Author

Nancy Lan Guo

West Virginia University - Cited by 3,736 - bioinformatics - cancer biomarkers - nanotoxicity

Biography

Dr. Guo got her Ph.D. in Computer and Information Science in 2004 and B.S. in Biochemistry and Molecular Biology in 1997. She is Program Assistant Director of West Virginia Clinical & Translational Science Institute for Biomedical Informatics.  She had 21 peer-reviewed publications in the past three years.  Her work in lung cancer gene signatures was nominated for 2007 CDC Excellence in Science Awards. Her work in breast cancer gene signatures was selected to feature the cover of Clinical Cancer Research [April, 2007] which received national news coverage from Newswise, Medical News Today, NewsRx, etc.
Title
Cited by
Year
Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells
Y Jing, LZ Liu, Y Jiang, Y Zhu, NL Guo, J Barnett, Y Rojanasakul, F Agani, ...Toxicological sciences 125 (1), 10-19, 2012201
206
2012
Cell permeability, migration, and reactive oxygen species induced by multiwalled carbon nanotubes in human microvascular endothelial cells
M Pacurari, Y Qian, W Fu, D Schwegler-Berry, M Ding, V Castranova, ...Journal of Toxicology and Environmental Health, Part A 75 (2), 112-128, 2012201
127
2012
The microRNA-200 family targets multiple non-small cell lung cancer prognostic markers in H1299 cells and BEAS-2B cells
M Pacurari, JB Addison, N Bondalapati, YW Wan, D Luo, Y Qian, ...International journal of oncology 43 (2), 548-560, 2013201
107
2013
Multiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosis
NL Guo, YW Wan, J Denvir, DW Porter, M Pacurari, MG Wolfarth, ...Journal of Toxicology and Environmental Health, Part A 75 (18), 1129-1153, 2012201
83
2012
Multi-walled carbon nanotubes induce human microvascular endothelial cellular effects in an alveolar-capillary co-culture with small airway epithelial cells
BN Snyder-Talkington, D Schwegler-Berry, V Castranova, Y Qian, NL GuoParticle and fibre toxicology 10 (1), 1-14, 2013201
81
2013
New perspectives for in vitro risk assessment of multiwalled carbon nanotubes: application of coculture and bioinformatics
BN Snyder-Talkington, Y Qian, V Castranova, NL GuoJournal of Toxicology and Environmental Health, Part B 15 (7), 468-492, 2012201
64
2012
System-based identification of toxicity pathways associated with multi-walled carbon nanotube-induced pathological responses
BN Snyder-Talkington, J Dymacek, DW Porter, MG Wolfarth, RR Mercer, ...Toxicology and applied pharmacology 272 (2), 476-489, 2013201
58
2013
Multi-walled carbon nanotube-induced gene expression in vitro: Concordance with in vivo studies
BN Snyder-Talkington, C Dong, X Zhao, J Dymacek, DW Porter, ...Toxicology 328, 66-74, 2015201
49
2015
mRNA and miRNA regulatory networks reflective of multi-walled carbon nanotube-induced lung inflammatory and fibrotic pathologies in mice
J Dymacek, BN Snyder-Talkington, DW Porter, RR Mercer, MG Wolfarth, ...Toxicological Sciences 144 (1), 51-64, 2015201
46
2015
mRNAs and miRNAs in whole blood associated with lung hyperplasia, fibrosis, and bronchiolo‐alveolar adenoma and adenocarcinoma after multi‐walled carbon nanotube inhalation …
BN Snyder‐Talkington, C Dong, LM Sargent, DW Porter, LM Staska, ...Journal of Applied Toxicology 36 (1), 161-174, 2016201
45
2016
Pathway-based identification of a smoking associated 6-gene signature predictive of lung cancer risk and survival
NL Guo, YW WanArtificial intelligence in medicine 55 (2), 97-105, 2012201
38
2012
Systematic analysis of multiwalled carbon nanotube-induced cellular signaling and gene expression in human small airway epithelial cells
BN Snyder-Talkington, M Pacurari, C Dong, SS Leonard, ...toxicological sciences 1 (1), 79-89, 2013201
33
2013
Multiwalled carbon nanotube-induced pulmonary inflammatory and fibrotic responses and genomic changes following aspiration exposure in mice: A 1-year postexposure study
BN Snyder-Talkington, C Dong, DW Porter, B Ducatman, MG Wolfarth, ...Journal of Toxicology and Environmental Health, Part A 79 (8), 352-366, 2016201
32
2016
Network-based identification of biomarkers coexpressed with multiple pathways
NL Guo, YW WanCancer informatics 13, CIN. S14054, 2014201
26
2014
Integrated transcriptomics, metabolomics, and lipidomics profiling in rat lung, blood, and serum for assessment of laser printer-emitted nanoparticle inhalation exposure …
NL Guo, TY Poh, S Pirela, MT Farcas, SH Chotirmall, WK Tham, SS Adav, ...International journal of molecular sciences 20 (24), 6348, 2019201
21
2019
A predictive 7-gene assay and prognostic protein biomarkers for non-small cell lung cancer
NL Guo, A Dowlati, RA Raese, C Dong, G Chen, DG Beer, J Shaffer, ...EBioMedicine 32, 102-110, 202
18
2018
A smoking-associated 7-gene signature for lung cancer diagnosis and prognosis
YW Wan, RA Raese, JE Fortney, C Xiao, D Luo, J Cavendish, LF Gibson, ...International journal of oncology 41 (4), 1387-1396, 2012201
15
2012