Author

Liang Ge

Tsinghua University - Cited by 15,195 - autophagy - vesicular transport - secretion

Biography

Liang Ge pursued his PhD in the lab of Dr Bao-Liang Song at the Institutes of Biochemistry and Cell Biology, Chinese Academy of Sciences, where he studied the molecular mechanisms of cholesterol absorption. In 2011 he moved to California for a postdoc and later a research specialist position with Randy Schekman at the University of California, Berkeley. There, he discovered key roles for LC3 lipidation and the ER–Golgi intermediate compartment in autophagosome biogenesis. Liang established his group in the School of Life Sciences at Tsinghua University at the end of 2017.
Title
Cited by
Year
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...autophagy 17 (1), 1-382, 202112432202
12432
2021
The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis
L Ge, D Melville, M Zhang, R Schekmanelife 2, e00947, 2013201
422
2013
The cholesterol absorption inhibitor ezetimibe acts by blocking the sterol-induced internalization of NPC1L1
L Ge, J Wang, W Qi, HH Miao, J Cao, YX Qu, BL Li, BL SongCell metabolism 7 (6), 508-519, 2008200
387
2008
Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion
M Zhang, SJ Kenny, L Ge, K Xu, R Schekmanelife 4, e11205, 2015201
312
2015
Phosphatidylinositol 3-kinase and COPII generate LC3 lipidation vesicles from the ER-Golgi intermediate compartment
L Ge, M Zhang, R Schekmanelife 3, e04135, 2014201
172
2014
The noncanonical role of ULK/ATG1 in ER-to-Golgi trafficking is essential for cellular homeostasis
JH Joo, B Wang, E Frankel, L Ge, L Xu, R Iyengar, XJ Li-Harms, C Wright, ...Molecular cell 62 (4), 491-506, 2061201
161
2016
Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake
L Ge, W Qi, LJ Wang, HH Miao, YX Qu, BL Li, BL SongProceedings of the National Academy of Sciences 108 (2), 551-556, 2011201
156
2011
Remodeling of ER‐exit sites initiates a membrane supply pathway for autophagosome biogenesis
L Ge, M Zhang, SJ Kenny, D Liu, M Maeda, K Saito, A Mathur, K Xu, ...EMBO reports 18 (9), 1586-1603, 2017201
144
2017
A translocation pathway for vesicle-mediated unconventional protein secretion
M Zhang, L Liu, X Lin, Y Wang, Y Li, Q Guo, S Li, Y Sun, X Tao, D Zhang, ...Cell 181 (3), 637-652. e15, 2020202
115
2020
The N-terminal domain of NPC1L1 protein binds cholesterol and plays essential roles in cholesterol uptake
JH Zhang, L Ge, W Qi, L Zhang, HH Miao, BL Li, M Yang, BL SongJournal of Biological Chemistry 286 (28), 25088-25097, 2011201
106
2011
Avoidance of autophagy mediated by PlcA or ActA is required for Listeria monocytogenes growth in macrophages
G Mitchell, L Ge, Q Huang, C Chen, S Kianian, MF Roberts, R Schekman, ...Infection and immunity 83 (5), 2175-2184, 2015201
95
2015
Ufd1 is a cofactor of gp78 and plays a key role in cholesterol metabolism by regulating the stability of HMG-CoA reductase
J Cao, J Wang, W Qi, HH Miao, J Wang, L Ge, RA DeBose-Boyd, JJ Tang, ...Cell metabolism 6 (2), 115-128, 2007200
95
2007
Molecular characterization of the NPC1L1 variants identified from cholesterol low absorbers
LJ Wang, J Wang, N Li, L Ge, BL Li, BL SongJournal of Biological Chemistry 286 (9), 7397-7408, 2011201
79
2011
Membrane topology of human NPC1L1, a key protein in enterohepatic cholesterol absorption
J Wang, BB Chu, L Ge, BL Li, Y Yan, BL SongJournal of lipid research 50 (8), 1653-1662, 2009200
77
2009
Requirement of myosin Vb· Rab11a· Rab11-FIP2 complex in cholesterol-regulated translocation of NPC1L1 to the cell surface
BB Chu, L Ge, C Xie, Y Zhao, HH Miao, J Wang, BL Li, BL SongJournal of Biological Chemistry 284 (33), 22481-22490, 2009200
67
2009
The protein-vesicle network of autophagy
L Ge, S Baskaran, R Schekman, JH HurleyCurrent opinion in cell biology 29, 18-24, 2014201
66
2014
The ER-Golgi intermediate compartment feeds the phagophore membrane
L Ge, R SchekmanAutophagy 10 (1), 170-172, 2014201
58
2014
Regulation of LC3 lipidation by the autophagy-specific class III phosphatidylinositol-3 kinase complex
LW Brier, L Ge, G Stjepanovic, AM Thelen, JH Hurley, R SchekmanMolecular biology of the cell 30 (9), 1098-1107, 2019201
52
2019
CCT2 is an aggrephagy receptor for clearance of solid protein aggregates
X Ma, C Lu, Y Chen, S Li, N Ma, X Tao, Y Li, J Wang, M Zhou, YB Yan, ...Cell 185 (8), 1325-13. e22, 2022202
45
2022
Biogenesis of autophagosomal precursors for LC3 lipidation from the ER-Golgi intermediate compartment
L Ge, L Wilz, R SchekmanAutophagy 11 (12), 2372-2374, 2015201
39
2015

Referred From: https://scholar.google.com/citations?user=axVBS5oAAAAJ&hl=en

Cited by
Citations 15195
h-index 21
i10-index 23
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