Author

Aimin Liu

The Pennsylvania State University - Cited by 5,223 - Biology

Biography

Dr. Aimin Liu is an associate professor at the Pennsylvania State University, USA. He obtained his PhD from New York University Medical Center, studying the roles of fibroblast growth factors in midbrain and cerebellum development. He then received postdoctoral training under the supervision of Drs. Lee Niswander and Kathryn Anderson at the Sloan-Kettering Institute and made the discovery that the primary cilium regulates Gli transcription factor activation and proteolytic processing in the mouse. The research in his lab is now focused on the molecular mechanisms of cilia biogenesis and the regulation of the Hedgehog signal transduction in mammals.
Title
Cited by
Year
Hedgehog signalling in the mouse requires intraflagellar transport proteins
D Huangfu, A Liu, AS Rakeman, NS Murcia, L Niswander, KV AndersonNature 426 (6962), 83-87, 2003200
1508
2003
Mouse intraflagellar transport proteins regulate both the activator and repressor functions of Gli transcription factors
A Liu, B Wang, LA NiswanderOxford University Press for The Company of Biologists Limited 132 (13), 3103 …, 2005200
607
2005
Bone morphogenetic protein signalling and vertebrate nervous system development
A Liu, LA NiswanderNature Reviews Neuroscience 6 (12), 945-954, 2005200
429
2005
Otx2, Gbx2 and Fgf8 interact to position and maintain a mid–hindbrain organizer
AL Joyner, A Liu, S MilletCurrent opinion in cell biology 12 (6), 736-741, 2000200
334
2000
Early anterior/posterior patterning of the midbrain and cerebellum
A Liu, AL JoynerAnnual review of neuroscience 24 (1), 869-896, 2001200
270
2001
EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region
A Liu, AL JoynerDevelopment 128 (2), 181-191, 2001200
193
2001
Suppressor of Fused inhibits mammalian Hedgehog signaling in the absence of cilia
J Jia, Å Kolterud, H Zeng, A Hoover, S Teglund, R Toftgård, A LiuDevelopmental biology 330 (2), 452-460, 2009200
158
2009
Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion
C Pyrgaki, A Liu, L NiswanderDevelopmental biology 353 (1), 38-49, 2011201
152
2011
C2cd3 is critical for centriolar distal appendage assembly and ciliary vesicle docking in mammals
X Ye, H Zeng, G Ning, JF Reiter, A LiuProceedings of the National Academy of Sciences 111 (6), 2164-2169, 2014201
140
2014
Modeling microcephaly with cerebral organoids reveals a WDR62–CEP170–KIF2A pathway promoting cilium disassembly in neural progenitors
W Zhang, SL Yang, M Yang, S Herrlinger, Q Shao, JL Collar, E Fierro, ...Nature communications 10 (1), 2612, 2019201
128
2019
FGF17b and FGF18 have different midbrain regulatory properties from FGF8b or activated FGF receptors
A Liu, JYH Li, C Bromleigh, Z Lao, LA Niswander, AL JoynerOxford University Press for The Company of Biologists Limited 130 (25), 6175 …, 2003200
122
2003
PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals
H Zeng, AN Hoover, A LiuDevelopmental biology 339 (2), 418-428, 2010201
114
2010
C2cd3 is required for cilia formation and Hedgehog signaling in mouse
AN Hoover, A Wynkoop, H Zeng, J Jia, LA Niswander, A LiuOxford University Press for The Company of Biologists Limited 135 (24), 4049 …, 2008200
101
2008
Planar cell polarity effector gene Fuzzy regulates cilia formation and Hedgehog signal transduction in mouse
W Heydeck, H Zeng, A LiuDevelopmental Dynamics 238 (12), 3035-3042, 2009200
93
2009
Coordinated translocation of mammalian Gli proteins and suppressor of fused to the primary cilium
H Zeng, J Jia, A LiuPloS one 5 (12), e15900, 2010201
93
2010
Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling
H Cai, A LiuProceedings of the National Academy of Sciences 113 (51), 14751-14756, 2016201
55
2016
Centrosomal protein DZIP1 regulates Hedgehog signaling by promoting cytoplasmic retention of transcription factor GLI3 and affecting ciliogenesis
C Wang, WC Low, A Liu, B WangJournal of Biological Chemistry 288 (41), 29518-29529, 2013201
44
2013
Dual function of suppressor of fused in Hh pathway activation and mouse spinal cord patterning
J Liu, W Heydeck, H Zeng, A LiuDevelopmental biology 362 (2), 141-153, 2012201
37
2012
Hedgehog-activated Fat4 and PCP pathways mediate mesenchymal cell clustering and villus formation in gut development
A Rao-Bhatia, M Zhu, WC Yin, S Coquenlorge, X Zhang, J Woo, Y Sun, ...Developmental cell 52 (5), 647-658. e6, 2020202
34
2020
PCP effector proteins inturned and fuzzy play nonredundant roles in the patterning but not convergent extension of mammalian neural tube
W Heydeck, A LiuDevelopmental Dynamics 240 (8), 1938-1948, 2011201
31
2011

Referred From: https://scholar.google.com/citations?user=watux_oAAAAJ&hl=en

Cited by
Citations 5223
h-index 24
i10-index 32
Recommended Journals
Open Access Journals