Author

Heedoo Lee

Changwon National University - Cited by 2,042 - Immunophysiology - Respiratory disease - Lung injury and inflammation - Extracellular vesicles - Exosomes

Biography

Dr. Heedoo Lee is a professor in the Department of Biology and Chemistry at Changwon National University in Korea. His main research topic is the biological/physiological function of extracellular vesicles (EVs) and non-coding RNAs in pulmonary diseases, including acute lung injury and acute respiratory distress syndrome. In 2013, he obtained his PhD from Yonsei University, Korea with a support of BK21 PLUS (Brain Korea 21 Program for Leading Universities & Students), which was supported by the Korean government. During 2019 he had postdoctoral training at Washington University in St. Louis, Brigham, Women's Hospital and Boston University School of Medicine.
Title
Cited by
Year
Enrichment of selective miRNAs in exosomes and delivery of exosomal miRNAs in vitro and in vivo
D Zhang, H Lee, Z Zhu, JK Minhas, Y JinAmerican Journal of Physiology-Lung Cellular and Molecular Physiology 312 (1 …, 2017201
249
2017
Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs
H Lee, D Zhang, Z Zhu, CS Dela Cruz, Y JinScientific reports 6 (1), 35250, 2016201
149
2016
Exosome-mediated small RNA delivery: a novel therapeutic approach for inflammatory lung responses
D Zhang, H Lee, X Wang, A Rai, M Groot, Y JinMolecular Therapy 26 (9), 2119-2130, 2018201
136
2018
Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli
H Lee, C Li, Y Zhang, D Zhang, LE Otterbein, Y JinJournal of Experimental Medicine 216 (9), 2202-2220, 2019201
127
2019
A potential role of microvesicle-containing miR-223/142 in lung inflammation
D Zhang, H Lee, X Wang, M Groot, L Sharma, CSD Cruz, Y JinThorax 74 (9), 865-874, 2019201
109
2019
Macrophage-derived apoptotic bodies promote the proliferation of the recipient cells via shuttling microRNA-221/222
Z Zhu, D Zhang, H Lee, AA Menon, J Wu, K Hu, Y JinJournal of Leucocyte Biology 101 (6), 1349-1359, 2017201
96
2017
Exosomes derived from human macrophages suppress endothelial cell migration by controlling integrin trafficking
HD Lee, YH Kim, DS KimEuropean journal of immunology 44 (4), 1156-1169, 2014201
88
2014
Extracellular vesicle: an emerging mediator of intercellular crosstalk in lung inflammation and injury
H Lee, E Abston, D Zhang, A Rai, Y JinFrontiers in Immunology 9, 924, 2018201
82
2018
Lung epithelial cell–derived microvesicles regulate macrophage migration via MicroRNA-17/221–induced integrin β1 recycling
H Lee, D Zhang, J Wu, LE Otterbein, Y JinThe Journal of Immunology 199 (4), 1453-1464, 2017201
81
2017
Identification of miRNA-rich vesicles in bronchoalveolar lavage fluid: Insights into the function and heterogeneity of extracellular vesicles
H Lee, M Groot, M Pinilla-Vera, LE Fredenburgh, Y JinJournal of Controlled Release 294, 43-52, 2019201
76
2019
Functional evidence of pulmonary extracellular vesicles in infectious and noninfectious lung inflammation
H Lee, D Zhang, DL Laskin, Y JinThe Journal of Immunology 201 (5), 1500-1509, 2018201
76
2018
Long noncoding RNA FOXD3-AS1 regulates oxidative stress-induced apoptosis via sponging microRNA-150
D Zhang, H Lee, JA Haspel, Y JinThe FASEB Journal 31 (10), 4472, 2017201
63
2017
Exosome release of ADAM15 and the functional implications of human macrophage‐derived ADAM15 exosomes
HD Lee, BH Koo, YH Kim, OH Jeon, DS KimThe FASEB Journal 26 (7), 3084-3095, 2012201
56
2012
miR-185 mediates lung epithelial cell death after oxidative stress
D Zhang, H Lee, Y Cao, CS Dela Cruz, Y JinAmerican Journal of Physiology-Lung Cellular and Molecular Physiology 310 (7 …, 2016201
51
2016
Mesencephalic Astrocyte–Derived Neurotrophic Factor as a Urine Biomarker for Endoplasmic Reticulum Stress–Related Kidney Diseases
Y Kim, H Lee, SR Manson, M Lindahl, B Evans, JH Miner, F Urano, ...Journal of the American Society of Nephrology: JASN 27 (10), 2974, 2016201
51
2016
Emerging role of extracellular vesicles in the respiratory system
J Holtzman, H LeeExperimental & Molecular Medicine 52 (6), 887-895, 2020202
31
2020
Integrin αvβ3-mediated transcriptional regulation of TIMP-1 in a human ovarian cancer cell line
DS Kim, OH Jeon, HD Lee, KH Yoo, DS KimBiochemical and biophysical research communications 377 (2), 479-483, 2008200
28
2008
Tubular overexpression of angiopoietin-1 attenuates renal fibrosis
S Singh, SR Manson, H Lee, Y Kim, T Liu, Q Guo, JJ Geminiani, PF Austin, ...PloS one 11 (7), e0158908, 2016201
27
2016