, 20920
1
2019