Author

Rohan Samarakoon

Associate Professor, Albany Medical College - Cited by 2,556 - TGF-beta - renal fibrosis - vascular disease - cell signaling

Biography

Dr. Rohan Samarakoon is currently working as a Assistant Professor in the Department of Regenerative and Cancer Cell Biology, Albany Medical College , USA. His research interests includes Gene expression, tissue fibrosis, Cell signaling and migration. He is serving as an editorial member and reviewer of several international reputed journals. Dr. Rohan Samarakoon is the member of many international affiliations. He has successfully completed his Administrative responsibilities. He has authored of many research articles/books related to Gene expression, tissue fibrosis, Cell signaling and migration.
Title
Cited by
Year
TGF-β signaling in tissue fibrosis: redox controls, target genes and therapeutic opportunities
R Samarakoon, JM Overstreet, PJ HigginsCellular signalling 25 (1), 264-268, 2013201
368
2013
PAI-1: an integrator of cell signaling and migration
RP Czekay, CE Wilkins-Port, SP Higgins, J Freytag, JM Overstreet, ...International journal of cell biology 2011, 2011201
206
2011
TGF-β1→ SMAD/p53/USF2→ PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis
R Samarakoon, JM Overstreet, SP Higgins, PJ HigginsCell and tissue research 347, 117-128, 2012201
164
2012
Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species
R Samarakoon, AD Dobberfuhl, C Cooley, JM Overstreet, S Patel, ...Cellular signalling 25 (11), 2198-2209, 2013201
163
2013
TGF-β1/p53 signaling in renal fibrogenesis
SP Higgins, Y Tang, CE Higgins, B Mian, W Zhang, RP Czekay, ...Cellular signalling 43, 1-10, 2018201
113
2018
Redox control of p53 in the transcriptional regulation of TGF-β1 target genes through SMAD cooperativity
JM Overstreet, R Samarakoon, KK Meldrum, PJ HigginsCellular signalling 26 (7), 1427-1436, 2014201
92
2014
Redox-induced Src kinase and caveolin-1 signaling in TGF-β1-initiated SMAD2/3 activation and PAI-1 expression
R Samarakoon, SS Chitnis, SP Higgins, CE Higgins, JC Krepinsky, ...PloS one 6 (7), e22896, 2011201
76
2011
Deregulation of Hippo–TAZ pathway during renal injury confers a fibrotic maladaptive phenotype
S Anorga, JM Overstreet, LL Falke, J Tang, RG Goldschmeding, ...The FASEB Journal 32 (5), 2644, 2018201
69
2018
Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3‐and p53‐dependent fibrotic responses
R Samarakoon, S Helo, AD Dobberfuhl, NS Khakoo, L Falke, ...The Journal of pathology 236 (4), 421-432, 2015201
67
2015
Deregulation of negative controls on TGF-β1 signaling in tumor progression
J Tang, CC Gifford, R Samarakoon, PJ HigginsCancers 10 (6), 159, 2018201
62
2018
PAI-1 mediates the TGF-β1+ EGF-induced “scatter” response in transformed human keratinocytes
J Freytag, CE Wilkins-Port, CE Higgins, SP Higgins, R Samarakoon, ...Journal of Investigative Dermatology 130 (9), 2179-2190, 2010201
56
2010
Linking cell structure to gene regulation: signaling events and expression controls on the model genes PAI-1 and CTGF
R Samarakoon, M Goppelt-Struebe, PJ HigginsCellular signalling 22 (10), 1413-1419, 2010201
56
2010
Differential requirement for MEK/ERK and SMAD signaling in PAI-1 and CTGF expression in response to microtubule disruption
R Samarakoon, CE Higgins, SP Higgins, PJ HigginsCellular signalling 21 (6), 986-995, 2009200
56
2009
Rac-GTPase promotes fibrotic TGF-β1 signaling and chronic kidney disease via EGFR, p53, and Hippo/YAP/TAZ pathways
S Patel, J Tang, JM Overstreet, S Anorga, F Lian, A Arnouk, ...The FASEB Journal 33 (9), 9797, 2019201
45
2019
The TGF-β1/p53/PAI-1 signaling axis in vascular senescence: Role of caveolin-1
R Samarakoon, SP Higgins, CE Higgins, PJ HigginsBiomolecules 9 (8), 341, 2019201
40
2019
Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses
JM Overstreet, R Samarakoon, D Cardona-Grau, R Goldschmeding, ...The FASEB Journal 29 (4), 1258, 2015201
37
2015
Negative regulators of TGF-β1 signaling in renal fibrosis; pathological mechanisms and novel therapeutic opportunities
CC Gifford, J Tang, A Costello, NS Khakoo, TQ Nguyen, ...Clinical science 135 (2), 275-303, 2021202
33
2021
Cancer-associated fibroblasts: mechanisms of tumor progression and novel therapeutic targets
RP Czekay, DJ Cheon, R Samarakoon, SM Kutz, PJ HigginsCancers 14 (5), 1231, 2022202
30
2022
Loss of expression of protein phosphatase magnesium-dependent 1A during kidney injury promotes fibrotic maladaptive repair
R Samarakoon, A Rehfuss, NS Khakoo, LL Falke, AD Dobberfuhl, S Helo, ...The FASEB Journal 30 (10), 3308, 2016201
25
2016
TGF-β1–p53 cooperativity regulates a profibrotic genomic program in the kidney: Molecular mechanisms and clinical implications
CE Higgins, J Tang, BM Mian, SP Higgins, CC Gifford, DJ Conti, ...The FASEB Journal 33 (10), 10596, 202
19
2019

Referred From: https://scholar.google.com/citations?user=jPt1jxEAAAAJ&hl=en

Cited by
Citations 2556
h-index 27
i10-index 34
Recommended Journals
Open Access Journals