Author

Robert J Levy

The Children's Hospital of Philadelphia - Cited by 19,840 - heart valves - biomaterials - calcification - local delivery - gene therapy

Biography

Robert J. Levy, MD, is a board-certified attending cardiologist in the Cardiac Center and the William J. Rashkind Endowed Chair in Pediatric Cardiology at Children's Hospital of Philadelphia.   Areas of Expertise: Cardiac arrhythmias and post-angioplasty surgery, Research concerning site-specific therapy for cardiovascular disease focusing on valve replacement surgery
Title
Cited by
Year
High field gradient targeting of magnetic nanoparticle-loaded endothelial cells to the surfaces of steel stents
B Polyak, I Fishbein, M Chorny, I Alferiev, D Williams, B Yellen, ...Proceedings of the National Academy of Sciences 105 (2), 698-703, 2008200
303
2008
Targeting stents with local delivery of paclitaxel-loaded magnetic nanoparticles using uniform fields
M Chorny, I Fishbein, BB Yellen, IS Alferiev, M Bakay, S Ganta, R Adamo, ...Proceedings of the National Academy of Sciences 107 (18), 8346-8351, 2010201
229
2010
Transforming growth factor-β1 mechanisms in aortic valve calcification: increased alkaline phosphatase and related events
JN Clark-Greuel, JM Connolly, E Sorichillo, NR Narula, HS Rapoport, ...The Annals of thoracic surgery 83 (3), 946-953, 2007200
190
2007
Micropatterning of three-dimensional electrospun polyurethane vascular grafts
P Uttayarat, A Perets, M Li, P Pimton, SJ Stachelek, I Alferiev, ...Acta biomaterialia 6 (11), 4229-4237, 2010201
168
2010
In-vivo dynamic deformation of the mitral valve anterior leaflet
MS Sacks, Y Enomoto, JR Graybill, WD Merryman, A Zeeshan, ...The Annals of thoracic surgery 82 (4), 1369-1377, 2006200
155
2006
Magnetically driven plasmid DNA delivery with biodegradable polymeric nanoparticles
M Chorny, B Polyak, IS Alferiev, K Walsh, G Friedman, RJ LevyThe FASEB Journal 21 (10), 2510, 2007200
129
2007
Endothelial delivery of antioxidant enzymes loaded into non-polymeric magnetic nanoparticles
M Chorny, E Hood, RJ Levy, VR MuzykantovJournal of Controlled Release 146 (1), 144-151, 2010201
128
2010
Bisphosphonate-mediated gene vector delivery from the metal surfaces of stents
I Fishbein, IS Alferiev, O Nyanguile, R Gaster, JM Vohs, GS Wong, ...Proceedings of the National Academy of Sciences 103 (1), 159-164, 2006200
109
2006
Local delivery of gene vectors from bare-metal stents by use of a biodegradable synthetic complex inhibits in-stent restenosis in rat carotid arteries
I Fishbein, I Alferiev, M Bakay, SJ Stachelek, P Sobolewski, M Lai, H Choi, ...Circulation 117 (16), 2096-2103, 2008200
92
2008
Endothelial targeting of nanocarriers loaded with antioxidant enzymes for protection against vascular oxidative stress and inflammation
ED Hood, M Chorny, CF Greineder, IS Alferiev, RJ Levy, VR MuzykantovBiomaterials 35 (11), 3708-3715, 2014201
92
2014
The effect of CD47 modified polymer surfaces on inflammatory cell attachment and activation
SJ Stachelek, MJ Finley, IS Alferiev, F Wang, RK Tsai, EC Eckells, ...Biomaterials 32 (19), 4317-4326, 2011201
81
2011
Compositions and methods for coating medical devices
S Goldstein, R Levy, V Labhasetwar, J BonadioUS Patent App. 11/068,735, 2006200
69
2006
Mechanisms of the in vivo inhibition of calcification of bioprosthetic porcine aortic valve cusps and aortic wall with triglycidylamine/mercapto bisphosphonate
HS Rapoport, JM Connolly, J Fulmer, N Dai, BH Murti, RC Gorman, ...Biomaterials 28 (4), 690-699, 2007200
68
2007
Diminished adhesion and activation of platelets and neutrophils with CD47 functionalized blood contacting surfaces
MJ Finley, L Rauova, IS Alferiev, JW Weisel, RJ Levy, SJ StachelekBiomaterials 33 (24), 5803-5811, 2012201
61
2012
Fenfluramine disrupts the mitral valve interstitial cell response to serotonin
JM Connolly, MA Bakay, JT Fulmer, RC Gorman, JH Gorman III, ...The American journal of pathology 175 (3), 988-997, 2009200
54
2009
Aortic valve cyclic stretch causes increased remodeling activity and enhanced serotonin receptor responsiveness
K Balachandran, MA Bakay, JM Connolly, X Zhang, AP Yoganathan, ...The Annals of thoracic surgery 92 (1), 147-1, 2011201
53
2011
Serotonin transporter mechanisms and cardiac disease
RJ LevyCirculation 113 (1), 2-4, 2006200
53
2006
Magnetically-driven biodegradable gene delivery nanoparticles formulated with surface-attached polycationic complex
M Chorny, B Polyak, I Fishbein, I Alferiev, RJ LevyUS Patent 7,846,201, 2010201
49
2010
Site-specific gene therapy for cardiovascular disease
I Fishbein, M Chorny, RJ LevyCurrent opinion in drug discovery & development 13 (2), 203, 2010201
46
2010
Magnetically responsive biodegradable nanoparticles enhance adenoviral gene transfer in cultured smooth muscle and endothelial cells
M Chorny, I Fishbein, I Alferiev, RJ LevyMolecular Pharmaceutics 6 (5), 1380-1387, 2009200
41
2009